PGR - Expediting Vaccine Development in a Public Health Emergency: Lessons Learned and Not Learned



Date & Location
Wednesday, September 16, 2026, 8:00 AM - Saturday, September 16, 2028, 11:59 PM

Target Audience
Specialties - Pediatric Allergy and Immunology, Pediatric Infectious Disease

Overview

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Department of Pediatrics Grand Rounds: Hilleman Lectureship

Headshot of Mark FeinbergMark Feinberg, M.D., Ph.D., is president and CEO of IAVI where he leads a global team working to advance the development of vaccines and other biomedical innovations to protect against infection with HIV, tuberculosis, emerging viruses and other public health threats that disproportionately impact people living in low-income countries.

Prior to joining IAVI in 2015, Mark served as chief public health and science officer with Merck Vaccines. In this role, he helped advance the development and global availability of vaccines against rotavirus, human papillomavirus, and other infectious diseases. He also led a range of research initiatives to address unmet health needs in low-income countries including the coordination of a private-public partnership to expedite the development of an efficacious Ebola Zaire vaccine. Following the 2014-2016 Ebola outbreak in West Africa, Mark also played a central role in the establishment of the Coalition for Epidemic Preparedness Innovations (CEPI) and was the inaugural Chair of the CEPI Scientific Advisory Board. Previously, Mark spent more than 20 years exploring HIV/AIDS pathogenesis, treatment, and prevention research and the biology of emerging diseases in both academia and government.

Mark holds an M.D. and a Ph.D. from Stanford University, and B.A. degree from the University of Pennsylvania. He pursued post-graduate medical training in internal medicine at the Brigham and Women’s Hospital and postdoctoral fellowship training in the laboratory of Dr. David Baltimore at the Whitehead Institute. He has previously served as a faculty member at the University of California, San Francisco and the Emory University School of Medicine, as a medical officer in the Office of AIDS Research at the National Institutes of Health (NIH) and as a fellow in the Advanced Leadership Initiative at Harvard University. Mark is a Fellow of the American College of Physicians, and a member of the Council on Foreign Relations and the Association of American Physicians.

Disclosure Statement

Mark Feinberg, M.D., Ph.D (Speaker), Claire Castellano, MD, MPH, Melodie Noel, MD, Julia Sabella, MD, May Shum, MD, Andrea Szabo, MD, Jordan Orange MD, PhD, Daniel West, MD (Course Directors), and Tina Mannices, MS (CME Planner) have no relevant financial relationship with an ineligible company to disclose.

Release Date: 9/16/2026

Expiration Date: 9/16/2028


Objectives

While completing this module, reflect on the following objectives and consider how you would apply them to your practice:


  1. Identify lessons from the successful development of the Ebola vaccine ERVEBO® that may inform future vaccine development for outbreak-prone diseases affecting low- and middle-income countries
  2. Gain insights into ongoing efforts to expedite the development of a vaccine against Bundibugyo virus to address the current outbreak in the Democratic Republic of the Congo
  3. Understand the biologic and programmatic considerations for the development of vaccines targeting outbreak associated pathogens (e.g. filoviruses)
  4. Discuss how global partnerships, clinical trial design, manufacturing readiness, and regulatory strategy can accelerate vaccine availability for populations at greatest risk
  5. Understand considerations related to developing public health innovations when there is no commercial incentive

Accreditation

In support of improving patient care, Children’s Hospital of Philadelphia is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Designation of Credit

Physicians: Children’s Hospital of Philadelphia designates this live activity for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


Credits
AMA PRA Category 1 Credits™ (1.00 hours), Non-Physician AMA PRA Category 1 Credits™ Attendance (includes PA, RT, RDMS) (1.00 hours)

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