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6th Annual CHOP Immune Dysregulation Symposium - Going Down the DIRT Path

  • Overview
  • Faculty
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Add to Calendar 6th Annual CHOP Immune Dysregulation Symposium - Going Down the DIRT Path 6/7/2024 7:30:00 AM 6/7/2024 5:00:00 PM America/New_York For More Details: https://chop.cloud-cme.com/course/courseoverview?EID=4027 Description: A symposium hosted by the CHOP Multidisciplinary Immune Dysregulation Team forclinicians, researchers, and those who care for patients with complex multiorgan immunedisease. We will explore the pathway approach from mechanism to treatment of immunedysregulation. The event will include cutting edge talks, a debate on therapeutic decisionmaking,provocative cases, and more. CHOP Hub for Clinical Collaboration false MM/DD/YYYY


Date & Location
Friday, June 7, 2024, 7:30 AM - 5:00 PM, CHOP Hub for Clinical Collaboration

Overview
A symposium hosted by the CHOP Multidisciplinary Immune Dysregulation Team for
clinicians, researchers, and those who care for patients with complex multiorgan immune
disease. We will explore the pathway approach from mechanism to treatment of immune
dysregulation. The event will include cutting edge talks, a debate on therapeutic decisionmaking,
provocative cases, and more.

Objectives
In this full-day hybrid seminar, attendees will gain an understanding of:

  1. How to utilize pathways as a foundation for clinical care
  2. Organ system involvement in immune dysregulation
  3. Treatment approaches for immune dysregulation conditions

Registration

REGISTRATION IS FREE

Attending the conference in person includes continental breakfast, refreshments, lunch, and course materials.

Attending the conference virtually includes livestream access to the conference and access to view online course materials.

HOTEL INFORMATION
A block of rooms has been reserved at reduced rates at The Study located just a few blocks from Children’s Hospital. The group overnight rate is $259 single and double occupancy plus a 16.25% room tax. Participants are required to make their own hotel reservations by calling The Study directly at 215-387-1400. Please mention the name of the conference when making your reservation. The special room rate will be available until May 6, 2024. After that date, reservations will be accepted on a space and rate availability basis.

 https://reservations.travelclick.com/99716?groupID=4072402



Mitigation of Relevant Financial Relationships


Children's Hospital of Philadelphia adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Member Information
Role in activity
Nature of Relationship(s) / Name of Ineligible Company(s)
Sara Alehashemi, MD, MPH
Faculty
Hamid Bassiri, MD, PhD
Assistant Professor
Children's Hospital of Philadelphia
Faculty
Edward Behrens, MD
MD
Chop
Faculty
Scott Canna, MD
MD
CHOP
Faculty
Hana Conlon, CRNP
CRNP
Children's Hospital of Philadelphia
Faculty
Melissa Hines, MD
St Jude Children's Research Hospital
Faculty
Hal M. Hoffman, MD
Rady Children’s Hospital
Faculty
Andrew Hughes, MD, PhD
Fellow
CHOP
Faculty
Lionel Ivashkiv, MD
Weill Cornell (New York City) Medicine
Faculty
Michele Lambert, MD
Children's Hospital of Philadelphia
Faculty
Honoraria-Novartis AG|Grant or research support-Novartis AG|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Dova, Octapharma, Rigel, Argenx, Principia|Honoraria-Dova, Octapharma, Rigel, Argenx, Shionogi, Principia|Grant or research support-Dova, Octapharma, Rigel, Argenx, Principia|Membership on Advisory Committees or Review Panels, Board Membership, etc.-PDSA, 22qSociety, CDLS Foundation
Susan McClory, MD, PhD
Children's Hospital of Philadelphia
Faculty
Nothing to disclose
Jonathan Miner, MD
University of Pennsylvania
Faculty
Brittney N Newby, MD, PhD
CHOP
Faculty
Whitney Petrosa, CRNP
CRNP
The Children's Hospital of Philadelphia
Faculty
Nothing to disclose
Neil Romberg, MD
MD
chop
Faculty
Sunny Shin, MD
University of Pennsylvania
Faculty
Kathleen Sullivan, MD PhD
Chop
Faculty
Consulting Fee-Immune Deficiency Foundation|Consulting Fee-Elsevier|Consulting Fee-Enzyvant
David Teachey, MD
MD
CHOP
Faculty
Adeline Vanderver, MD
CHOP
Faculty

Friday, June 7, 2024

Breakfast and Registration
8:00AM - 8:30AM
Empiric JAK Inhibition in Inflammation NOS
8:30AM - 8:50AM
Whitney Petrosa, CRNP
Translational Therapeutics in Aicardi Goutières Syndrome, a Heritable Interferonopathy
8:50AM - 9:25AM
Adeline Vanderver, MD
DNA Damage and Inflamm-aging in Retinal Vasculopathy with Cerebral Leukoencephalopathy
9:25AM - 10:00AM
Jonathan Miner, MD
KEYNOTE Lecture: The Invitation to the Inflammation Party: The Role of Type I Interferons in Hemophagocytic Lymphohistiocytosis (HLH)
10:00AM - 10:50AM
Melissa Hines, MD
Break
10:50AM - 11:15AM
If at First You Don’t Succeed Try, Try Again: MAS825 in Refractory sJIA
11:15AM - 11:30AM
Hana Conlon, CRNP
Differences in Mouse and Human Inflammasome Responses to Infection
11:30AM - 12:05PM
Sunny Shin, MD
Anakinra-Associated Amyloidosis
12:05PM - 12:25PM
Sara Alehashemi, MD, MPH
KEYNOTE Lecture: Old and New Approaches to Targeting NLRP3 Mediated Diseases
12:25PM - 1:15PM
Hal M. Hoffman, MD
Lunch
1:15PM - 2:20PM
Fellow Case: A Case of HLH Due to UNC13D Deficiency
2:20PM - 2:40PM
Andrew Hughes, MD, PhD
Fellow Case: Journey to Remission: Conquering Refractory sJIA with Emapalumab
2:40PM - 3:00PM
Brittney N Newby, MD, PhD
HLH Debate — Treatment by Protocol, by Pathway, by Presentation
3:00PM - 3:55PM
Edward Behrens, MD
Susan McClory, MD, PhD
Neil Romberg, MD
KEYNOTE Lecture: Interferon Regulation of Inflammatory Cytokine Responses
3:55PM - 4:50PM
Lionel Ivashkiv, MD
Closing Remarks
4:50PM - 5:00PM
Edward Behrens, MD

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