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The Beckwith-Wiedemann Spectrum Symposium: Bridging Research and Care

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Add to Calendar The Beckwith-Wiedemann Spectrum Symposium: Bridging Research and Care 7/18/2025 5:00:00 PM 7/20/2025 12:30:00 PM America/New_York For More Details: https://chop.cloud-cme.com/course/courseoverview?EID=11078 Description: Deciphering Beckwith-Wiedemann Spectrum will provide updates on the current diagnostic and clinical management information and the latest research findings on the condition. Conference attendees will be educated on the vast spectrum of presenting clinical features, current clinical management practices, and common medical procedures. Researchers from Children's Hospital of Philadelphia will be joined by... CHOP Hub for Clinical Collaboration false MM/DD/YYYY


Date & Location
Friday, July 18, 2025, 5:00 PM - Sunday, July 20, 2025, 12:30 PM, CHOP Hub for Clinical Collaboration, Philadelphia, PA

Overview

Deciphering Beckwith-Wiedemann Spectrum will provide updates on the current diagnostic and clinical management information and the latest research findings on the condition. Conference attendees will be educated on the vast spectrum of presenting clinical features, current clinical management practices, and common medical procedures. Researchers from Children's Hospital of Philadelphia will be joined by collaborators from around the world to present ongoing BWSp research topics as well. Understanding this information is crucial in providing optimal care to patients with BWSp. This conference is designed for clinicians, families with children who have BWSp, and adults with BWSp. The audience will be encouraged to further educate other clinicians and caregivers at their home institution.


Objectives
  1. Describe the (epi)genetics and clinical features of BWSp.
  2. More accurately diagnose patients with BWSp.
  3. Improve clinical care of individuals with BWSp.
  4. Provide educational materials with providers at their home institution.
  5. Share the latest updates on BWSp research.

Registration

In-Person Registration Fees

Physicians: $75
Other Healthcare Providers: $50
Family: $10/adult

Attending the conference in person includes continental breakfast, refreshments, lunch, and course materials.

Virtual Registration Fees

Healthcare Providers: $40
Family: $20/family

Attending the conference virtually includes livestream access to the conference and access to view online course materials.


Accreditation

In support of improving patient care, this activity has been planned and implemented by the Children’s Hospital of Philadelphia. The Children’s Hospital of Philadelphia is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.


Credits
AMA PRA Category 1 Credits™ (9.25 hours), ANCC NCPD Contact Hours (9.25 hours), Non-Physician AMA PRA Category 1 Credits™ Attendance (includes PA, RT, RDMS) (9.25 hours)



Mitigation of Relevant Financial Relationships


Children's Hospital of Philadelphia adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Member Information
Role in activity
Nature of Relationship(s) / Name of Ineligible Company(s)
Evan Hathaway, MS, LCGC
Genetic Counselor
CHOP
Co-Director, Faculty
Nothing to disclose
Jennifer Kalish, MD, PhD
Children's Hospital of Philadelphia
Course Director, Faculty
Nothing to disclose
Mian Umair Ahsan, M.Phil
Research Lab Manager
Children's Hospital of Philadelphia
Faculty
Marisa Bartolomei, PhD
Faculty
Zachary Berlant, MD
CHOP
Faculty
Monica Bertoletti
AIBWS ODV
Italy
Faculty
Jack Brzezinski, MD
The Hospital for Sick Children
Faculty
Diana Carli, MD
Faculty
Faculty Photos
Christopher Cielo, DO
Children's Hospital of Philadelphia
Faculty
Richard Davidson, MD
Children's Hospital of Philadelphia
Faculty
Laura Davis, MD
CHOP
Faculty
Diva De Leon, MD
Children's Hospital of Philadelphia
Faculty
Christopher Eskew
UpdatePromise
Faculty
Arupa Ganguly, PhD
Faculty
Andrew M George, B.S.
Clinical Research Assistant
Children's Hospital of Philadelphia
Faculty
Nothing to disclose
Carlyn Glatts, MD
CHOP
Faculty
Nothing to disclose
Allison C Hu, MD
Research Fellow
Children's Hospital of Philadelphia
Faculty
Sanam Kavari
CHOP
Faculty
Nothing to disclose
Karen Kilson, MSW, Advanced Practice Level 1 Social Worker
Social Worker
Children's Hospital of Philadelphia
Faculty
Nothing to disclose
Cynthia Kropp, LCSW, Social Worker
Social Worker
CHOP
Faculty
Nothing to disclose
Cassandra Ligh, MD
Attending surgeon
Children's Hospital of Philadelphia
Faculty
Suzanne MacFarland, MD
Faculty
Michela M Mansfield, CRNP, CPNP
Nurse Practitioner
CHOP
Faculty
Alessandro Mussa
Faculty
Hyun-Duck Nah-Cederquist, DMD
Children's Hospital of Philadelphia
Faculty
Salima Nesbitt, BSN
CHOP
Faculty
Nothing to disclose
Snehal Nirgude, PhD
Children's Hospital of Philadelphia
Faculty
Nothing to disclose
Rachel Ottman, BA
Research NTP
Widener University
Faculty
Bruce R Pawel, MD
Keck School of Medicine of USC
Faculty
Nothing to disclose
Giuseppe Reynolds, MD
University of Torino, Italy
Italy
Faculty
Nothing to disclose
Dominic Romeo, MS, MTS
Perelman School of Medicine
Faculty
Makaela Somma, MS CCC-SLP
Speech-Language Pathologist
Children's Hospital of Philadelphia
Faculty
Nothing to disclose
Jesse Taylor, MD
Children's Hospital of Philadelphia
Faculty
Elisia D. Tichy, PhD
Research Associate
Children's Hospital of Philadelphia
Faculty
Nothing to disclose
Aravind Viswanathan

Faculty
Kristin Zelley, MS, LCGC
Children's Hospital of Philadelphia
Faculty
Nothing to disclose
Abigail Casalnova, APRN, MSN, CRNP, CPNP-PC
Certified Registered Nurse Practitioner
CHOP
Faculty, Other Planning Committee Member
Nothing to disclose
Alexander Kaplan
Children's Hospital of Philadelphia
Faculty, Other Planning Committee Member
Nothing to disclose

Friday, July 18, 2025
Registration
5:00PM - 6:00PM

Opening Reception and Welcome Remarks
6:00PM - 6:30PM
Jennifer Kalish, MD, PhD

Dinner
6:30PM - 7:30PM

Saturday, July 19, 2025
Registration and Breakfast
8:00AM - 9:00AM

Introduction to BWSp and Clinical Features
9:00AM - 9:30AM
Jennifer Kalish, MD, PhD

A Historic Case Review: The Original BWSp Slides
9:30AM - 9:45AM
Bruce R Pawel, MD

Molecular Aspects of BWSp
9:45AM - 10:00AM
Arupa Ganguly, PhD

Tumor Screening in BWSp
10:00AM - 10:15AM
Suzanne MacFarland, MD
Kristin Zelley, MS, LCGC

Q&A
10:15AM - 10:30AM

Break
10:30AM - 11:00AM

BWSp Experts Panel Discussion - This session is not eligible for credit
11:00AM - 12:00PM
Christopher Cielo, DO
Richard Davidson, MD
Diva De Leon, MD
Hyun-Duck Nah-Cederquist, DMD
Jesse Taylor, MD
Michela M Mansfield, CRNP, CPNP
Cassandra Ligh, MD

Lunch
12:00PM - 1:00PM

Speech Development in BWSp
1:00PM - 1:15PM
Makaela Somma, MS CCC-SLP

BWSp and Development
1:15PM - 1:30PM
Carlyn Glatts, MD

Post-traumatic Stress and Post-traumatic Growth in Caregivers of Children with Beckwith-Wiedemann Spectrum: The Roles of Appraisal and Coping
1:30PM - 1:45PM
Rachel Ottman, BA

Resources for Families
1:45PM - 2:00PM
Karen Kilson, MSW, Advanced Practice Level 1 Social Worker
Cynthia Kropp, LCSW, Social Worker

Q&A
2:00PM - 2:15PM

Break
2:15PM - 2:30PM

Allele-Specific Methylation Analysis Using Oxford Nanopore Sequencing
2:30PM - 2:45PM
Mian Umair Ahsan, M.Phil

Updates on Macroglossia Research
2:45PM - 3:00PM
Jennifer Kalish, MD, PhD
Andrew M George, B.S.
Aravind Viswanathan
Dominic Romeo, MS, MTS
Allison C Hu, MD

Growth Charts for BWSp
3:00PM - 3:15PM
Jennifer Kalish, MD, PhD

An Approach to Lateralized Overgrowth
3:15PM - 3:30PM
Alessandro Mussa

Updates on Tumor Screening Guidelines
3:30PM - 3:45PM
Jennifer Kalish, MD, PhD
Zachary Berlant, MD

The Use of Total Body Densitometry in the Study of Body Composition in BWSp
3:45PM - 4:00PM
Giuseppe Reynolds, MD

Distinctive Clinical and Biological Features of Adrenocortical Tumors in BWSp
4:00PM - 4:15PM
Diana Carli, MD

Q&A
4:15PM - 4:30PM

Blood Tests for Wilms Tumor Surveillance in Children with BWSp
4:30PM - 4:45PM
Jack Brzezinski, MD

BWSp in Animal Models
4:45PM - 5:00PM
Marisa Bartolomei, PhD

The Placenta in BWS: Clinical Associations and Molecular Mechanisms
5:00PM - 5:15PM
Sanam Kavari

Single-nuclei Sequencing Reveals Metabolic Nature of BWSp Liver
5:15PM - 5:30PM
Snehal Nirgude, PhD

A Taste of Tongue Overgrowth in BWSp
5:30PM - 5:45PM
Elisia D. Tichy, PhD

Assessing Focal Liver Lesions in Beckwith-Wiedemann Syndrome
5:45PM - 6:00PM
Laura Davis, MD

Q&A
6:00PM - 6:15PM

Closing Remarks
6:15PM - 6:30PM
Jennifer Kalish, MD, PhD

Dinner
6:30PM - 7:30PM

Sunday, July 20, 2025
Breakfast
8:00AM - 9:00AM

BWSp Through the Years: Parent Perspectives
9:00AM - 9:40AM

Q&A
9:40AM - 10:00AM

BWSp and Development
10:00AM - 10:45AM

BWSp in Adults
10:00AM - 10:45AM

Macroglossia
10:00AM - 10:45AM

Tumor Screening in BWSp
10:00AM - 10:45AM

Break
10:45AM - 11:00AM

American Beckwith-Wiedemann Spectrum Family Foundation
11:00AM - 11:20AM
Christopher Eskew

Next Steps in BWSp Research
11:20AM - 11:30AM
Jennifer Kalish, MD, PhD

Conference Adjourns
11:30AM - 11:40AM

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