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7th Annual CHOP Immune Dysregulation Symposium Rub Some DIRT In It: An Immune Dysregulation Approach to Infection

  • Overview
  • Faculty
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Add to Calendar 7th Annual CHOP Immune Dysregulation Symposium Rub Some DIRT In It: An Immune Dysregulation Approach to Infection 4/30/2025 8:00:00 AM 4/30/2025 5:00:00 PM America/New_York For More Details: https://chop.cloud-cme.com/course/courseoverview?EID=11107 Description: This symposium hosted by the CHOP Multidisciplinary Immune Dysregulation Team is intended for clinicians, researchers, and those who care for patients with complex multiorgan immune disease. It precedes the Clinical Immunology Society meeting in Philadelphia to synergize with common activities and themes. This symposium will explore immune dysregulation driven by infection. The symposium will review kno... Children's Hospital of Philadelphia false MM/DD/YYYY


Date & Location
Wednesday, April 30, 2025, 8:00 AM - 5:00 PM, Children's Hospital of Philadelphia

Overview

This symposium hosted by the CHOP Multidisciplinary Immune Dysregulation Team is intended for clinicians, researchers, and those who care for patients with complex multiorgan immune disease. It precedes the Clinical Immunology Society meeting in Philadelphia to synergize with common activities and themes. This symposium will explore immune dysregulation driven by infection. The symposium will review knowledge on disease pathogenesis and best practices for therapeutics. The event will include cutting edge talks, a debate on therapeutic decision-making, provocative cases, and more. Keynote speakers include:

  • Jeffrey I. Cohen, MD - Chief of Laboratory of Infectious Disease and of the Medical Virology Section at the National Institutes of Health.

  • Manish Butte, MD, PhD - Division Chief of Immunology, Allergy, and Rheumatology. Professor with tenure in the Department of Pediatrics at University of California Los Angeles.

  • Carolina Lopez, PhD - Professor of Environmental Medicine and BJC Investigator in the Department of Molecular Microbiology at the Washington University School of Medicine in St. Louis.


Registration
REGISTRATION IS FREE
Attending the conference in person includes continental breakfast, refreshments, lunch, and course materials.

Attending the conference virtually includes livestream access to the conference and access to view online course materials.



Mitigation of Relevant Financial Relationships


Children's Hospital of Philadelphia adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Member Information
Role in activity
Nature of Relationship(s) / Name of Ineligible Company(s)
Hamid Bassiri, MD, PhD
Assistant Professor
Children's Hospital of Philadelphia
Faculty
Paid consultant-Guidepoint Consulting (Relationship has ended)|Employment-Johnson and Johnson|Paid consultant-FirstThought Consulting (Relationship has ended)|Consulting Fee-Kriya Therapeutics (Relationship has ended)|Honoraria-American College of Rheumatology (Relationship has ended)
Edward Behrens, MD
MD
Chop
Faculty
Elise Breed, MD, PhD
Faculty
Manish Butte, MD, PhD
UCLA Health
Faculty
Scott Canna, MD
MD
CHOP
Faculty
Hallie A Carol, MD
Rheumatology Fellow
CHOP
Faculty
Jeffrey Cohen, MD
NIH
Faculty
Hana Conlon, CRNP
CRNP
Children's Hospital of Philadelphia
Faculty
Nothing to disclose
Brian Fisher, DO
DO
The Children's Hospital of Philadelphia
Faculty
Vinchelle Hardison, MD
Faculty
Scott Hensley, PhD
Faculty
Audrey R John, MD, PhD
Chief, Infectious Diseases
Children's Hospital of Philadelphia
Faculty
Jonathan Kotzin, MD, PhD
University of Pennsylvania
Faculty
Dorottya Laczko, MD, PhD
Faculty
Michele Lambert, MD
Children's Hospital of Philadelphia
Faculty
Honoraria-Novartis AG|Grant or research support-Novartis AG|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Dova, Octapharma, Rigel, Argenx, Principia|Honoraria-Dova, Octapharma, Rigel, Argenx, Shionogi, Principia|Grant or research support-Dova, Octapharma, Rigel, Argenx, Principia|Membership on Advisory Committees or Review Panels, Board Membership, etc.-PDSA, 22qSociety, CDLS Foundation
Robert B Lindell, MD
Children's Hospital of Philadelphia
Faculty
Nothing to disclose
Carolina Lopez, PhD
Washington University, St. Louis
Faculty
Adam Mayer, MD
Faculty
Whitney Petrosa, CRNP
CRNP
The Children's Hospital of Philadelphia
Faculty
Paul J Planet, MD, PhD
Asst. Professor
Children's Hospital of Philadelphia
Faculty
Irini Sereti, MD, PhD
NIH
Faculty
Michael silverman, MD, PhD
Faculty
Kathleen Sullivan, MD PhD
Chop
Faculty
David Teachey, MD
MD
CHOP
Faculty
Laura Vella, MD
MD
Faculty

Wednesday, April 30, 2025

Breakfast and Registration
8:00AM - 8:30AM
Complement Dysfunction Correlates with Pediatric Severe Dengue
8:30AM - 8:50AM
Edward Behrens, MD
Influenza Virus Immunity
8:50AM - 9:10AM
Scott Hensley, PhD
KEYNOTE: EBV and Immune Dysregulation: Damage from Friendly Fire
9:10AM - 9:45AM
Jeffrey Cohen, MD
Break
9:45AM - 10:05AM
KEYNOTE: The Perils and Pitfalls of Advanced HIV Disease: From Bedside to Bench
10:05AM - 10:40AM
Irini Sereti, MD, PhD
Leveraging Early-life Commensal Microbes to Improve Immune Health
10:40AM - 11:00AM
Michael silverman, MD, PhD
A Novel Hyperferritinemia Screen to Aid Differentiation of Hyperinflammatory Disorders
11:00AM - 11:20AM
Hallie A Carol, MD
Sepsis Heterogeneity: Risk Stratification and Precision Therapeutic
11:20AM - 11:40AM
Robert B Lindell, MD
KEYNOTE: Modulating Type 2 Immune Dysregulation to Treat Infections
11:40AM - 12:15PM
Manish Butte, MD, PhD
Lunch
12:15PM - 1:05PM
Out of the Mouths of Babes: “Breath-omics” to Interrogate Pediatric Health and Disease
1:05PM - 1:20PM
Audrey R John, MD, PhD
Recognizing the Importance of Host-Microbe Interface with I2DRI
1:20PM - 1:35PM
Audrey R John, MD, PhD
Adults DIRT too – Lessons from a Difficult Case of Systemic Inflammation
1:35PM - 1:55PM
Jonathan Kotzin, MD, PhD
Fever of Unknown Origin: A Case that Breaks the Mold
1:55PM - 2:15PM
Adam Mayer, MD
Ticked Off: The Unexpected Journey to Immune Overdrive
2:15PM - 2:35PM
Vinchelle Hardison, MD
Break
2:35PM - 2:50PM
Debate: Next Generation Sequencing in Infection Diagnosis
2:50PM - 3:35PM
Brian Fisher, DO
Paul J Planet, MD, PhD
KEYNOTE: Long-term Consequences of Parainfluenza Virus Infection
3:35PM - 4:25PM
Carolina Lopez, PhD
Closing Remarks
4:25PM - 4:40PM
Edward Behrens, MD


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