OMB No. 0925-0001 and 0925-0002 (Rev. 10/2021 Approved Through 09/30/2024)
BIOGRAPHICAL SKETCH
Provide the following information for the Senior/key personnel and other significant contributors.
Follow this format for each person. DO NOT EXCEED FIVE PAGES.
NAME: María V. Fraga, MD
eRA COMMONS USER NAME (credential, e.g., agency login):
POSITION TITLE: Associate Professor of Clinical Pediatrics
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)
INSTITUTION AND LOCATION | DEGREE (if applicable) | Completion Date MM/YYYY | FIELD OF STUDY |
University of Buenos Aires Medical School | MD | 06/99 | Medicine |
The Children’s Hospital of Buenos Aires | Residency | 06/04 | Pediatrics |
National Pediatric Hospital of Buenos Aires | Fellowship | 6/05 | Neonatology |
Albert Einstein Medical Center, Phila PA | Residency | 6/08 | Pediatrics |
The Children’s Hospital of Philadelphia | Fellowship | 6/11 | Neonatology |
A. Personal Statement
I am a Professor of Clinical Pediatrics and an attending neonatologist physician at the Children’s Hospital of Philadelphia with an interest in the bedside assessment of neonatal cardiac hemodynamics and in procedural and diagnostic point-of-care ultrasound. I have completed my training on functional neonatal echocardiography as well as different Point-of-Care Ultrasound applications. Furthermore, I have developed the “Clinician Performed Ultrasound Program” in the Neonatal Intensive Care Unit at The Children’s Hospital of Philadelphia for which I am currently the director and have been teaching in Ultrasound courses nationwide as well as internationally. Since 2015 I have been the co-director of the CHOP Bedside Ultrasound Course, offering multi-discipline training in pediatric and neonatal procedural and diagnostic ultrasound applications.
Since 2014 I have been the PI for multicenter studies which have given me the experience in conducting clinical research in critically ill infants. I am currently the site PI for a multicenter pilot trial “Milrinone in Congenital Diaphragmatic Hernia” sponsored by the NICHD through the Neonatal Research Network (NRN). My specific area of interest include education in Point-of-Care Ultrasound and neonatal hemodynamics to improve patient care.
Citations:
- Fraga MV, Stoller JZ, Lorch SA: Novel Technologies for Neonatal Care: The Case of Point-of-Care Lung Ultrasonography. Pediatrics 142(3), September 2018 Notes: DOI: 10.1542/peds.2018-1621. Epub 2018 Aug 14.
- Giesinger RE, Stanford AH, Rios DR, Bhombal S, Fraga MV, Levy VY, McNamara PJ; United States Hemodynamics Collaborative: Targeted neonatal echocardiography in the United States of America: the contemporary perspective and challenges to implementation. Pediatr Res Page: online, February 2019 Notes: DOI: 10.1038/s41390-019-0338-3. Epub ahead of print.
- Fraga MV, Dysart KC, Rintoul N, Chaudhary AS, Ratcliffe SJ, Fedic A, Kren S, Cohen MS, Kirpalani H: Cardiac output measurement using the Ultrasonic Cardiac Output Monitor: A validation study in newborn infants. Neonatology Page: online, July 2019 Notes: DOI: 10.1159/000501005. Published online July 19, 2019.
- Gaulton JS, Mercer-Rosa LM, Glatz AC, Jensen EA, Capone V, Scott C, Appel SM, Stoller JZ, Fraga MV: Relationship between pulmonary artery acceleration time and pulmonary artery pressures in infants. Echocardiography 36(8): 1524-1531, August 2019 Notes: DOI: 10.1111/echo.14430. Published online July 1, 2019
B. Positions, Scientific Appointments, and Honors
Positions
2011-2017 Assistant Professor of Clinical Pediatrics, University of Pennsylvania School of Medicine
2017-present Associate Professor of Clinical Pediatrics, University of Pennsylvania School of Medicine
2011-present Attending Neonatologist, The Children’s Hospital of Philadelphia
Honors
1999 Honor Diploma, University of Buenos Aires Medical School
2011 Henle Chair Award, Research Proposal “Cardiac Output Measurement in neonates Using the Ultrasound Cardiac Output Monitor (USCOM):A Validation Study in Newborn Infants”.
2016 Named to the 2015-2016 Early Career Faculty Honor Roll by the Senior Resident Graduating Class on June 1, 2016 at The Children's Hospital of Philadelphia, Philadelphia, PA
2017 Named to the 2016-2017 Early Career Faculty Honor Roll by the Senior Resident Graduating Class on June 7, 2017 at Children's Hospital of Philadelphia, Philadelphia, PA
2021 Department of Pediatrics Alan R. Cohen Master Clinician Award 2021, Children’s Hospital of Philadelphia
2021 Presidential Citation, Society of Critical Care Medicine
C. Contributions to Science
1. My early publications directly addressed the importance and accuracy if non-invasive hemodynamic monitoring methods. In collaboration with my colleagues we published the following manuscripts:
a. Fraga MV, Dysart KC, Rintoul N, Chaudhary AS, Ratcliffe SJ, Fedic A, Kren S, Cohen MS, Kirpalani H: Cardiac output measurement using the Ultrasonic Cardiac Output Monitor: A validation study in newborn infants. Neonatology Page: online, July 2019 Notes: DOI: 10.1159/000501005. Published online July 19, 2019.
b. Ansems S, Kirpalani H, Mercer-Rosa L, Wang Y, Hopper RK, Fraga MV, Jensen EA: Patent Ductus Arteriosus and the Effects of its late Closure in Preterm Infants with severe Bronchopulmonary Dysplasia. Neonatology Page: online, July 2019.
c. Gaulton JS, Mercer-Rosa LM, Glatz AC, Jensen EA, Capone V, Scott C, Appel SM, Stoller JZ, Fraga MV: Relationship between pulmonary artery acceleration time and pulmonary artery pressures in infants. Echocardiography 36(8): 1524-1531, August 2019 Notes: DOI: 10.1111/echo.14430. Published online July 1, 2019.
d. Pawlowski TW, Stoller JZ, Rintoul NE, Hedrick HL, Quartermain MD, Fraga MV: Point-of-care ultrasound for the evaluation of venous cannula position in neonatal extracorporeal membrane oxygenation. J Perinatol April 2021 Notes: doi: 10.1038/s41372-021-00936-8.
2. In addition to the contributions described above, later I focused not only on neonatal hemodynamics but also on the use of Point-of-Care ultrasound for many different applications as shown in the following publications:
- Conlon TW, Nishisaki A, Singh Y, Bhombal S, De Luca D, Kessler DO, Su ER, Chen AE, Fraga MV: Moving Beyond the Stethoscope: Diagnostic Point-of-Care Ultrasound in Pediatric Practice. Pediatrics Page: online, September 2019 Notes: DOI: 10.1542/peds.2019-1402. Published online September 3, 2019.
- Fraga MV, Stoller JZ, Glau CL, De Luca D, Rempell RG, Wengler JL, Yek Kee C, Muhly WT, Boretsky K, Conlon TW: Seeing Is Believing: Ultrasound in Pediatric Procedural Performance. Pediatrics. (eds.). American Academy of Pediatrics, 144(5): online, October 2019 Notes: DOI: 10.1542/peds.2019-1401. Published online October 15, 2019.
- Miller L, Stoller J, Fraga MV: "Point-of-care ultrasound in the neonatal ICU" Current Opinion in Pediatrics 31(00), December 2019 Notes: Online DOI:10.1097/MOP.0000000000000863.
- Singh Yogen, Tissot Cecile, Fraga María V, Yousef Nadya, Cortes Rafael Gonzalez, Lopez Jorge, Sanchez-de-Toledo Joan, Brierley Joe, Colunga Juan Mayordomo, Raffaj Dusan, Da Cruz Eduardo, Durand Philippe, Kenderessy Peter, Lang Hans-Joerg, Nishisaki Akira, Kneyber Martin C, Tissieres Pierre, Conlon Thomas W, De Luca Daniele: International evidence-based guidelines on Point of Care Ultrasound (POCUS) for critically ill neonates and children issued by the POCUS Working Group of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC). Critical care (London, England) 24(1): 65, Feb 2020.
Complete List of Published Work
https://pubmed.ncbi.nlm.nih.gov/?term=fraga+mv