Joseph W. St. Geme

Page 1

The Perelman School of Medicine at the University of Pennsylvania

Curriculum Vitae

Date Prepared: June 2022

Name:              Joseph W. St. Geme, III, M.D.

Current Position:              Chair of the Department of Pediatrics

The Perelman School of Medicine at the University of Pennsylvania

Chair of the Department of Pediatrics and Physician-in-Chief

Children’s Hospital of Philadelphia

Primary Academic Appointment:              Leonard and Madlyn Abramson Professor of Pediatrics

The Perelman School of Medicine at the University of Pennsylvania

Primary Academic Department:              Department of Pediatrics

The Perelman School of Medicine at the University of Pennsylvania

Secondary Appointment:              Professor of Microbiology

The Perelman School of Medicine at the University of Pennsylvania

Present Academic Rank and Title:              Professor of Pediatrics

Date and Rank of First University of              July 1, 2013, Professor

Pennsylvania Faculty Appointment:             

Medical Licensure:              Missouri License #100619

              California License #G63017

              North Carolina License #2005-00878

              Pennsylvania License #MD034629E

              New Jersey License #25MA09345300

Specialty Certification(s) and Dates:              Diplomate, National Board of Medical Examiners – 1984

              Diplomate, American Board of Pediatrics – 1989

Pediatric Infectious Diseases – 1994, recertified in 2001 and 2008, and currently maintaining certification

Citizen of:              USA

Education:

1975-1979              Stanford University, Stanford, CA              B.S.

1980-1984              Harvard Medical School, Boston, MA              M.D.

Professional Training and Academic Career:

1984-1985              Pediatric Intern, Children's Hospital of Philadelphia

1985-1987              Pediatric Resident, Children's Hospital of Philadelphia

1987-1988              Chief Resident in Pediatrics, Children's Hospital of Philadelphia

1988-1992              Postdoctoral Fellow, Department of Microbiology and Immunology, Stanford University

1991-1992                            Postdoctoral Fellow, Department of Pediatrics, Division of Infectious Diseases, Stanford University

1992-1992              Instructor in Pediatrics and Molecular Microbiology, Washington University School of Medicine, St. Louis, July-September 1992

1992-1997              Assistant Professor of Pediatrics and Molecular Microbiology, Washington University School of Medicine, St. Louis

1995-2005              Director, Fellowship Program in Pediatric Infectious Diseases, Department of Pediatrics, Washington University School of Medicine, St. Louis

1997-2002              Associate Professor of Pediatrics and Molecular Microbiology, Washington University School of Medicine, St. Louis

1998-2005              Director, Division of Infectious Diseases, Department of Pediatrics, Washington University School of Medicine, St. Louis

1999-2005              Unit Leader, Infection, Immunity, and Inflammation Research Unit, Department of Pediatrics, Washington University School of Medicine, St. Louis

2002-2005              Professor of Pediatrics and Molecular Microbiology, Washington University School of Medicine, St. Louis

2005-2013              Professor of Pediatrics with Tenure (Track II) and Chairman of the Department of Pediatrics, Duke University Medical Center, Durham, NC

2005-2103              Professor of Molecular Genetics and Microbiology, Duke University Medical Center

2013-pres              Professor of Pediatrics with Tenure and Chair of the Department of Pediatrics, The Perelman School of Medicine at the University of Pennsylvania

2013-pres              Professor of Microbiology, The Perelman School of Medicine at the University of Pennsylvania

2013-pres              Chair of the Department of Pediatrics and Physician-in-Chief, Children’s Hospital of Philadelphia

2016-pres              President, Children’s Hospital of Philadelphia Practice Association, Children’s Hospital of Philadelphia

2016-pres              President, Medical Staff, Children’s Hospital of Philadelphia

Scholarly Societies:

1979              Phi Beta Kappa, Stanford University Chapter

1987              Alpha Omega Alpha Honor Society, University of Pennsylvania School of Medicine

1985-1988              Member, Pennsylvania Medical Society

1985-pres              Fellow, American Academy of Pediatrics

1989-pres              Member, American Association for the Advancement of Science

1992-pres              Member, American Society for Microbiology

1993-pres              Member, Pediatrics Infectious Diseases Society

1996-pres              Member, Society for Pediatric Research

1998-pres              Member, American Society for Clinical Investigation

1999-pres              Fellow, Infectious Diseases Society of America

2003-pres              Member, American Pediatric Society

2005-2013              Member, North Carolina Pediatric Society

2007-pres              Member, Association of American Physicians

2007-pres              Fellow, American Academy of Microbiology

2010-pres              Member, Institute of Medicine/National Academy of Medicine

2013-pres              Member, Henry Kunkel Society

2014-pres              Fellow, Pediatric Infectious Diseases Society

Professional Awards and Special Recognitions:

1979              Phi Beta Kappa, Stanford University

1979              Graduation with Distinction, Stanford University

1979              First Team College Football Academic All-America

1979              Stanford Varsity Football Nominee for Al Masters Award (scholarship, leadership, and athletic achievement)

1979              Stanford Varsity Football 'Unsung Hero' Award (for unrecognized contribution to Stanford football)

1987              Alpha Omega Alpha Honor Society, University of Pennsylvania School of Medicine

1987              Outstanding Resident Teacher, Children's Hospital of Philadelphia

1987              Award for Resident Humanitarian, Children's Hospital of Philadelphia

1988              Ritter Award for Service as Chief Resident in Pediatrics, Children's Hospital of Philadelphia

1988              Pediatric Scientist Training Program Fellowship Award, Association of Medical School Pediatric Department Chairmen

1990              American Lung Association of California Research Fellowship Award

1993              Infectious Diseases Society of America/Lederle Praxis Biologic Young Investigator Award in Bacterial Vaccine Development

1994              Basil O'Connor Award, March of Dimes Foundation

1995              Attending Teacher of the Year, St. Louis Children's Hospital, Pediatric Residency Program

1996              Pediatric Infectious Diseases Society Young Investigator Award

1997              American Heart Association, Established Investigator Award

1998              Attending Teacher of the Year, St. Louis Children's Hospital, Pediatric Residency Program

1998              Squibb Award, Infectious Diseases Society of America

1998              American Society for Clinical Investigation

2001              Clinical Teacher of the Year, Washington University School of Medicine Class of 2002

2002              Clinical Teacher of the Year, Washington University School of Medicine Class of 2003

2003              Clinical Teacher of the Year, Washington University School of Medicine Class of 2004

2005              Outstanding Mentor Award, Washington University School of Medicine

2005              Specialty Attending Teacher of the Year, St. Louis Children’s Hospital, Pediatric Residency Program

2005              Best Doctors in America

2006              Samuel Katz Faculty Teaching Award, Duke University Medical Center, Pediatric Residency Program

2006              Best Doctors in America

2006              Lewis Wannamaker Memorial Lecture, University of Minnesota

2006              Harris D. Riley Lecture, University of Oklahoma Department of Pediatrics

2007              Norman Kretchmer Memorial Lecture, Stanford University Department of Pediatrics

2007              Association of American Physicians

2007              James B. Duke Professorship, Duke University

2007              American Academy of Microbiology

2007              Samuel Katz Faculty Teaching Award, Duke University Medical Center, Pediatric Residency Program

2007              Best Doctors in America

2008              Joseph W. St. Geme, Jr. Memorial Lecture, University of Colorado

2008              Best Doctors in America

2009              Best Doctors in America

2009              Fellow, American Association for the Advancement of Science

2010              Best Doctors in America

2010              Institute of Medicine (now National Academy of Medicine)

2011              Distinguished Service Award, Pediatric Infectious Diseases Society

2011              Best Doctors in America

2012               Elia Ayoub Memorial Lecture, University of Florida

2012              Best Doctors in America

2013              Best Doctors in America

2013              Cannon Eley Lecture, Boston Children’s Hospital

2013              Leonard and Madlyn Abramson Professorship, The Children’s Hospital of Philadelphia

2013              Henry Kunkel Society

2014              Best Doctors in America

2014              Lawrence G. Crowley Distinguished Lecture in Pediatrics, Stanford University

2015              Best Doctors in America

2016              Hattie Alexander Memorial Lecture, Columbia University

2016              Best Doctors in America

2017              Best Doctors in America

2018              Best Doctors in America

2019              Luminary in Pediatric Infectious Diseases Lecture, St. Jude Children’s Research Hospital

2019              Donald Thurston Lecture in Pediatrics, Washington University

2019              Best Doctors in America

2020              Federation of Pediatric Organizations Joseph W. St. Geme, Jr. Leadership Award

2020              Best Doctors in America

2021              Saul Krugman Memorial Lecture, New York University

2021              Best Doctors in America

2022              Christian R. and Mary F. Lindback Distinguished Teaching Award, University of Pennsylvania

Organizations and Participation:

University, Department, and Hospital

1981-1984              Committee on Continuing Medical Education, Harvard Medical School

1981-1984              Student-Faculty Committee, Harvard Medical School

1985-1988              Graduate Education Committee, Children's Hospital of Philadelphia

1986-1988              Residency Selection Committee, Children's Hospital of Philadelphia

1987-1988              Executive Council of Medical Staff, Children's Hospital of Philadelphia

1987-1988              Education Committee, Children's Hospital of Philadelphia

1987-1988              Undergraduate Medical Education Committee, Children's Hospital of Philadelphia

1993-1995              Junior Faculty Advisory Committee, Department of Pediatrics, Washington University School of Medicine

1993-1995              Residency Education Committee, Department of Pediatrics, Washington University School of Medicine

1994-1999              PL-1 Advisory Committee, Department of Pediatrics, Washington University School of Medicine

1995-1996              Research Space Utilization Committee, Department of Pediatrics, Washington University School of Medicine

1995-1996              Reengineering Committee/Patient Aggregation Design Team, St. Louis Children's Hospital

1995-1997              Markey Program in Pathobiology, Washington University School of Medicine, Clinical Mentor

1995-2005              Graduate Medical Education Fellowship Committee, Washington University School of Medicine

1996-2000              Fellowship Committee, Department of Pediatrics, Washington University School of Medicine

1997-2005              PL-1 Selection Committee, Department of Pediatrics, Washington University School of Medicine

1998-2005              Medical Scientist Training Program, Washington University School of Medicine, Clinical Mentor

1999-2000              Research Building Planning Committee, Department of Pediatrics, Washington University School of Medicine

1999-2005              Website Committee (Chairman), Department of Pediatrics, Washington University School of Medicine

2000-2003              Fellows as Attendings Committee, St. Louis Children's Hospital

2000-2005              Institutional Biological and Chemical Safety Committee, Washington University School of Medicine

2001              E-Health Strategy Group, St. Louis Children's Hospital

2001-2003              Division of Biology and Biomedical Sciences Internal Review Committee, Washington University

2001-2004              Quality Committee of the Board of Trustees, St. Louis Children's Hospital

2001-2004              Patient Safety Subcommittee of the Quality Committee of the Board of Trustees (Co-Chairman), St. Louis Children's Hospital

2001-2005              Automated Curriculum Vitae Committee (Chairman), Department of Pediatrics, Washington University School of Medicine

2002-2003              Division of Biology and Biomedical Sciences Internal Review, Student Subcommittee, Washington University

2002-2005              Child Health Advocacy and Outreach, Physician Advisory Panel, St. Louis Children's Hospital

2003-2005              Steering Committee, Program in Molecular Microbiology and Microbial Pathogenesis, Division of Biology and Biological Sciences, Washington University

2003-2005              Steering Committee, Infectious Diseases Scholars Program, Washington University

2003-2005              Infectious Diseases Scholars Program, Washington University, Clinical Mentor

2004-2005              Information Systems Oversight Committee (Chairman), Department of Pediatrics, Washington University School of Medicine

2004-2005              Education subcommittee (Work Rounds on the General Pediatrics Wards) (Chairman), Department of Pediatrics, Washington University School of Medicine

2004-2005              Information Management Strategic Planning Committee, St. Louis Children’s Hospital

2005-2013              Executive Committee for the Medical Staff (ECMS), Duke University Medical Center

2005-2013              Medical Center Executive Committee (MCEC), Duke University Medical Center

2005-2013              Private Diagnostic Clinic (PDC) Administrative Board, Duke University Medial Center

2005-2013              Private Diagnostic Clinic (PDC) Clinical Affairs Committee, Duke University Medical Center

2005-2013              Duke Clinical Research Institute (DCRI) Internal Advisory Board, Duke University Medical Center

2005-2013              Duke Children’s National Board of Advisors, Duke University Medical Center

2005-2013              Duke Regional Biocontainment Laboratory Scientific Advisory Board, Duke University Medical Center

2005-2013              DukeMed Magazine Advisory Board, Duke University Medical Center

2006-2013              Bridge Funding Committee (Chairman), Duke University School of Medicine

2007              Search Committee for Dean of Duke University School of Medicine (Chairman)

2007              Committee on Faculty Development, Duke University School of Medicine

2007-2011              Executive Steering Committee for Major Hospital Expansion and Cancer Center, Duke University Health System

2007-2013              Science Advisory Council, Duke University School of Medicine

2007-2013              Microbial Pathogenesis, Emerging Infections, and Host Defense Steering Committee (Chairman), Duke University School of Medicine

2008-2009              Search Committee for Chair of the Department of Medicine, Duke University Medical Center (Chairman)

2010-2011              Committee on the Review of Appointment, Promotions, and Tenure Criteria, Duke University Medical Center

2010-2011              Search Committee for Vice Chancellor for Development and Alumni Affairs, Duke University Medical Center

2010-2011              Search Committee for Chief of the Division of Child and Adolescent Psychiatry, Duke University Medical Center

2010-2013              Duke Translational Research Institute (DTRI) Internal Advisory Board, Duke University Medical Center

2011-2012              Search Committee for Director of the Clinical Microbiology Laboratory, Duke University Hospital

2012-2013              Enterprise Wide Planning Process, Optimizing Research Committee, Duke University Medical Center (Co-Chairman)

2012-2013              Enterprise Wide Planning Process, Steering Committee, Duke University Medical Center

2013-pres              Academic Steering Committee, Perelman School of Medicine at the University of Pennsylvania

2013-pres              Standing Committee of Department Chairs and Center and Institute Directors, Perelman School of Medicine at the University of Pennsylvania

2013-pres              Chief Executive Officer Council, Children’s Hospital of Philadelphia

2013-pres              Enterprise Steering and Risk Committee, Children’s Hospital of Philadelphia

2013-pres              Children’s Hospital of Philadelphia Practice Association Executive Committee, Children’s Hospital of Philadelphia

2013-pres              Department Chairs Committee, Children’s Hospital of Philadelphia

2013-pres              Executive Committee of the Medical Staff, Children’s Hospital of Philadelphia

2013-pres              Board of Trustees, Children’s Hospital of Philadelphia

2014-2015              Search Committee for Chair of the Department of Microbiology, Perelman School of Medicine at the University of Pennsylvania

2014-2017              Advisory Committee, Robert Wood Johnson Clinical Scholars Program, Perelman School of Medicine at the University of Pennsylvania

2014-pres              Advisory Committee, Microbiome Initiative, Perelman School of Medicine at the University of Pennsylvania and Children’s Hospital of Philadelphia

2014-pres              Advisory Board and Steering Committee, Orphan Diseases Center, Perelman School of Medicine at the University of Pennsylvania

2014-pres              Internal Advisory Committee of the March of Dimes Prematurity Research Center at the University of Pennsylvania

2015              Search Committee for Chief Operating Officer, Children’s Hospital of Philadelphia

2015-pres              Research Council, Children’s Hospital of Philadelphia (Co-Chairman)

2015-pres              Internal Advisory Committee, Center for Healthcare Improvement and Patient Safety at the Perelman School of Medicine at the University of Pennsylvania

2015-pres              Frontier Programs Oversight Panel, Children’s Hospital of Philadelphia (Chairman)

2015-pres              Internal Advisory Board, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine at the University of Pennsylvania

2016-pres              Internal Advisory Board, Center for AIDS Research, Perelman School of Medicine at the University of Pennsylvania

2016-pres              Advisory Committee, National Clinician Scholars Program, the University of Pennsylvania

2016-pres              Children’s Hospital of Philadelphia Practice Association Executive Committee, Children’s Hospital of Philadelphia (Chair)

2016-2019              Scale Committee, Children’s Hospital of Philadelphia (Co-Chairman)

2016-pres              President, Medical Staff, Children’s Hospital of Philadelphia

2018-pres              National Growth Strategy Steering Committee, Children’s Hospital of Philadelphia

2018-pres              Major Facility Projects Subcommittee, Children’s Hospital of Philadelphia

2018-pres              Physician and Administrative Office Building Executive Sponsor, Children’s Hospital of Philadelphia

2019-pres              Cell and Gene Therapy Collaborative, Steering Committee (Co-Chairman)

2019-pres              Executive Council of the Medical Scientist Training Program, Perelman School of Medicine at the University of Pennsylvania

2019-pres              Joint Clinical Operations Committee, Children’s Hospital of Philadelphia (Co-Chairman)

2020-pres              Clinical Operations Leadership Committee (Co-Chairman)

2020-pres              Omics and Big Data Initiative, Coordinating Committee (Co-Chairman)

2021-pres              Post-Acute Care, Steering Committee

National and International

1996              Bacteriology & Mycology Study Section 2, Ad Hoc Member, NIH NIAID

1997              Bacteriology & Mycology Study Section 1, Ad Hoc Member, NIH NIAID

1998-2000              Long-range Strategic Planning Committee, Pediatric Infectious Diseases Society

1998-2005              Program Committee, Pediatric Infectious Diseases Society

1999              Ad Hoc Research Grant Reviewer, Netherlands Asthma Foundation

1999              Ad Hoc Research Grant Reviewer, The Wellcome Trust

1999-2000              Annual Meeting Study Group, American Pediatric Society and Society for Pediatric Research

1999-2002              Program Committee, Annual Meeting of the Infectious Diseases Society of America

1999-2005              Research Affairs Committee (Chairman), Pediatric Infectious Diseases Society

1999-2008              Council Member, Pediatric Infectious Diseases Society

1999-Pres              Co-Director and Chairman of Selection Committee, PIDS-St. Jude Fellowship Program in Basic Research

2000              Scientific Organizing Committee for the Merieux Foundation International Symposium on "Otitis media: A preventable disease?"

2001              Ad Hoc Grant Reviewer, March of Dimes, Basil O'Connor Program

2001-2002              National Board of Medical Examiners, USMLE Step 1 Microbiology Committee

2001-2003              Secretary-Treasurer, Pediatric Infectious Diseases Society

2001-2006              External Advisory Board, University of California at Los Angeles Department of Pediatrics, NIH Child Health Research Center of Excellence

2002              Ad Hoc Grant Reviewer, NIH, National Institute of Allergy and Infectious Diseases

2002-2003              Nominations Committee, Society for Pediatric Research

2003              Scientific Advisory Committee, 8th International Symposium on Recent Advances in Otitis Media

2003              External Advisory Committee, Division of Pediatric Infectious Diseases, Northwestern University School of Medicine, Children's Memorial Hospital

2003-2005              President-Elect, Pediatric Infectious Diseases Society

2003-2005              External Advisory Board, Duke University Department of Pediatrics, NIH Child Health Research Center of Excellence

2003-2005              External Advisory Board, Duke University Department of Pediatrics, NIH National Institute of Child Health and Human Development Fellowship Training Program

2003-2005              Research Committee, Infectious Diseases Society of America, Liaison to Pediatric Infectious Diseases Society

2003-2005              Student and House Officer Research Awards Committee, Society for Pediatric Research

2003-2006              Council Member, Society for Pediatric Research

2003-2009              Research Awards Committee, Infectious Diseases Society of America

2004              Ad Hoc Grant Reviewer, NIH, National Institutes of Deafness and Other Communication Disorders

2004              Ad Hoc Grant Reviewer, NIH, National Institutes of Allergy and Infectious Diseases

2005-2007              President, Pediatric Infectious Diseases Society

2006-2016              Subspecialties Committee, American Board of Pediatrics

2007              Award Nominations Committee, American Pediatric Society

2007              Scientific Advisory Committee, 9th International Symposium on Recent Advances in Otitis Media

2007-2009              Past President, Pediatric Infectious Diseases Society

2007-2009              Pediatric Infectious Diseases Society Liaison to the Infectious Diseases Society of America Board of Directors

2007-2009              President, Pediatric Infectious Diseases Society Research and Education Foundation

2007-2009              Board Member, World Society in Pediatric Infectious Diseases

2007-2013              Advisory Committee, Burroughs Wellcome Fund, Investigators in the Pathogenesis of Infectious Disease Program

2007-pres              Selection Committee, Pediatric Scientist Development Program

2007-2016              Research Advisory Committee, American Board of Pediatrics

2008-2009              Scientific Advisory Committee, World Congress of Pediatric Infectious Diseases

2008-2009              Nominations Committee, Society for Pediatric Research

2008-2013              Southeast Regional Center of Excellence in Emerging Infections and Biodefense (SERCEB) Steering Committee

2009-2011              Nominations Committee, American Pediatric Society

2009-2016              Board of Directors, American Board of Pediatrics

2009-2016              Board of Directors, American Board of Pediatrics Foundation

2010              Ad Hoc Grant Reviewer, Communications Disorders Review Committee, NIH, National Institutes of Deafness and Other Communication Disorders

2010-pres              External Advisory Board, Oregon Health and Science University Department of Pediatrics Research Program

2010-pres              Finance Committee, Pediatric Infectious Diseases Society

2010-pres              Development Committee, Pediatric Infectious Diseases Society

2011-2012              Institute of Medicine Committee on Best Pharmaceutical for Children Act and Pediatric Research Equity Act

2011-2012              Fellowship Endowment Task Force, Pediatric Infectious Diseases Society

2011-2013              Subspecialties Task Force, American Board of Pediatrics

2011-2016              Finance Committee (Chair), American Board of Pediatrics

2012              Ad Hoc Grant Reviewer, NIH, National Institute of Deafness and Other Communication Disorders

2012-2013              Committee on Diversity and Inclusion, Visioning Summit, Federation of Pediatric Organizations

2013              Secretary-Treasurer, American Board of Pediatrics

2013              Audit Committee (Chair), American Board of Pediatrics

2013-pres              External Advisory Committee, The University of California at Los Angeles Department of Pediatrics, NIH Child Health Research Cancer Development Program

2013-2016              Executive Committee, American Board of Pediatrics

2013-2016              American Academy of Pediatrics-American Board of Pediatrics Executive Committee

2014-pres              External Advisory Committee, Boston Children’s Hospital, Division of Infectious Diseases, NIH T32 Training Program

2014-2015              Chair Elect, American Board of Pediatrics Board of Directors

2014-2015              Chair Elect, American Board of Pediatrics Foundation Board of Directors

2014-pres              Long-Term Investment Committee, American Board of Pediatrics

2014-2016              Nominating Committee, American Board of Pediatrics

2014-pres              External Advisory Committee, Children’s Hospital of Los Angeles, NIH Child Health Research Cancer Development Program

2015              Chair, American Board of Pediatrics Board of Directors

2015              Chair, American Board of Pediatrics Foundation Board of Directors

2015-2016              Executive Committee, Federation of Pediatric Organizations

2015-2016              Executive Oversight Committee Working Group, Pediatrics Milestones Assessment Collaboration of the National Board of Medical Examiners

2015-2019              Evaluation Committee, Pediatric Scientist Development Program

2015-pres              Chair, Research Committee, Association of Medical School Pediatric Department Chairs

2016              Past Chair, American Board of Pediatrics Board of Directors

2016              Past Chair, American Board of Pediatrics Foundation Board of Directors

2016-pres              Scientific Advisory Board, St. Jude Children’s Research Hospital

2017-2019              New Subspecialties Committee, American Board of Pediatrics

2017-pres              Credentials Committee, American Board of Pediatrics

2018              Chair, Selection Committee, Program Director of the Pediatric Scientist Development Program

2018-pres              Board of Directors, Association of Medical School Pediatric Department Chairs

2019-2021              Scientific Advisory Board, St. Jude Children’s Research Hospital (Chair)

2020-pres              Steering Committee, Association of Medical School Pediatric Department Chairs Workforce 2025 Initiative

2021-pres              Moderna External Safety Advisory Board

2021-pres              President-Elect, Association of Medical School Pediatric Department Chairs

Community

2019-pres              Board of Directors, Philadelphia Free Library

Editorial Responsibilities:

1994-2004              Associate Editor, Concise Reviews in Pediatric Infectious Diseases

1997-2007              Associate Editor, Seminars in Pediatric Infectious Diseases

2000-2006              Editorial Board, Infection and Immunity

2001-2004              Editorial Board, Pediatric Case Reviews

2002-2005              Associate Editor, The Pediatric Infectious Disease Journal

2003-2011              Editorial Advisory Board, Molecular Microbiology

2004-2019              Editorial Board, Pediatric Update CD series

2007-2018              Editorial Board, Clinical Medicine Insights: Ear, Nose and Throat

2012-2013              Associate Editor, Journal of Clinical Investigation

2013-pres              Associate Editor, Current Opinion in Pediatrics

Ad hoc reviewer

              Ad hoc reviewer: Molecular Microbiology, Infection and Immunity, Journal of Bacteriology, Journal of Clinical Microbiology, Microbiology and Molecular Biology Reviews, Cellular Microbiology, Microbial Pathogenesis, Trends in Microbiology, Microbiology, Journal of Infectious Diseases, Clinical Infectious Diseases, Pediatric Infectious Disease Journal, Vaccine, Nature Medicine, New England Journal of Medicine, Southern Medical Journal, Pediatrics, Journal of Pediatrics, Pediatric Research, Annals of Emergency Medicine, Journal of Endotoxin Research, Nature Protocols, PLoS Pathogens, PLoS One

Publications:

Original Publications, Peer-Reviewed

1.              Charron DJ, Aellen-Schulz MF, St. Geme JWIII, Erlich HA, McDevitt HO. Biochemical characterization of an invariant polypeptide associated with Ia antigens in human and mouse. Molecular Immunology 1983;20:21-30.

2.              Nataro JP, St. Geme JWIII. Septicemia due to Staphylococcus saprophyticus without associated urinary tract infection. Pediatric Infectious Disease Journal 1988;7:601-602.

3.              St. Geme JWIII, Hodes HL, Marcy SM, Pickering LK, Rodriquez WJ, McCracken GH, Jr, Nelson JD. Consensus: Management of Salmonella infection in the first year of life.  Pediatric Infectious Disease Journal 1988;7:615-621.

4.              D'Angio CT, McGowan KL, Baumgart S, St. Geme JW, Harris MC. Surface colonization with coagulase-negative staphylococci in premature neonates. Journal of Pediatrics 1989;114:1029-1034.

5.              St. Geme JWIII, Bell LM, Baumgart S, D'Angio CT, Harris MC. A method to distinguish sepsis from contamination in young infants with blood cultures growing coagulase-negative staphylococci.  Pediatrics 1990;86:157-162.

6.              St. Geme JWIII, Falkow S. Haemophilus influenzae adheres to and enters cultured human epithelial cells. Infection and Immunity 1990;58:4036-4044.

7.              St. Geme JWIII, Falkow S.  Loss of capsule expression by Haemophilus influenzae type b results in enhanced adherence to and invasion of human cells. Infection and Immunity 1991;59:1325-1333.

8.              St. Geme JWIII, Gilsdorf JR, Falkow S. Surface structures and adherence properties of diverse strains of Haemophilus influenzae biogroup aegyptius. Infection and Immunity 1991;59:3366-3371.

9.              St. Geme JWIII, Falkow S. Capsule loss by Haemophilus influenzae b results in enhanced adherence to and entry of human cells. Journal of Infectious Diseases 1992;165  (suppl):S117-S118.

10.              Rubin L, St. Geme JWIII. Role of lipooligosaccharide in virulence for infant rats of the Brazilian purpuric fever clone of Haemophilus influenzae biogroup aegyptius. Infection and Immunity 1993;61:650-655.

11.              St. Geme JWIII, Falkow S, Barenkamp SJ. High-molecular-weight proteins of nontypable Haemophilus influenzae mediate attachment to human epithelial cells. Proceedings of the National Academy of Sciences, USA 1993;90:2875-2879.

12.              St. Geme JWIII, Falkow S. Isolation, expression, and nucleotide sequencing of the pilin structural gene of the Brazilian purpuric fever clone of Haemophilus influenzae biogroup aegyptius.  Infection and Immunity 1993;61:2233-2237.

13.              St. Geme JWIII, Maldonado Y11.A, Enzmann D, Hotez PJ, Overturf GD, Schantz PM.  Consensus: Diagnosis and management of neurocysticercosis inchildren. Pediatric Infectious Disease Journal 1993;12:455-61.

14.              St. Geme JWIII, Takala A, Esko E, Falkow S. Evidence for capsule gene sequences among pharyngeal isolates of nontypable Haemophilus influenzae. Journal of Infectious Diseases 1994;169:337-342.

15.              Noel GJ, Barenkamp SJ, St. Geme JWIII, Haining WN, Mosser DM. The high-molecular weight outer membrane proteins of Haemophilus influenzae mediate binding to macrophages. Journal of Infectious Diseases 1994;169:425-429.

16.              Garver MK, St. Geme JWIII, Siegel MJ. Tularemia presenting with splenic nodules.  Pediatric Infectious Disease Journal 1994;13:830-832.

17.              Barenkamp SJ, St. Geme JWIII. Genes encoding high molecular weight adhesion proteins of nontypeable Haemophilus influenzae are part of gene clusters.  Infection and Immunity 1994;62:3320-3328.

18.              St. Geme JWIII. The HMW1 adhesin of nontypeable Haemophilus influenzae recognizes sialylated glycoprotein receptors on cultured human epithelial cells. Infection and Immunity 1994;62:3881-3889.

19.              St. Geme JWIII, de la Morena ML, Falkow S. A Haemophilus influenzae IgA protease-like protein promotes intimate interaction with human epithelial cells. Molecular Microbiology 1994;14:217-233.

20.              St. Geme JWIII, Cutter D. Evidence that surface fibrils expressed by Haemophilus influenzae type b promote attachment to human epithelial cells.  Molecular Microbiology 1995;15:77-85.

21.              Barenkamp SJ, St. Geme JWIII. Identification of a second family of high-molecular-weight adhesion proteins expressed by nontypable Haemophilus influenzae. Molecular Microbiology 1996;19:1215-1223.

22.              St. Geme JWIII, Cutter D. Influence of pili, fibrils, and capsule on in vitro adherence by Haemophilus influenzae type b.  Molecular Microbiology 1996;21:21-31.

23.              Barenkamp SJ, St. Geme JWIII. Identification of surface-exposed B-cell epitopes on high molecular weight adhesion proteins of nontypeable Haemophilus influenzae. Infection and Immunity 1996;64:3032-7.

24.              St. Geme JWIII, Pinkner JS, Krasan GP, Heuser J, Bullitt E, Smith AL, Hultgren SJ. Haemophilus influenzae pili are composite structures assembled via the HifB chaperone. Proceedings of the National Academy of Sciences, USA 1996;93:11913-11918.

25.              St. Geme JWIII, Cutter D, Barenkamp SJ.  Characterization of the genetic locus encoding Haemophilus influenzae type b surface fibrils.  Journal of Bacteriology 1996;178:6281-6287.

26.              de la Morena ML, Hendrixson D, St. Geme JWIII. Isolation and characterization of the Haemophilus influenzae uvrA gene. Gene 1996;177:23-28.

27.              Hendrixson D, de la Morena ML, Stathopoulos C, St. Geme JWIII. Structural determinants of processing and secretion of the Haemophilus influenzae Hap protein. Molecular Microbiology 1997;26:505-518.

28.              St. Geme JWIII, Kumar VV, Cutter D, Barenkamp SJ. Prevalence and distribution of the hmw and hia genes and the HMW and Hia proteins among genetically diverse strains of nontypable Haemophilus influenzae. Infection and Immunity 1998;66:364-368.

29.              St. Geme JWIII, Grass S. Secretion of the Haemophilus influenzae HMW1 and HMW2 adhesins involves a periplasmic intermediate and requires the HMWB and HMWC proteins. Molecular Microbiology 1998;27:617-630.

30.              Baorto E, Payne RM, Slater LN, Lopez F, Relman DA, Min K-W, St. Geme JWIII. Culture-negative endocarditis caused by Bartonella henselae. Journal of Pediatrics 1998;132:1051-1054.

31.              Qiu J, Hendrixson DR, Baker EN, Murphy TF, St. Geme JWIII, Plaut AG. Human milk lactoferrin inactivates two putative colonization factors expressed by Haemophilus influenzae. Proceedings of the National Academy of Sciences, USA 1998;95:12641-12646.

32.              Hendrixson DR, St. Geme JWIII. The Haemophilus influenzae Hap serine protease promotes adherence and microcolony formation, potentiated by a soluble host protein.  Molecular Cell 1998;2:841-850.

33.              Krasan GP, Cutter D, Block SL, St. Geme JWIII. Adhesin expression in matched nasopharyngeal and middle ear isolates of nontypeable Haemophilus influenzae from children with acute otitis media. Infection and Immunity 1999;67:449-454.

34.              Dawid S, Barenkamp SJ, St. Geme JWIII. Variation in expression of the Haemophilus influenzae HMW adhesins: a prokaryotic system reminiscent of eukaryotes. Proceedings of the National Academy of Sciences, USA 1999;96:1077-1082.

35.              Hunstad DA, Cohen AH, St. Geme JWIII. Successful eradication of mucormycosis occurring in a pulmonary allograft. Journal of Heart and Lung Transplant 1999;18:801-804.

36.              Krasan GP, Sauer F, Cutter D, Farley MM, Gilsdorf JR, Hultgren SJ, St. Geme JWIII.  Evidence for donor strand complementation in the biogenesis of Haemophilus influenzae hemagglutinating pili. Molecular Microbiology. 2000;35:1335-1347.

37.              Grass S, St. Geme JWIII. Maturation and secretion of the nontypable Haemophilus influenzae  HMW1 adhesin: Roles of the N-terminal and C-terminal domains. Molecular Microbiology. 2000;36:55-67.

38.              Frick AG, Joseph TD, Pang L. Rabe AM, St. Geme JWIII, Look CD. Haemophilus influenzae stimulates Intercellular Adhesion Molecule-1 (ICAM-1) expression by respiratory epithelial cells. Journal of Immunology. 2000;164:4185-4196.

39.              Clemans DL, Bauer RJ, Hanson JA, Hobbs MV, St. Geme JWIII, Marrs CF, Gilsdorf JR. Induction of proinflammatory cytokines from human respiratory epithelial cells after stimulation by nontypeable Haemophilus influenzae. Infection and Immunity. 2000;68:4430-4440.

40.              Henderson IR, Nataro JP, Kaper JB, Meyer TF, Farrand SK, Burns DL, Finlay BB, St. Geme JWIII. Renaming protein secretion in the Gram-negative bacteria. Trends in Microbiology. 2000;8:352.

41.              St. Geme JWIII, Cutter D. The Haemophilus influenzae Hia adhesin is an autotransporter protein that remains uncleaved at the C-terminus and fully cell associated. Journal of Bacteriology. 2000;182:6005-6013.

42.              Dawid S, Grass S, St. Geme JWIII. Mapping of binding domains of nontypeable Haemophilus influenzae HMW1 and HMW2 adhesins.  Infection and Immunity.  2001;69:307-314.

43.              Plaut A, Qiu J, St. Geme JWIII. Human lactoferrin proteolytic activity:  Analysis of the cleaved region in the IgA  protease of Haemophilus  influenzae.   Vaccine.  2001;19:S148-S152.

44.              Ogilvie C, Omikunle A, Wang Y, St. Geme JWIII, Rodriguez CA, Adderson EE  A Capsulation loci of non-serotype b encapsulated Haemophilus influenzae. Journal of Infectious Diseases. 2001:184:144-149.

45.              Fink DL, Cope LD, Hansen EJ, St. Geme JWIII. The Haemophilus influenzae Hap autotransporter is a chymotrypsin clan serine protease and undergoes autoproteolysis via an intermolecular mechanism. Journal of Biological Chemistry. 2001;276:39492-39500.

46.              Omikunle A, Takahashi S, Oglivie CL, Wang Y, Rodriguez CA, St. Geme JWIII, Adderson EE. Limited genetic diversity of recent invasive isolates of non-serotype b encapsulated Haemophilus influenzae. Journal of Clinical Microbiology. 2002;40:1264-1270.

47.              Pearson MP, Lafontaine ER, Wagner NJ, St. Geme JWIII, Hansen EJ. A hag mutant of Moraxella catarrhalis strain O35E is deficient in hemagglutination, autoagglutination, and IgD-binding activities. Infection and Immunity. 2002;70:4523-4533.

48.              Cutter D, Mason KW, Mountzouros K, Fink DL, Green BA, St. Geme JWIII. Immunization with the Haemophilus influenzae Hap adhesin protects against nasopharyngeal colonization in experimental mice. Journal of Infectious Diseases. 2002;186:1115-1121.

49.              Fink DL, Green BA, St. Geme JWIII. The Haemophilus influenzae Hap autotransporter binds to fibronectin, laminin, and collagen IV. Infection and Immunity. 2002;70:4902-4907.

50.              Laarmann S, Cutter D, Juehne T, Barenkamp SJ, St. Geme JWIII. The Haemophilus influenzae Hia autotransporter harbors two adhesive pockets that reside in the passenger domain and recognize the same host cell receptor. Molecular Microbiology. 2002;46:731-743.

51.              Hendrixson DR, Qiu J, Shewry SC, Fink DL, Petty S, Baker EN, Plaut AG, St. Geme JWIII. Human milk lactoferrin is a serine protease that cleaves Haemophilus surface proteins at arginine-rich sites. Molecular Microbiology. 2003;47:607-617.

52.              Fink DL, Buscher AZ, Green BA, Fernsten P, St. Geme JWIII. The Haemophilus influenzae Hap autotransporter mediates microcolony formation and adherence to epithelial cells and extracellular matrix via binding regions in the C-terminal end of the passenger domain. Cellular Microbiology. 2003;5:175-186.

53.              Fink DL, St. Geme JWIII. Chromosomal expression of the Haemophilus influenzae Hap autotransporter allows fine-tuned regulation of adhesive potential via inhibition of intermolecular proteolysis. Journal of Bacteriology. 2003;185:1608-1615.

54.              Grass S, Buscher AZ, Swords WE, Apicella MA, Barenkamp SJ, Ozchlewski N, St. Geme JWIII. The Haemophilus influenzae HMW1 adhesin is glycosylated in a process that requires the HMW1C protein and an enzyme important for lipooligosaccharide biosynthesis. Molecular Microbiology. 2003;48:737-751.

55.              Rodriguez CA, Buscher AZ, Smith AL, St. Geme JWIII, Adderson EE. Prevalence and distribution of adhesin genes in invasive non-type b encapsulated Haemophilus influenzae. Infection and Immunity. 2003;71:1635-1642.

56.              O’Neill JM, St. Geme JWIII, Cutter D, Adderson EE, Anyanwu J, Jacobs RF, Schutze GE. Invasive disease due to nontypable Haemophilus influenzae among children in Arkansas. Journal of Clinical Microbiology. 2003; 41:3064-3069.

57.              Garbutt J, May A, St. Geme JWIII, Shackelford PG. Developing community-specific recommendations for first-line treatment of acute otitis media:  Is high-dose amoxicillin necessary?  Pediatrics. 2004; 114:342-347.

58.              Surana NK, Cutter D, Barenkamp SJ, St. Geme JWIII. The Haemophilus influenzae Hia autotransporter contains an unusually short, trimeric translocator domain. Journal of Biological Chemistry. 2004;279:14679-14685.

59.              Yeo H-J, Cotter SE, Laarmann S, Juehne T, St. Geme JWIII, Waksman G.  Structural basis for host recognition by the Haemophilus influenzae Hia autotransporter.  EMBO Journal. 2004;23:1245-1256.

60.              Buscher AZ, Burmeister K, Barenkamp SJ, St. Geme JWIII.  Evolutionary and functional relationships among the nontypeable Haemophilus influenzae HMW family of adhesins.  Journal of Bacteriology. 2004;186:4209-4217.

61.              Surana NK, Grass S, Hardy GG, Li H, Thanassi DG, St. Geme JWIII. Evidence for conserved architecture and physical properties of Omp85-like proteins throughout evolution. Proceedings of the National Academy of Sciences USA. 2004;101:14497-14502.

62. Liu D-F, Mason KW, Mastri M, Pazirandeh M, Cutter D, Fink DL, St. Geme JWIII, Zhu D, Green BA. A C-terminal fragment of the internal 110-kilodalton passenger domain of the Hap protein of nontypeable Haemophilus influenzae is a potential vaccine candidate. Infection and Immunity. 2004;72:6961-6968.
63. Surana NK, St. Geme JWIII. Lymphangitis after self-administration of lipopolysaccharide: Implications for mechanisms of disease. New England Journal of Medicine. 2005;352:944-945.
64. Cotter SE, Surana NK, St. Geme JWIII. Trimeric autotransporters: A distinct subfamily of autotransporter proteins. Trends in Microbiology. 2005;13:199-205.
65. Cotter SE, Yeo H-J, Juehne T, St. Geme JWIII. Architecture and adhesive activity of the Haemophilus influenzae Hsf adhesin. Journal of Bacteriology. 2005;187:4656-4664.
66. Sukupolvi-Petty S, Grass S, St. Geme JWIII.  The Haemophilus influenzae type b hcsA and hcsB gene products facilitate transport of capsular polysaccharide across the outer membrane and are essential for virulence. Journal of Bacteriology. 2006;188:3870-3877.
67. Webster P, Wu S, Gomez G, Apicella M, Plaut AG, St. Geme JWIII. Distribution of bacterial proteins in biofilms formed by non-typeable Haemophilus influenzae.  Journal of Histochemistry and Cytochemistry. 2006;54:829-842.
68. Buscher AZ, Grass S, Heuser J, Roth R, St. Geme JWIII. Surface anchoring of a bacterial adhesin secreted by the two-partner secretion system. Molecular Microbiology. 2006;61:470-483.
69. Meng G, Surana NK, St. Geme JWIII, Waksman G. Structure of the outer membrane translocator domain of the Haemophilus influenzae Hia trimeric autotransporter. EMBO Journal. 2006;25:2297-2304.
70. Cotter SE, Surana NK, Grass S, St. Geme JWIII. Trimeric autotransporters require trimerization of the passenger domain for stability and adhesive activity. Journal of Bacteriology.  2006;188:5400-5407.
71. Surana NK, Buscher AZ, Hardy GG, Kehl-Fie T, Grass S, St. Geme JWIII. Translocator proteins in the two-partner secretion family have multiple domains. Journal of Biological Chemistry. 2006;281:18051-18058.
72. Kehl-Fie T, St. Geme JWIII. Identification and characterization of an RTX toxin in the emerging pathogen Kingella kingae. Journal of Bacteriology. 2007;189:430-436.
73. Li H, Grass S, Wang T, Liu T, St. Geme JWIII. Structure of the Haemophilus influenzae HMW1B translocator protein: Evidence for a twin-pore. Journal of Bacteriology. 2007;189:7497-7502.
74. Yeo H-J, Yokoyama T, Walkiewicz K, Kim Y, Grass S, St. Geme JWIII. The structure of the Haemophilus influenzae HMW1 pro-piece reveals a structural domain that is essential for bacterial two-partner secretion. Journal of Biological Chemistry. 2007;42:31076-31084.
75. Sheets AJ, Grass S, Miller S, St. Geme JWIII.  Identification of a novel trimeric autotransporter adhesin in the cryptic genospecies of Haemophilus. Journal of Bacteriology. 2008;190:4313.
76. Cholon D, Cutter D, Richardson SK, Sethi S, Murphy TF, Look DC, St. Geme JWIII. Serial isolates of Haemophilus influenzae from patients with chronic obstructive pulmonary disease express diminishing quantities of the HMW1 and HWM2 adhesins. Infection and Immunity. 2008;76:4463-4468.
77. Gross J, Grass S, Davis AE, Gilmore-P, Townsend RR, St. Geme JWIII. The Haemophilus influenzae HMW1 adhesin is a glycoprotein with an unusual N-linked carbohydrate modification. Journal of Biological Chemistry, 2008;283:26010-26015.
78. Kehl-Fie TE, Miller SE, St. Geme JWIII. Kingella kingae expresses type IV pili that mediate adherence to respiratory epithelial and synovial cells. Journal of Bacteriology. 2008;190:7157-7163.
79. Meng G, St. Geme JWIII, Waksman G. Crystal structures of Hia fragments reveal a repetitive architecture in the Haemophilus influenzae Hia trimeric autotransporter. Journal of Molecular Biology. 2008; 384:824-36
80. Kenjale R, Meng G, Fink DL, Juehne T, Ohashi T, Erickson HP, Waksman G, St Geme JWIII: Structural determinants of autoproteolysis of the Haemophilus influenzae Hap autotransporter. Infect Immun. 2009;77: 4704-4713.
81. Kehl-Fie TE, Porsch EA, Miller SE, St. Geme JWIII. Expression of Kingella kingae type IV pili is regulated by 54, PilS, and PilR. Journal of Bacteriology 2009;191:4976-4986.
82. Radin JN, Grass S, Meng G, Cotter SE, Waksman G, St. Geme JWIII. Structural basis for the differential binding affinities of the HsfBD1 and HsfBD2 domains in the Haemophilus influenzae Hsf adhesin. Journal of Bacteriology 2009;191:5068-5075.
83. Kehl-Fie TE, Porsch EA, Yagupsky P, Grass EA, Olbert C, Benjamin DK, Jr., St. Geme JWIII. Examination of type IV pilus expression and pilus-associated phenotypes in Kingella kingae clinical isolates. Infection and Immunity. 2010;78:1692-1699.
84. Grass S, Lichti C, Townsend RR, Gross J, St. Geme JWIII. The Haemophilus HMW1C protein is a glycosyltransferase that transfers hexose residues to asparagine sites in the HMW1 adhesin. PLoS Pathogens.  2010;6:e1000919.
85. Choi K-J, Grass S, Paek S, St. Geme JWIII, Yeo H-J. The Actinobacillus pleuropneumoniae HMW1C-like protein mediates N-linked glycosylation of the Haemophilus influenzae HMW1 adhesin. PLoS One, 2010;5:e15888.
86. Sheets AJ, St. Geme JWIII. Adhesive activity of the Haemophilus cryptic genospecies Cha autotransporter is modulated by a novel mechanism involving variation in peptide repeats. Journal of Bacteriology. 2011;193:329-339.
87. Meng G, Spahich N, Kenjale R, Waksman G, St. Geme JWIII. Crystal structure of the Haemophilus influenzae Hap adhesin reveals an intercellular oligomerization mechanism for bacterial aggregation. EMBO Journal, 2011;30:3864-3874.
88. Kawai F, Grass S, Kim Y, Choi K-J, St. Geme JWIII, Yeo H-J. Structural insights into the glycosyltransferase activity of the Actinobacillus pleuropneumoniae HMW1C-like protein. Journal of Biological Chemistry, 2011;286:38546-38557.
89. Spahich NA, Hood DW, Moxon ER, St. Geme JWIII. Inactivation of Haemophilus influenzae LPS biosynthesis genes interferes with outer membrane localization of the Hap autotransporter. Journal of Bacteriology, 2012;194:1815-1822.
90. Porsch EA, Kehl-Fie TE, St. Geme JWIII. Modulation of Kingella kingae adherence to human epithelial cells by type IV pili, capsule, and a novel trimeric autotransporter. mBio, 2012;3(5):00372.
91. Porsch EA, Johnson MDL, Broadnax AD, Garrett CG, Redinbo MR, St. Geme JWIII. Differential control of Kingella kingae type IV pilus phenotypes through the calcium-binding sites of PilC1 and PilC2. Journal of Bacteriology, 2013;195:886-895.
92. Starr KF, Porsch EA, Heiss C, Black I, Wang Z, Azadi P, St. Geme JWIII. Characterization of the Kingella kingae polysaccharide capsule and exopolysaccharide. PLoS One, 2013; DOI: 10.1371/journal.pone.0075409.
93. McCann JR, Sheets AJ, Grass S, St. Geme JWIII. The Haemophilus cryptic genospecies Cha adhesin has at least two variants that differ in host cell binding, bacterial aggregation, and biofilm formation properties. Journal of Bacteriology, 2014;196:1780-1788.
94. Spahich NA, Kenjale R, McCann JR, Meng G, Ohashi T, Erickson H, St. Geme JWIII. Determinants of interactions between the Haemophilus influenzae Hap autotransporter and fibronectin. Microbiology. 2014;160:1182-1190.
95. Arnold CJ, Garrigues G, St. Geme JWIII, Sexton D. Necrotizing fasciitis by Haemophilus influenzae type f: A case report and review of the literature. Journal of Clinical Microbiology. 2014;52:3471-3474.
96. Lautz AJ, Jenssen B, McGuire J, St. Geme JWIII. A 33-month-old with fever and altered mental status. Pediatrics. 2015;135:120-125.
97. Mendoza FS, Walker LR, Stoll BJ, Fuentes-Afflick E, St. Geme JWIII, Cheng TL, Gonzalez del Rey JA, Harris CE, Rimsza ME, Li J, Sectish TC. Diversity and Inclusion Training in Pediatric Departments. Pediatrics. 2015;135:doi/10.1542/peds.2014-1653.
98. Lei J, Cai X, Ma X, Zhang L, Li Y, Dong X, St. Geme JWIII, Meng G. Recombinant expression, purification, crystallization, and preliminary X-ray diffraction analysis of Haemophilus influenzae BamD and BamCD complex. Acta Crystallography. 2015;F71:234-238.
99. Grass S, Rempe KA, St. Geme JWIII. Structural determinants of the interaction between the TpsA and TpsB proteins in the Haemophilus influenzae HMW1 two-partner secretion system. Journal of Bacteriology. 2015:197:1769-1780.
100. Syed S, Tran D, Kemper A, St. Geme JWIII, Lantos J. Ethics Rounds: Authorship concerns and who truly owns a research idea? Pediatrics. 2015;136:969-973.
101. Rempe KA, Spruce LA, Porsch EA, Seeholzer SH, Nørskov-Lauritsen N, St. Geme JWIII. Unconventional N-linked glycosylation promotes trimeric autotransporter function in Kingella kingae and Aggregatibacter aphrophilus. mBio. 2015;6(4):1206-1215.
102. Mell JC, Viadas C, Sinha S, Moleres J, Porsch EA, St. Geme JWIII, Nislow C, Redfield RJ, Garmendia J. Transformed recombinant enrichment profiling rapidly identifies HMW1 as an intracellular invasion locus in Haemophilus influenzae. PLoS Pathogens. 2016; 12(4): e1005576. doi:10.1371/journal.ppat.1005576
103. McCann JR, Mason SN, Auten RW, St. Geme JWIII, Seed PC. Early life intranasal colonization with nontypeable Haemophilus influenzae exacerbates juvenile airways disease in mice. Infection and Immunity. 2016;84:2022-2030.
104. Starr KF, Porsch EA, Seed PC, and St. Geme JWIII. Genetic and molecular basis of Kingella kingae encapsulation. Infection and Immunity. 2016;84:1775-1784.
105. Rempe KA, Porsch EA, Wilson J, St. Geme JWIII.  The Haemophilus influenzae HMW1 and HMW2 adhesins promote upper respiratory tract colonization in rhesus macaque monkeys. Infection and Immunity. 2016;84:2771-2778.
106. Starr F, Porsch EA, Seed PC, Heiss C, Naran R, Forsberg LS, Amit U, Yagupsky P, Azadi P, St. Geme JWIII. Kingella kingae expresses four structurally distinct polysaccharide capsules that differ in their correlation with invasive disease. PLoS Pathogens. 2016;12(10): e1005944.
107. First LR, Gremse DA, St. Geme JWIII. Maintenance of Certification: A Prescription for Improved Child Health. JAMA Pediatrics. 2017 Feb 27. doi: 10.1001/jamapediatrics.2016.4686.
108. Porsch EA, Starr K, Yagupsky P, St. Geme JWIII. The type a and type b polysaccharides capsules predominate in an international collection of invasive Kingella kingae isolates. mSphere. 2017;2(2):e00060-17.
109. Barrett DJ, McGuinness GA, Cunha CA, Emans SJ, Gershon WT, Hazinski MF, Lister G, Murray KF, St. Geme JWIII, Whitley-Williams PN. Pediatric Hospital Medicine – A proposed new subspecialty. Pediatrics. 2017 Mar;139(3). pii: e20161823. doi: 10.1542/peds.2016-1823.
110. Shaw KN, Tanzer L, Keren R, Taylor A, DeRusso T, St. Geme JWIII. Part 4 Maintenance of Certification: From Trial to Tribute. Journal of Pediatrics. 2017 Jun;185:4-5.e1. doi: 10.1016/j.jpeds.2017.03.016. Epub 2017 Mar 28.
111. Kern B, Porsch EA, St. Geme JWIII. Defining the mechanical determinants of Kingella kingae adherence to host cells. Journal of Bacteriology. 2017; 199:e00314-17.
112. Muñoz VL, Porsch EA, St. Geme JWIII. Kingella kingae surface polysaccharides promote resistance to human serum and virulence in a juvenile rat model. Infection and Immunity. 2018 May 22;86(6). pii: e00100-18. doi: 10.1128/IAI.00100-18.
113. Spyridakis E, Gerber JS, Schriver E, Anatale-Tardiff L, Grundmeier RW, Porsch EA, St. Geme JWIII, Downes KJ. Clinical features and outcomes of children with culture-negative septic arthritis. Journal of the Pediatric Infectious Disease Society. 2018 April 30. https://doi.org/10.1093/jpids/ piy034.
114. Kalograiaki I, Euba B, del Carmen Fernandez-Alonso M, Proverbio D, St. Geme JWIII, Aastrup T, Garmendia J, Canada FJ, Solis D. Differential recognition of Haemophilus influenzae whole bacterial cells and isolated lipooligosaccharides by galactose-specific lectins. Scientific Reports. 2018; 8:16292 | DOI:10.1038/s41598-018-34383.
115. Muñoz VL, Porsch EA, St. Geme JWIII. Kingella kingae surface polysaccharides promote resistance to neutrophil phagocytosis and killing. mBio. 2019 June 25;10(3). Pii: e00631-19. doi: 10.1128.
116. DeRusso P, Greeley WJ, St. Geme JWIII. Leading from the middle: benefits of a physician leadership program. Journal of Pediatrics. 2020 April;219:4-6.e1. doi: 10.1016.
117. Porsch EA, Yagupsky P, St. Geme JWIII. Kingella negevensis shares multiple putative virulence factors with Kingella kingae. PLoS ONE. October 30; 2020. https://doi.org/10.1371/journal.pone.0241511
118. Spahich NA, St. Geme JWIII. Insights into outer membrane insertion of the Haemophilus influenzae Hia autotransporter via the Bam complex. In Review.
119. Kadry N, Porsch EA, Shen H, St. Geme JWIII. Immunization with the HMW1 and HMW2 adhesins protects against nasopharyngeal colonization by heterologous strains of nontypeable Haemophilus influenzae. Proceedings of the National Academy of Sciences, USA. August 10, 2021. https://doi.org/10.1073/pnas.2019923118
120. Sacharok AL, Porsch EA, Yount TA, Keenan O, St. Geme JWIII. Kingella kingae PilC1 and PilC2 are adhesive multifunctional proteins that promote bacterial adherence, twitching motility, DNA transformation, and pilus biogenesis. PLoS Pathogens. 2022. https://doi.org/10.1371/journal.ppat.1010440
121. Sacharok AL, Porsch EA, St. Geme JWIII. The Kingella kingae PilC1 MIDAS motif is essential for type IV pilus adhesive activity. mBio. In Revision.
122. Montoya NR, Porsch EA, Muñoz VL, Muszyński A, Vlach J, Hahn DK, Azadi P, Sherman M, Yang H, Chandler CE, Ernst RK, St. Geme JWIII. Surface anchoring of the Kingella kingae galactan is dependent on the lipopolysaccharide O-antigen. In Review.

Invited Publications, Peer-Reviewed:

1.              St. Geme JWIII, Polin RA. Neonatal sepsis: progress in diagnosis and management. Drugs 1988;36:784-800.

2.              St. Geme JWIII, Harris MC.  Neonatal coagulase-negative staphylococcal disease. Clinics in Perinatology 1991;18:281-302.

3.              St. Geme JWIII. Nontypable Haemophilus influenzae disease: epidemiology, pathogenesis, and prospects for prevention. Infectious Agents and Disease 1993;2:1-16.

4.              Hultgren SJ, Abraham S, Caparon M, Falk P, St. Geme JWIII, Normark S. Pilus and nonpilus bacterial adhesins: assembly and function in cell recognition. Cell 1993;73:887-901.

5.              St. Geme JWIII. Progress toward development of a vaccine for nontypable Haemophilus influenzae. Annals of Medicine. 1996;28:31-37.

6.              St. Geme JWIII. Molecular determinants of the interaction between Haemophilus influenzae and human cells. American Journal of Respiratory and Critical Care Medicine. 1996;154:S192-S196.

7.              Krasan GP, St. Geme JWIII. Invasive disease due to nontypable Haemophilus influenzae.  The Report on Pediatric Infectious Diseases 1997;7:11-12.

8.              St. Geme JWIII. Insights into the mechanism of respiratory tract colonization by nontypable Haemophilus influenzae. The Pediatric Infectious Disease Journal 1997;16:931- 935.

9.              Rao R, Krasan GP, Hendrixson DR, Dawid S, St. Geme JWIII. Molecular determinants of the pathogenesis of disease due to nontypable Haemophilus influenzae.  FEMS Microbiology Reviews 1999;23:99-129.

10.              Bennett J, St. Geme JWIII. Bacterial resistance and antibiotic use in the emergency department. Pediatric Clinics of North America. 1999;46:1125-1143.

11.              Stathopoulos C, Hendrixson D, Thanassi D, Hultgren SJ, St. Geme JWIII, Curtiss RIII.  Secretion of virulence determinants by the general secretory pathway in Gram-negative pathogens: An evolving story. Microbes and Infection. 2000;2:1061-1072.

12.              Hunstad DA, St. Geme JWIII. Staphylococcus aureus with reduced susceptibility to glycopeptide antibiotics. Pediatric Infectious Disease Journal. 2000;19:1093-1096.

13.              St. Geme JWIII. The pathogenesis of nontypable Haemophilus influenzae otitis media.  Vaccine. 2001;19:S41-S50.

14.              St. Geme JWIII. Molecular and cellular determinants of nontypable Haemophilus influenzae adherence and invasion. Cellular Microbiology. 2002; 4:191-200.

15. St. Geme JWIII. Molecular determinants of Haemophilus influenzae colonization. Proceedings of the Seventh International Symposium on Recent Advances in Otitis Media with Effusion, on CD ROM, BC Decker Inc., Hamilton, Canada, 2002.
16. Barenkamp SJ, Ogra PL, Bakaletz LO, Chonmaitree T, Heikkinen T, Hurst DS, Kawauchi H, Kurono Y, Leiberman A, Murphy TF, Patel JA, Sih TM, St. Geme JWIII, Stenfors L-E.  Report of the Eighth Research Conference on Recent Advances in Otitis Media:  Microbiology and Immunology. Annals of Otology, Rhinology, and Laryngology, 2005 (Supplement 194);114:60-85.
17. St. Geme JWIII, Yeo H-J. A prototype two-partner secretion pathway: the Haemophilus influenzae HMW1 and HMW2 adhesin systems. Trends in Microbiology. 2009;17:355-360.
18. Yagupsky P, Porsch E, St. Geme JWIII. Kingella kingae: An emerging pathogen in young children. Pediatrics. 2011;127:557-565.
19. Spahich NA, St. Geme JWIII. Structure and function of the Haemophilus influenzae autotransporters. Frontiers in Cellular and Infection Microbiology. 2011;1:1-5.
20. Stapleton FB, McColley S, St. Geme JWIII. Scholarship during fellowship: Flexibility unrealized. Pediatrics. 2014; 133 (Supplement):S80-S81.
21. McCann J, St. Geme JWIII. The HMW1C-like glycosyltransferases - an enzyme family with a sweet tooth for simple sugars. PLoS Pathogens. 2014;10(4): e1003977. doi:10.1371/ journal. ppat.1003977
22. Jaramillo D, Dormans J, Delgado J, Laor T, St. Geme JWIII. Hematogenous osteomyelitis in infants and children: imaging of a changing disease. Radiology. 2017;283:629-643.
23. Dermody TS, Hirsch R, Hostetter MK, Orange JS, St. Geme JWIII. Expanding the pipeline for pediatric physician-scientists. Journal of Pediatrics. 2019;207:3–7.e1.
24. Muñoz VL, Porsch EA, St. Geme JWIII. Virulence determinants of the emerging pathogen Kingella kingae. Current Opinions in Microbiology. 2020;54:37-42. https://doi.org/10.1016/ j.mib.2020.01.009.
25. St. Geme, JWIII. The 2020 Joseph W. St. Geme, Jr. Leadership Award Address: On Leadership and the Joy of Pediatrics. Pediatrics. 2021. Dec 1;148(6):e2021053872.doi: 10.1542/peds.2021-053872.
26. Davis SD, Fineman JR, St. Geme JWIII. Insights into the impact of sections and departments on your career. Pediatric Research. 2021. Nov 25;1-9.doi: 10.1038/s41390-021-01825-8. 
27. Porsch EA, Hernandez K, Montoya N, Morreale D, Yount T, St. Geme JWIII. Determinants of Kingella kingae pathogenicity as a major cause of osteoarticular infections. Frontiers of Pediatrics.

Book Chapters:

1. St. Geme JWIII, Polin RA. Neonatal Septicemia, Meningitis, and Pneumonia. In Current Pediatric Therapy, Vol 14 (eds. Gellis SS and Kagan BM), WB Saunders, 1990.
2. St. Geme JWIII. Bacterial Meningitis. In Pediatric Primary Care: a Problem-Oriented Approach, Second Edition (eds. Schwartz MW, Charney EB, Curry TA, and Ludwig S).  Year Book Medical Publishers, 1990.
3. Polin RA, St. Geme JWIII. Neonatal Sepsis. In Advances in Pediatric Infectious Diseases, Vol. 7 (ed. Aronoff S). Year Book Medical Publishers, 1992; pp. 25-61.
4. St. Geme JWIII. Early Events in the Pathogenesis of Haemophilus influenzae Disease. In Molecular Genetics of Bacterial Pathogenicity. (eds. Miller V, Kaper J, Portnoy D, Isberg R).  American Society for Microbiology, Washington, DC, 1994; pp. 157-172.
5. St. Geme JWIII, Polin RA. Prevention and Treatment of Neonatal Sepsis. In Intensive Care of the Fetus and Newborn (ed. Spitzer A). Mosby, Inc., St. Louis, 1995; pp. 927-939.
6. St. Geme JWIII, Haslam DB, Ditmar MF. Infectious Diseases. In Pediatric Secrets, Second Edition.  (eds. Polin RA, Ditmar MF). Hanley & Belfus, Inc., Philadelphia, 1996; pp. 255-308.
7. St. Geme JWIII. Haemophilus Influenzae. In Principles and Practice of Pediatric Infectious Diseases (eds. Long SS, Pickering LK, Prober CG). Churchill Livingstone, New York, 1996; pp. 1019-1027.
8. St. Geme JWIII. Other Haemophilus Species. In Principles and Practice of Pediatric Infectious Diseases (eds. Long SS, Pickering LK, Prober CG). Churchill Livingstone, New York, 1996; pp. 1027-1029.
9. St. Geme JWIII. Staphylococcus Epidermidis and Other Coagulase-Negative Staphylococci. In Principles and Practice of Pediatric Infectious Diseases (eds. Long SS, Pickering LK, Prober CG). Churchill Livingstone, New York, 1996; pp. 793-801.
10. St. Geme JWIII. Classification of Bacteria. In Principles and Practice of Pediatric Infectious Diseases (eds. Long SS, Pickering LK, Prober CG). Churchill Livingstone, New York, 1996; pp. 778-780.
11. Haslam DB, St. Geme JWIII. Classification of Streptococci. In Principles and Practice of Pediatric Infectious Diseases (eds. Long SS, Pickering LK, Prober CG). Churchill Livingstone, New York, 1996; pp. 801-802.
12. Haslam DB, St. Geme JWIII. Enterococci. In Principles and Practice of Pediatric Infectious Diseases (eds. Long SS, Pickering LK, Prober CG). Churchill Livingstone, New York, 1996; pp 818-821.
13. Haslam DB, St. Geme JWIII. Viridans Streptococci, Nutritionally Variant Streptococci, and Streptococcus bovis. In Principles and Practice of Pediatric Infectious Diseases (eds. Long SS, Pickering LK, Prober CG). Churchill Livingstone, New York, 1996; pp. 821-826.
14. Haslam DB, St. Geme JWIII. Groups C and G Streptococci. In Principles and Practice of Pediatric Infectious Diseases (eds. Long SS, Pickering LK, Prober CG). Churchill Livingstone, New York, 1996; pp. 826-828.
15. Haslam DB, St. Geme JWIII. Other Gram-Positive, Catalase-Negative Cocci: Leuconostocs and Pediococci. In Principles and Practice of Pediatric Infectious Diseases (eds. Long SS, Pickering LK, Prober CG). Churchill Livingstone, New York, 1996; pp. 835-837.
16. St. Geme JWIII. Bacterial Adhesins: Determinants of Microbial Colonization and Pathogenicity. In Advances in Pediatrics, Vol. 4 (ed. Barness LA), Mosby-Yearbook, Inc., Chicago. 1997; pp. 662-669.
17. St. Geme JWIII. Bacterial Meningitis. In Pediatric Primary Care: a Problem-Oriented Approach, Third Edition (eds. Schwartz MW, Curry TA, Sargent AJ, Blum NJ, and Fein J).  Year Book Medical Publishers, Chicago. 1997; pp. 662-669.
18. Shinefield HR, St. Geme JWIII. Staphylococcal Infections. In Infections of the Fetus and Newborn, Fifth Edition, (eds. Remington JS, Klein JD), WB Saunders, Philadelphia. 2000; pp. 1217-1247.
19. St. Geme JWIII. Haemophilus, Bordetella, and Branhamella. In Current Treatment in Infectious Disease (eds. Wilson W, Sande M, Drew L, Henry N, Relman D, Steckelberg J and Gerberding J), Appleton and Lange, Stamford, CT. 2001; pp. 587-602.
20. Elward AM, Hunstad DA, St. Geme JWIII. Infectious Diseases. In Pediatric Secrets, Third Edition.  (eds. Polin RA, Ditmar MF). Hanley & Belfus, Inc., Philadelphia. 2001; pp. 319-387.
21. Fink D, St. Geme JWIII.  The Genus Haemophilus.  In The Prokaryotes.  (eds. Dworkin M, Falkow S, Rosenberg E, Schliefer K-H, Stackenbrandt E).  Springer-Verlag, Inc. New York. Harcourt, Inc., Orlando, 2001; Release 3.5 (3/13/01).
22. Krasan GP, St. Geme JWIII. Haemophilus. In McGraw-Hill Encyclopedia of Science and Technology, Ninth Edition. McGraw-Hill, New York. 2002; Volume 8.
23. Hardy GG, Tudor SM, St. Geme JWIII. The Pathogenesis of Nontypable Haemophilus influenzae Disease. In Methods in Molecular Medicine (Ed. Herbert M). The Humana Press Inc., Totowa, NJ. 2002; pp. 71:1-28.
24. St. Geme JWIII. Haemophilus influenzae. In Principles and Practice of Pediatric Infectious Diseases, Second Edition. (eds. Long SS, Pickering LK, Prober CG). Harcourt, Inc., Orlando, 2003; pp. 919-925.
25. St. Geme JWIII. Other Haemophilus Species. In Principles and Practice of Pediatric Infectious Diseases, Second Edition. (eds. Long SS, Pickering LK, Prober CG). Harcourt, Inc., Orlando, 2003; pp. 925-928.
26. St. Geme JWIII. Staphylococcus Epidermidis and Other Coagulase-Negative Staphylococci. In Principles and Practice of Pediatric Infectious Diseases, Second Edition. (eds. Long SS, Pickering LK, Prober CG). Harcourt, Inc., Orlando, 2003; pp. 707-714.
27. St. Geme JWIII. Classification of Bacteria. In Principles and Practice of Pediatric Infectious Diseases, Second Edition. (eds Long SS, Pickering LK, Prober CG). Harcourt, Inc., Orlando, 2003; pp. 692-694.
28. Haslam DB, St. Geme JWIII. Classification of Streptococci. In Principles and Practice of Pediatric Infectious Diseases, Second Edition. (eds. Long SS, Pickering LK, Prober CG). Harcourt, Inc., Orlando, 2003; pp. 714-715.
29. Haslam DB, St. Geme JWIII. Enterococcus Species. In Principles and Practice of Pediatric Infectious Diseases, Second Edition. (eds. Long SS, Pickering LK, Prober CG). Harcourt, Inc., Orlando, 2003; pp.731-734.
30. Haslam DB, St. Geme JWIII. Viridans Streptococci, Streptococcus bovis, and Abiotrophia Species. In Principles and Practice of Pediatric Infectious Diseases, Second Edition. (eds. Long SS, Pickering LK, Prober CG). Harcourt, Inc., Orlando, 2003; pp. 734-737.
31. Haslam DB, St. Geme JWIII. Groups C and G Streptococci. In Principles and Practice of Pediatric Infectious Diseases, Second Edition. (eds. Long SS, Pickering LK, Prober CG). Harcourt, Inc., Orlando, 2003; pp. 738-739.
32. Haslam DB, St. Geme JWIII. Other Gram-Positive, Catalase-Negative Cocci: Leuconostocs and Pediococci. In Principles and Practice of Pediatric Infectious Diseases, Second Edition. (eds. Long SS, Pickering LK, Prober CG). Harcourt, Inc., Orlando, 2003; pp. 747-748.
33. Hunstad DA, St. Geme JWIII. Molecular Determinants of Microbial Pathogenesis. In Textbook of Pediatric Infectious Diseases, Fifth Edition (eds. Feigin RD, Cherry JD, Kaplan S, Demmler G). WB Saunders, Philadelphia, 2003; pp. 2-20.
34. St. Geme, JWIII. Haemophilus influenzae Infections. In Red Book, 26th Edition (eds. American Academy of Pediatrics Committee on Infectious Diseases). American Academy of Pediatrics, Elk Grove Village, IL, 2003; pp. 293-301.
35. St. Geme JWIII. Non-Group A or B Streptococcal and Enterococcal Infections. In Red Book, 26th Edition (eds. American Academy of Pediatrics Committee on Infectious Diseases). American Academy of Pediatrics, Elk Grove Village, IL, 2003; pp. 591-595.
36. Fink DL, St. Geme JWIII. Hap Gene Product of Haemophilus influenzae. In Handbook of Proteolytic Enzymes, Second Edition. (eds. Barrett AJ, Rawlings ND, Woessner, JF). Elsevier Academic Press, London. 2004; pp. 1765-1767.
37. Surana NK, Cotter SE, Yeo H-J, Waksman G, St. Geme JWIII.  Structural Determinants of Haemophilus influenzae Adherence to Host Epithelium:  Variations on Type V Secretion.  In Structural Basis of Bacterial Pathogenesis (eds. Waksman G, Caparon MG, Hultgren SJ). American Society for Microbiology, Washington, DC.  2005; pp. 129-148.
38. Elward AM, Hunstad DA, St. Geme JWIII. Infectious Diseases. In Pediatric Secrets, Fourth Edition.  (eds. Polin RA, Ditmar MF). Elsevier Mosby, Philadelphia. 2005; pp. 310-369.
39. Orscheln RC, Shinefield HR, St. Geme JWIII. Staphylococcal Infections. In Infections of the Fetus and Newborn, Sixth Edition, (eds. Remington JS, Klein JD, Wilson CB, Baker CB), WB Saunders, Philadelphia. 2006; pp. 513-543.
40. St. Geme, JWIII. Haemophilus influenzae Infections. In Red Book, 27th Edition (eds. American Academy of Pediatrics Committee on Infectious Diseases). American Academy of Pediatrics, Elk Grove Village, IL, 2006; pp. 310-318.
41. St. Geme JWIII. Joseph W. St. Geme, Jr., M.D.: Optimist, Scholar, Visionary, and Role Model (April 10, 1931-October 11, 1986). In Advances in Pediatrics, Mosby-Yearbook, Inc., Chicago, IL, 2007, Volume 54, pp. 3-8.
42. St. Geme JWIII. Haemophilus influenzae. In Principles and Practice of Pediatric Infectious Diseases, Third Edition. (eds. Long SS, Pickering LK, Prober CG). Harcourt, Inc., Orlando, 2008, pp. 892-898.
43. St. Geme JWIII. Classification of Bacteria. In Principles and Practice of Pediatric Infectious Diseases, Third Edition. (eds. Long SS, Pickering LK, Prober CG). Harcourt, Inc., Orlando, 2008; pp. 677-679.
44. Haslam DB, St. Geme JWIII. Classification of Streptococci. In Principles and Practice of Pediatric Infectious Diseases, Third Edition. (eds. Long SS, Pickering LK, Prober CG). Harcourt, Inc., Orlando, 2008; pp. 699-700.
45. Haslam DB, St. Geme JWIII. Enterococcus Species. In Principles and Practice of Pediatric Infectious Diseases, Third Edition. (eds. Long SS, Pickering LK, Prober CG). Harcourt, Inc., Orlando, 2008; pp. 716-719.
46. Haslam DB, St. Geme JWIII. Viridans Streptococci, Abiotrophia and Granulicatella Species, and Streptococcus bovis,. In Principles and Practice of Pediatric Infectious Diseases, Third Edition. (eds. Long SS, Pickering LK, Prober CG). Harcourt, Inc., Orlando, 2008; pp. 719-723.
47. Haslam DB, St. Geme JWIII. Groups C and G Streptococci. In Principles and Practice of Pediatric Infectious Diseases, Third Edition. (eds. Long SS, Pickering LK, Prober CG). Harcourt, Inc., Orlando, 2008; pp. 723-725.
48. Haslam DB, St. Geme JWIII. Other Gram-Positive, Catalase-Negative Cocci: Leuconostocs and Pediococci. In Principles and Practice of Pediatric Infectious Diseases, Third Edition. (eds Long SS, Pickering LK, Prober CG). Harcourt, Inc., Orlando, 2008; pp. 733-734.
49. Hunstad DA, St. Geme JWIII.  Mechanisms of Pediatric Bacterial Disease.  In Pediatric Infectious Diseases: The Requisites in Pediatrics (eds. Bergelson J, Zaoutis T). Elsevier Science, Philadelphia.  2008; pp. 3-11.
50. Hunstad DA, St. Geme JWIII. Molecular Determinants of Microbial Pathogenesis. In Textbook of Pediatric Infectious Diseases, Sixth Edition (eds. Feigin RD, Cherry JD, Kaplan S, Demmler G). WB Saunders, Philadelphia. 2009; pp. 2-21.
51. Camitta MGW, Li JS, St. Geme JWIII. Infective Endocarditis. In Pediatric Practice: Infectious Diseases (ed. Shah S). McGraw-Hill, New York. 2009; pp. 350-367.
52. Sheets AJ, St. Geme JWIII. Nonpilus (Nonfimbrial) Adhesins. In Bacterial Pathogenesis (eds. Locht C, Simonet M). Horizon Press, Norwich, UK. 2011; pp. 99-127.
53. St. Geme JWIII. Haemophilus influenzae. In Principles and Practice of Pediatric Infectious Diseases, Fourth Edition. (eds. Long SS, Pickering LK, Prober CG). Elsevier Saunders, Philadelphia, 2012; pp. 899-905.
54. St. Geme JWIII. Classification of Bacteria. In Principles and Practice of Pediatric Infectious Diseases, Fourth Edition. (eds. Long SS, Pickering LK, Prober CG). Elsevier Saunders, Philadelphia, 2012; pp. 673-675.
55. Haslam DB, St. Geme JWIII. Classification of Streptococci. In Principles and Practice of Pediatric Infectious Diseases, Fourth Edition. (eds. Long SS, Pickering LK, Prober CG). Elsevier Saunders, Philadelphia, 2012; pp. 695-697.
56. Haslam DB, St. Geme JWIII. Enterococcus Species. In Principles and Practice of Pediatric Infectious Diseases, Fourth Edition. (eds. Long SS, Pickering LK, Prober CG). Elsevier Saunders, Philadelphia, 2012; pp. 712-716.
57. Haslam DB, St. Geme JWIII. Viridans Streptococci, Abiotrophia and Granulicatella Species, and Streptococcus bovis. In Principles and Practice of Pediatric Infectious Diseases, Fourth Edition. (eds. Long SS, Pickering LK, Prober CG). Elsevier Saunders, Philadelphia, 2012; pp. 716-719.
58. Haslam DB, St. Geme JWIII. Groups C and G Streptococci. In Principles and Practice of Pediatric Infectious Diseases, Fourth Edition. (eds. Long SS, Pickering LK, Prober CG). Elsevier Saunders, Philadelphia, 2012; pp. 719-721.
59. Haslam DB, St. Geme JWIII. Other Gram-Positive, Catalase-Negative Cocci: Leuconostocs and Pediococci. In Principles and Practice of Pediatric Infectious Diseases, Fourth Edition. (eds. Long SS, Pickering LK, Prober CG). Elsevier Saunders, Philadelphia, 2012; pp. 729-730.
60. St. Geme JWIII. Hap Gene Product of Haemophilus influenzae. In Handbook of Proteolytic Enzymes, Third Edition. (eds. Rawlings ND, Salvesen GS). Elsevier Academic Press, Oxford, 2013; pp. 3099-3102.
61. Plaut A, St. Geme JWIII. Lactoferrin. In Handbook of Proteolytic Enzymes, Third Edition. (eds. Rawlings ND, Salvesen GS). Elsevier Academic Press, Oxford, 2013; pp. 3635-3640.
62. Hunstad DA, Jhaveri R, St. Geme JWIII. Molecular Determinants of Microbial Pathogenesis. In Textbook of Pediatric Infectious Diseases, Seventh Edition (eds. Cherry JD, Kaplan S, Demmler G, Steinbach W). WB Saunders, Philadelphia. 2014, pp. 3-21.
63. Porsch E, Starr K, St. Geme JWIII. Kingella kingae.  In Textbook of Pediatric Infectious Diseases, Seventh Edition (eds. Cherry JD, Kaplan S, Demmler G, Steinbach W). WB Saunders, Philadelphia. 2014, pp. 1699-1704.
64. Camitta MGW, St. Geme JWIII, Li JS. Diagnosis and management of infective endocarditis. In Pediatric Cardiology, Cardiac Surgery and Intensive Care. Springer, New York, NY. 2013, pp. 2307-2327.
65. St. Geme, JWIII. Kingella kingae Infections. In Red Book, 30th Edition (eds. American Academy of Pediatrics Committee on Infectious Diseases). American Academy of Pediatrics, Elk Grove Village, IL. 2015, pp. 500-501.
66. St. Geme JWIII, Rempe KA. Haemophilus influenzae. In Principles and Practice of Pediatric Infectious Diseases, Fifth Edition. (eds. Long SS, Prober CG, Fischer M). Elsevier, Philadelphia. 2018, pp. 926-931.
67. St. Geme JWIII, Rempe KA. Classification of Bacteria. In Principles and Practice of Pediatric Infectious Diseases, Fifth Edition. (eds. Long SS, Prober CG, Fischer M). Elsevier, Philadelphia. 2018, pp. 690-692.
68. Haslam DB, St. Geme JWIII. Classification of Streptococci. In Principles and Practice of Pediatric Infectious Diseases, Fifth Edition. (eds. Long SS, Prober CG, Fischer M). Elsevier, Philadelphia, 2018, pp. 712-714.
69. Haslam DB, St. Geme JWIII. Enterococcus Species. In Principles and Practice of Pediatric Infectious Diseases, Fifth Edition. (eds. Long SS, Prober CG, Fischer M). Elsevier, Philadelphia. 2018, pp. 729-732.
70. Haslam DB, St. Geme JWIII. Viridans Streptococci, Abiotrophia and Granulicatella Species, and Streptococcus bovis Group. In Principles and Practice of Pediatric Infectious Diseases, Fifth Edition. (eds. Long SS, Prober CG, Fischer M). Elsevier, Philadelphia. 2018, pp. 732-735.
71. Haslam DB, St. Geme JWIII. Groups C and G Streptococci. In Principles and Practice of Pediatric Infectious Diseases, Fifth Edition. (eds. Long SS, Prober CG, Fischer M). Elsevier, Philadelphia. 2018, pp. 736-737.
72. Haslam DB, St. Geme JWIII. Other Gram-Positive, Catalase-Negative Cocci: Leuconostocs and Pediococci. In Principles and Practice of Pediatric Infectious Diseases, Fifth Edition. (eds. Long SS, Prober CG, Fischer M). Elsevier, Philadelphia. 2018, pp. 746-747.
73. Hunstad DA, Jhaveri R, Odom John AR, St. Geme JWIII. Molecular Determinants of Microbial Pathogenesis. In Textbook of Pediatric Infectious Diseases, Eighth Edition (eds. Cherry JD, Kaplan SL, Harrison GJ, Steinbach WJ, Hotez PJ). Elsevier, Philadelphia. 2018, pp. 2-15.
74. Porsch EA, St. Geme JWIII. Kingella kingae.  In Textbook of Pediatric Infectious Diseases, Eighth Edition (eds. Cherry JD, Kaplan SL, Harrison GJ, Steinbach WJ, Hotez PJ). Elsevier, Philadelphia. 2018, pp. 1222-1228.
75. St. Geme, JWIII. Kingella kingae Infections. In Red Book, 31st Edition (eds. American Academy of Pediatrics Committee on Infectious Diseases). American Academy of Pediatrics, Elk Grove Village, IL. 2018, pp. 497-498.
76. Kadry N, St. Geme JWIII. Haemophilus influenzae. In Principles and Practice of Pediatric Infectious Diseases, Sixth Edition. (eds. Long SS, Prober CG, Fischer M, Kimberlin D). Elsevier, Philadelphia. 2022, pp. 945-951.
77. Sacharok A, St. Geme JWIII. Classification of Bacteria. In Principles and Practice of Pediatric Infectious Diseases, Sixth Edition. (eds. Long SS, Prober CG, Fischer M, Kimberlin D). Elsevier, Philadelphia. 2022, pp. 708-710.
78. Haslam DB, St. Geme JWIII. Classification of Streptococci. In Principles and Practice of Pediatric Infectious Diseases, Sixth Edition. (eds. Long SS, Prober CG, Fischer M, Kimberlin D). Elsevier, Philadelphia. 2022, pp. 730-731.
79. Haslam DB, St. Geme JWIII. Enterococcus Species. In Principles and Practice of Pediatric Infectious Diseases, Sixth Edition. (eds. Long SS, Prober CG, Fischer M, Kimberlin D). Elsevier, Philadelphia. 2022, pp. 745-748.
80. Haslam DB, St. Geme JWIII. Viridans Streptococci, Abiotrophia and Granulicatella Species, and Streptococcus bovis Group. In Principles and Practice of Pediatric Infectious Diseases, Sixth Edition. (eds. Long SS, Prober CG, Fischer M, Kimberlin D). Elsevier, Philadelphia. 2022, pp. 748-751.
81. Haslam DB, St. Geme JWIII. Groups C and G Streptococci. In Principles and Practice of Pediatric Infectious Diseases, Sixth Edition. (eds. Long SS, Prober CG, Fischer M, Kimberlin D). Elsevier, Philadelphia. 2022, pp. 752-753.
82. Haslam DB, St. Geme JWIII. Other Gram-Positive, Catalase-Negative Cocci: Leuconostocs and Pediococci. In Principles and Practice of Pediatric Infectious Diseases, Sixth Edition. (eds. Long SS, Prober CG, Fischer M, Kimberlin D). Elsevier, Philadelphia. 2022, pp. 762-763.
83. Hunstad DA, Odom John AR, St. Geme JWIII. Molecular Determinants of Microbial Pathogenesis. In Textbook of Pediatric Infectious Diseases, Ninth Edition (eds. Cherry JD, Kaplan SL, Harrison GJ, Steinbach WJ, Hotez PJ). Elsevier, Philadelphia. In Press.

Original Publications, Peer-reviewed as Member of American Board of Pediatrics Research Advisory Committee, Participation Cited but Not by Authorship:

1.         Freed GL, Dunham KM, Althouse LA, American Board of Pediatrics Research Advisory Committee of the American Board of Pediatrics. Characteristics of general and subspecialty pediatricians who choose not to recertify. Pediatrics. 2008;121:711-717

2.         Freed GL, Dunham KM, Jones MD Jr, McGuinness GA, Althouse L, Research Advisory Committee of the American Board of Pediatrics.  General pediatrics resident perspectives on training decisions and career choice. Pediatrics. 2009;123 Suppl 1:S26-30.

3.         Freed GL, Dunham KM, Swiatalski KE, Jones MD Jr., McGuinness GA, Research Advisory Committee of the American Board of Pediatrics. Pediatric fellows: Perspectives on training and future scope of practice. Pediatrics. 2009;123 Suppl 1:S31-37.

4.         Freed GL, Dunham KM, Switalski KE, Jones MD Jr., McGuinness GA, Research Advisory Committee of the American Board of Pediatrics. Recently trained general pediatricians:  Perspectives on training and scope of practice. Pediatrics. 2009;123 Suppl 1:S38-43

5.         Freed GL, Dunham KM, Switalski KE, Jones MD Jr., McGuinness GA, Research Advisory Committee of the American Board of Pediatrics. Recently trained pediatric subspecialists:  Perspectives on training and scope of practice. Pediatrics. 2009;123 Suppl 1:S44-49.

6.         Freed GL, Dunham KM, Abraham L, Research Advisory Committee of the American Board of Pediatrics. Protecting the public: State medical board licensure policies for active and inactive physicians. Pediatrics. 2009;123:643-652.

7.         Freed GL, Dunham KM, Research Advisory Committee of the American Board of Pediatrics. Pediatric hospitalists: Training, current practice, and career goals. Journal of Hospital Medicine. 2009;4:179-186.

8.         Freed GL, Dunham KM, Research Advisory Committee of the American Board of Pediatrics. Characteristics of pediatric hospital medicine fellowship and training programs. Journal of Hospital Medicine. 2009;4:157-163.

9.         Freed GL, Dunham KM, Switalski EK, Research Advisory Committee of the American Board of Pediatrics. Assessing the value of pediatric hospitalist programs: The perspective of hospital leaders. Academic Pediatrics. 2009;9:192-196.

10.     Freed GL, Dunham KM, Lamarand KE, Research Advisory Committee of the American Board of Pediatrics. Permanent pediatric diplomate awareness of and perspectives on maintenance of certification. Journal of Pediatrics. 2009;155:919-923.

11.     Freed GL, Dunham KM, Lamarand KE, Research Advisory Committee of the American Board of Pediatrics. Hospitalists’ involvement in pediatrics training: Perspectives from pediatric residency program and clerkship directors. Academic Medicine. 2009;84:1617-1621.

12.     Freed GL, Dunham KM, Research Advisory Committee of the American Board of Pediatrics. All primary care trainees are not the same: The role of economic factors and career choice. Pediatrics. 2010;125:574-577

13.     Freed GL, Dunham KM, Clark SJ, Davis MM, Research Advisory Committee of the American Board of Pediatrics.  Perspectives and preferences among the general public regarding physician selection and board certification. Journal of Pediatrics. 2010;156:841-845.

14.     Freed GL, Dunham KM, Gebremariam A, Wheeler JR, Research Advisory Committee of the American Board of Pediatrics. Which pediatricians are providing care to America’s children? An update on the trends and changes during the past 26 years. Journal of Pediatrics. 2010;157:148-152.

15.     Freed GL, Dunham KM, Loveland-Cherry CJ, Martyn KK, Research Advisory Committee of the American Board of Pediatrics. Pediatric nurse practitioners in the United States: Current distribution and recent trends in training. Journal of Pediatrics. 2010;157:589-593.

16.     Freed GL, Dunham KM, Lamarand KE, Loveland-Cherry C, Martyn KK, American Board of Pediatrics Research Advisory Committee. Neonatal nurse practitioners: Distribution, roles and scope of practice. Pediatrics. 2010;126:856-860.

17.     Freed GL, Dunham KM, Loveland-Cherry C, Martyn KK, American Board of Pediatrics Research Advisory Committee. Family nurse practitioners: Roles and scope of practice in the care of pediatric patients. Pediatrics. 2010;126:861-864.

18.     Freed GL, Dunham KM, Moote MJ, Lamarand KE, American Board of Pediatrics Research Advisory Committee.  Pediatric physician assistants: Distribution and scope of practice. Pediatrics. 2010;126:851-855.

19.     Freed GL, Dunham KM, Lamarand KE, Loveland-Cherry C, Martyn KK, American Board of Pediatrics Research Advisory Committee. Pediatric nurse practitioners: Roles and scope of practice. Pediatrics. 2010;126:846-850.

20.     Freed GL, Dunham KM, Loveland-Cherry C, Martyn KK, Moote MJ, American Board of Pediatrics Research Advisory Committee. Nurse practitioners and physician assistants employed by general and subspecialty pediatricians. Pediatrics 2011;128:665-672.

21.     Freed GL, Dunham KM, Loveland-Cherry C, Martyn KK, Moote MJ, American Board of Pediatrics Research Advisory Committee. Private practice rates among pediatric subspecialists. Pediatrics. 2011;128:673-676.

22.     Freed GL, Dunha KM, Moran LM, Spera L., Research Advisory Committee of the American Board of Pediatrics. Resident work hour changes in children’s hospitals: Impact on staffing patterns and workforce needs. Pediatrics. 2012;130:700-704.

23.     Freed GL, Dunham KM, Martyn K, Martin J, Moran LM, Spera L, Research Advisory Committee of the American Board of Pediatrics. Pediatric nurse practitioners: Influences on career choice. Journal of Pediatric Health Care. 2014;28:114-120.

24.     Freed GL, Moran LM, Dunham KM, Hawkins-Walsh E, Martyn KK, Research Advisory Committee of the American Board of Pediatrics. Capacity of, and demand for, pediatric nurse practitioner educational programs: A missing piece of the workforce puzzle.  Journal of Professional Nursing. 2015;31:311-317.

25.     Freed GL, Moran LM, Dunham KM, Nantais-Smith L, Martyn KK, Research Advisory Committee of the American Board of Pediatrics. Capacity of, and demand for, neonatal nurse practitioner educational programs: A missing piece of the workforce puzzle. Journal of Professional Nursing. 2015;31:318-322.

26.     Freed GL, Moran LM, Althouse LA, Van KD, Leslie LK; Research Advisory Committee of the American Board of Pediatrics. Jobs and career plans of new pediatric subspecialists. Pediatrics. 2016;137:1-10.

27.     Freed GL, Moran LM, Van KD, Leslie LK; Research Advisory Committee of the American Board of Pediatrics. Current workforce of general pediatricians in the United States. Pediatrics. 2016 Apr;137(4). pii: e20154242. doi: 10.1542/peds.2015-4242.

28.     Freed GL, Moran LM, Van KD, Leslie LK; Research Advisory Committee of the American Board of Pediatrics. Current Workforce of Pediatric Subspecialists in the United States. Pediatrics. 2017 May;139(5). pii: e20163604.doi: 10.1542/peds.2016-3604.

Books

1. Housestaff Manual: Well Child Care, Editors Carraccio C, St. Geme JWIII. Ross Laboratories, Columbus, Ohio, 1987.
2. Nelson Textbook of Pediatrics, Nineteenth Edition, Editors Kliegman RM, Stanton BMD, St. Geme JWIII, Schor N, Behrman RE. Elsevier, Inc., 2011.
3. Nelson Textbook of Pediatrics, Twentieth Edition, Editors Kliegman RM, Stanton BMD, St. Geme JWIII, Schor N. Elsevier, Inc., 2015.
4. Advances in Understanding Kingella kingae. Editor, St. Geme JWIII. Springer International Publishing, 2016.
5. Nelson Textbook of Pediatrics, Twenty first Edition, Editors Kliegman RM, St. Geme JWIII, Blum N, Shah S, Tasker RC, Wilson K. Elsevier, Inc., 2019.
6. Nelson Textbook of Pediatrics, Twenty second Edition, Editors Kliegman RM, St. Geme JWIII, Blum N, Tasker RC, Wilson K, Deardorff M, Schuh A. Elsevier, Inc., In Press.

Letters, Commentaries, Book Reviews:

1. St. Geme JWIII, Hyman D. Hepatic injury during rotavirus infections.  Journal of Pediatrics 1988;113:952-953 (letter).
2. St. Geme JWIII. Neurology for Non-Neurologists, by Wigbert Wiederholt, WB Saunders, Pediatric Dermatology. 1989:6:58 (Book review).
3. St. Geme JWIII. MOC: A Catalyst for QI work. ABMS Insights. 2017 Fall.

Major Invited Professorships and Lectureships:

1991              American Academy of Pediatrics Spring Meeting, Plenary Session, February 1991: “Haemophilus influenzae: Update on pathogenesis and prevention of disease.”

1991              National Institute of Child Health and Human Development Conference on Perinatal and Neonatal Medicine, August 1991: “The Pediatric Scientist Training Program.”

1991              University of Texas, Southwestern School of Medicine lecture series in Microbiology and Infectious Diseases, November 1991: “Interactions between Haemophilus influenzae and the human host.”

1991              Stanford University School of Medicine Department of Pediatrics Grand Rounds, December 1991: “Haemophilus influenzae: recent successes and future challenges.”

1994              Washington University School of Medicine Department of Pediatrics Grand Rounds, January 1994: “Haemophilus influenzae disease: recent successes, future challenges.”

1995              St. Louis Children's Hospital, Early Bird Rounds, January 1995: “1994 Highlights in Pediatric Infectious Diseases.”

1995              Gordon Research Conference on Mechanisms of Microbial Adherence and Signalling, June 1995: “Interrelationship between pili, fibrils, and capsule in adherence by Haemophilus influenzae type b.”

1995              State University of New York at Stony Brook Department of Pediatrics Grand Rounds, April 1995: “Haemophilus influenzae disease: recent successes and future challenges.”

1995              University of Minnesota Topics in Pediatrics Continuing Medical Education Course, June 1995: “The role of nontypable Haemophilus influenzae in disease.”

1996              Transatlantic Airway Conference, January 1996: “Haemophilus influenzae adhesins.”

1996              MedImmune, Inc. March 1996: “Molecular determinants of the interaction between Haemophilus influenzae and human cells.”

1996              Washington University School of Medicine Continuing Medical Education Course, March 1996: “Otitis media and sinusitis: vaccination as a strategy for prevention.”

1996              American Academy of Pediatrics Continuing Medical Education Course, June 1996: “Rickettsial infections: old and new.”

1996              American Academy of Pediatrics Continuing Medical Education Course, June 1996: “The myriad manifestations of Parvovirus B19 infection.”

1996              American Academy of Pediatrics Continuing Medical Education Course, June 1996: “Parasites and the day care center.”

1996              American Academy of Pediatrics Continuing Medical Education Course, June 1996: “Antibiotic resistance.”

1996              Wyeth-Lederle Vaccines and Pediatrics, December 1996: “Characterization of the Haemophilus influenzae Hap protein.”

1997              Pediatric Infectious Diseases Society Annual Symposium, May 1997: “Mechanisms of colonization by nontypable Haemophilus influenzae.”

1997              SUNY Buffalo Microbial Pathogenesis Seminar Series; June 1997: “Molecular determinants of the interaction between Haemophilus influenzae and human epithelium.”

1997              Gordon Research Conference on Microbial Adhesion and Signalling, August 1997: “Hap-mediated adherence by Haemophilus influenzae.”

1998              University of Florida Department of Pediatrics Grand Rounds, January 1998: “Haemophilus influenzae type b: a paradigm.”

1998              University of Florida Department of Pediatrics, January 1998: “Exanthems: More than skin deep.”

1998              University of Florida Department of Pediatrics, January 1998: “Upper respiratory infections and antibiotic resistance.”

1998              Association of American Medical School Pediatric Department Chairmen Frontiers in Science Program, March 1998: “The molecular mechanism of Haemophilus influenzae pathogenicity.”

1998              Southern Illinois University Edwardsville Schools of Medicine and Nursing Continuing Medical Education Course, April 1998: “Emerging infections in the United States.”

1998              Washington University School of Medicine Department of Genetics Seminar Series, May 1998: “Molecular determinants of Haemophilus influenzae pathogenicity.”

1998              St. Louis Children's Hospital, Early Bird Rounds, June 1998: “Emerging infections.”

1998              Midwest Microbial Pathogenesis Meeting, September 1998: “Molecular determinants of the interaction between Haemophilus influenzae and respiratory epithelium.”

1999              University of Texas, Southwestern Department of Microbiology Seminar, March 1999: “Molecular determinants of Haemophilus influenzae pathogenicity.”

1999              7th International Symposium on Recent Advances in Otitis Media, June 1999: “Molecular determinants of colonization by nontypable Haemophilus influenzae.”

1999              Gordon Research Conference on Molecular Mechanisms of Microbial Adherence, August 1999: “Secretion of nontypable Haemophilus influenzae adhesins: Variations on a common theme.”

1999              St. Louis Children's Hospital, Early Bird Rounds, September 1999: “Treatment of otitis media in the era of antibiotic resistance.”

1999              Infectious Diseases Society of America Annual Meeting, November 1999: “Pathogenesis of nontypable Haemophilus influenzae disease.”

1999              Washington University School of Medicine, Pulmonary Grand Rounds, December 1999: “Bacterial and host determinants of Haemophilus influenzae disease.”

2000              International Symposium on 'Otitis Media: A Preventable Disease?', February 2000: “The pathogenesis of nontypable Haemophilus influenzae otitis media.”

2000              University of Iowa, Department of Microbiology Seminar, March 2000: “Molecular determinants of Haemophilus influenzae disease.”

2000              University of Alabama, Birmingham, Department of Microbiology Seminar, April 2000: “Molecular pathogenesis of nontypable Haemophilus influenzae disease.”

2000              University of Alabama, Birmingham, Department of Microbiology, Microbial Pathogenesis course, April 2000: “Molecular determinants of bacterial adherence and colonization.”

2000              Washington University School of Medicine Department of Pediatrics Grand Rounds, April 2000: “The protective effects of human milk.”

2000              Stanford University School of Medicine, Infectious Disease Grand Rounds, September 2000: “Haemophilus influenzae: A host-adapted pathogen.”

2000              Stanford University School of Medicine Department of Pediatrics Grand Rounds, September 2000: “The protective effects of human milk.”

2000              2nd Annual Statement of “Cutting Edges in Pediatric Infectious Diseases,” October 2000: “Haemophilus influenzae disease:  A dynamic process.”

2000              Medical College of Wisconsin, Department of Pathology Seminar Series, November 2000: “Molecular determinants of Haemophilus influenzae pathogenicity.”

2000              University of Cincinnati, Department of Pediatrics and Children's Hospital Research Foundation, Special Seminar, November 2000: “Haemophilus influenzae: A model mucosal pathogen.”

2001              Cedars-Sinai Medical Center, Department of Pediatrics, Ben Kagan Lectureship, May 2001: “Recent successes and future opportunities for childhood vaccines.”

2001              Children's Hospital of Philadelphia, Department of Pediatrics Grand Rounds, October 2001: “The protective effects of human milk.”

2002              Wyeth Vaccines, March 2002: “Adhesive and proteolytic activity of the Haemophilus influenzae Hap protein.”

2002              International Pasteurellaceae Society Meeting, May 2002: “Molecular determinants of Haemophilus influenzae colonization.”

2002              Annual Meeting of the American Society for Microbiology, May 2002: “Molecular determinants of Haemophilus influenzae disease.”

2002              Annual Meeting of the American Society for Microbiology, May 2002: “Structure and function of the Haemophilus influenzae Hia autotransporter.”

2002              Research Rounds, August 2002: “How to prepare a successful grant application.”

2002              Research Rounds, August 2002: “The use of molecular tools in the management of infectious diseases.”

2002              University of Houston, Department of Biology Seminar Series, November 2002, “Haemophilus influenzae:  A model mucosal pathogen.”

2003              David Hinds Memorial Lecture, Annual Meeting of Clinical Microbiologists from Pediatric Health Care Facilities, Annual Meeting of the American Society for Microbiology, May 2003:  “Nontypable Haemophilus influenzae:  From pathogenesis to vaccine development.”

2003              Chiron, Siena, Italy, June 2003, “Nontypable Haemophilus influenzae: From pathogenesis to vaccine development.”

2003              Annual Meeting of the Infectious Diseases Society of America, October 2003, “Nontypable Haemophilus influenzae: balance between commensal and pathogen.”

2004              Washington University School of Medicine Department of Pediatrics Grand Rounds, April 2004: “Haemophilus influenzae disease: Lessons learned and prospects for the future.”

2004              Baylor College of Medicine, Infectious Diseases Seminar Series, April 2004: “Nontypable Haemophilus influenzae: A host adapted pathogen.”

2004              Annual Meeting of the Infectious Diseases Society of America, September 2004, “Top 10 New and Emerging Topics in Pediatric Infectious Diseases.”

2004              Duke University Medical Center, Department of Pediatrics Special Lecture, October 2004: “Haemophilus influenzae disease:  Lessons learned and prospects for the future.”

2005              University of Alabama, Birmingham, Department of Microbiology Seminar, April 2005: “Type V secretion and Haemophilus influenzae pathogenicity.”

2005              University of Alabama, Birmingham, Department of Microbiology, Microbial Pathogenesis course, April 2005: “Community-acquired methicillin-resistant Staphylococcus aureus: An emerging pathogen.”

2005              Annual Meeting of the Infectious Diseases Society of America, October 2005, “Top 10 New and Emerging Topics in Pediatric Infectious Diseases.”

2006              Annual St. Jude Children’s Research Hospital-PIDS Pediatric Infectious Diseases Research Conference, February 2006, “Structural determinants of Haemophilus influenzae pathogenicity.”

2006              Katz-Wilfert Pediatric Infectious Diseases Update, April 2006: “Update on acute otitis media”

2006              Annual Meeting of the American Society for Microbiology, May 2006: “Surface tethering of the Haemophilus influenzae HMW1 adhesin”

2006              University of Minnesota Lewis Wannamaker Memorial Lecture, June 2006, “Otitis media: changing epidemiology and prospects for the future.”

2006              University of Oklahoma Department of Pediatrics Harris D. Riley Lecture, September 2006, “Otitis media: changing epidemiology and prospects for the future.”

2006              Annual Meeting of the Infectious Diseases Society of America, October 2006, “Top 10 New and Emerging Topics in Pediatric Infectious Diseases.”

2006              University of Michigan Department of Microbiology and Immunology Post-Doctoral Fellows Invited Seminar, October 2006, “Type V secretion and the pathogenesis of Haemophilus influenzae disease.”

2006              Alexander Spock Symposium in Pediatrics, November 2006, “Changes in childhood immunizations and other hot topics in infectious diseases.”

2007              University of Washington Fellows’ Research Day, April 2007, “Bench to bedside research: role of CTSAs.”

2007              University of Washington Department of Pediatrics Grand Rounds, April 2007, “Conjugate vaccines: recent impact and future prospects.”

2007              Stanford University Department of Pediatrics Norman Kretchmer Lecture, September 2007, “Conjugate vaccines: recent impact and future prospects.”

2007              Annual Meeting of the Infectious Diseases Society of America, October 2007, “New and Emerging Topics in Pediatric Infectious Diseases.”

2007              Moses Cone Hospital Pediatric Grand Rounds, December 2007, “Osteoarticular infections in young children: a changing of the guard.”

2008              Morgan Stanley Children’s Hospital and Columbia University Department of Pediatrics Grand Rounds, April 2008, “Osteoarticular infections in young children: a changing of the guard.”

2008              Annual Meeting of the American Society for Microbiology, June 2008: “Secretion and structure of Haemophilus influenzae adhesins.”

2008              University of Colorado, Infectious Diseases and Microbiology Conference, November 2008, “Osteoarticular infections in young children: a changing of the guard.”

2008              University of Colorado Joseph W. St. Geme, Jr. Memorial Lecture, November 2008, “Bacterial versatility: relationship between commensalism and disease.”

2008              Medical College of Wisconsin Department of Pediatrics Grand Rounds, November 2008, “Osteoarticular infections in young children: a changing of the guard.”

2008              Children’s Hospital of Wisconsin Starkey Davis Conference, Keynote Lecture, November 2008, “Hot Topics in Pediatric Infectious Diseases: 2008.”

2009              Vanderbilt University Department of Pediatrics Grand Rounds, March 2009, “Bacterial versatility and the balance between commensalism and disease.”

2009              Children’s Hospital of Philadelphia Department of Pediatrics Grand Rounds, April 2009, “Osteoarticular infections in young children: a changing of the guard.”

2009              Buffalo Microbial Pathogenesis Conference, April 2009, “Trimeric autotransporters and Haemophilus pathogenicity.”

2009              University of North Carolina at Chapel Hill Department of Microbiology and Immunology Seminar Series, December 2009, “Trimeric autotransporters and Haemophilus pathogenicity.”

2010              Duke University School of Medicine Hippocratic Oath Ceremony, May 2010, “Lessons Learned and the Joy of the Journey.”

2010              Annual Meeting of the Infectious Diseases Society of America, October 2010, “Fellow to Faculty Transition.”

2011              Pittsburgh Children’s Hospital Child Health Research Center of Excellence Retreat, April 2011, “Bacterial versatility and the balance between commensalism and disease.”

2012              University of Florida Department of Pediatrics Elia Ayoub Memorial Lecture, April 2012, “Osteoarticular infections in young children: new faces.”

2012              University of California at San Diego Department of Pediatrics Grand Rounds, September 2012, “New faces in osteoarticular infections in young children.”

2012              University of North Carolina – Chapel Hill Department of Pediatrics Grand Rounds, October 2012, “New faces in osteoarticular infections in young children.”

2013              University of California at San Francisco, Microbial Pathogenesis Seminar Series, February 2013, “Kingella kingae, an emerging pediatric pathogen.”

2013              Children’s Hospital Boston Department of Medicine Grand Rounds, April 2013, “The changing face of osteoarticular infections in young children.”

2013              Infectious Diseases Week Annual Meeting, October 2013, Fellows Day, “Finding a faculty position.”

2013              Infectious Diseases Week Annual Meeting, October 2013, “Hot topics in pediatric infectious diseases.”

2014              University of Pennsylvania, Prokaryotic Seminar Series, February 2014, “Insights into Kingella kingae, an emerging pediatric pathogen.”

2014              Montefiore Hospital, Department of Pediatrics Grand Rounds, Department of Pediatrics Research Day, April 2014, “New insights into an emerging bacterial pathogen.”

2014              The Children’s Hospital of Philadelphia Research Institute Symposium, May 2014, Keynote Address

2014              Children’s Hospital of Los Angeles, Department of Pediatrics Grand Rounds, September 2014, “The changing face of osteoarticular infections in young children.”

2014              Stanford University Department of Pediatrics Lawrence G. Crowley Distinguished Lecture in Pediatrics, October 2014, “The changing face of osteoarticular infections in young children.”

2015              The Children’s Hospital of Philadelphia Summer Scientific Research Colloquium, July 2015, “In pursuit of how bacteria cause disease.”

2016              University of California, Los Angeles Department of Pediatrics Grand Rounds, April 2016, “Kingella kingae: An emerging pediatric pathogen.”

2016              Pediatric Academic Societies Annual Meeting, May 2016, “Meeting clinical regulatory requirements despite limited clinical time.  Resources needed by physician scientists.”

2016              Columbia University Department of Pediatrics Hattie Alexander Memorial Lecture, May 2016, “Insights into an emerging pathogen reminiscent of Haemophilus influenzae type b.”

2017              University of Vermont Department of Molecular Genetics and Microbiology Seminar Series, April 2017, “Molecular Determinants of Disease Due to Kingella kingae, an Emerging Pediatric Pathogen.”

2017              Children’s Hospital of Philadelphia Department of Pediatrics Grand Rounds, July 2017: “Medical Education at CHOP: A View to the Future.”

2018              University of Iowa Stead Department of Pediatrics Research Day, April 2018, “Kingella kingae: An Emerging Pediatric Pathogen.”

2018              University of Texas Southwestern Medical Center Department of Microbiology Seminar Series, April 2018, “Molecular Determinants of Disease Due to Kingella kingae, an Emerging Pediatric Pathogen.”

2019              St. Jude/PIDS Pediatric Infectious Diseases Research Conference, Luminary in Pediatric Infectious Diseases Lecture, March 2019, “Kingella kingae Pathogenicity: Just a Spoonful of Sugar.”

2019              St. Jude/PIDS Pediatric Infectious Diseases Research Conference, March 2019, “Leadership Positions.”

2019              Washington University Department of Pediatrics Donald Thurston Distinguished Lecture in Pediatrics, March 2019, “Insights into the Determinants of Bacterial Pathogenicity.”

2021              Association of Medical School Pediatric Department Chairs Research Series for Trainees, January 2021, “Common Themes in Invasive Bacterial Disease in Children.”

2021              New York University Saul Krugman Memorial Lecture, May 2021, “Insights into Determinants of Bacterial Pathogenicity.”

2022              BPD Collaborative Annual Meeting, March 2022, “Multicenter Networks – Career Development.”

Teaching Responsibilities Including Continuing Education:

Washington University Medical Students (1992-2005)

Lecturer:

                       New Diseases, New Pathogens Mini-course (course #MO4 526)

                       Microbes and Pathogenesis (course #M30 526)

                       Infectious Diseases & Medical Microbiology (course #M25 605A)

                       Introduction to Clinical Medicine (Pediatric Infectious Diseases)

Coursemaster:

                       Clerkship in Pediatric Infectious Diseases (course #M65 840)

Teaching Attending:

                       Core clerkship in Pediatrics

                       Clerkship in Pediatric Infectious Diseases (course #M65 840)

Faculty Advisor:

                       Student-Directed Immunization Drive (2000)

Research Rotation Mentor:

                       Robert Shih (1999)

Duke University Medical Students (2005-2013)

Teaching Attending:

              Core clerkship in Pediatrics

              Clerkship in Pediatric Infectious Diseases

Research Year Mentor:

              Juliana Gao (2012-2013)

Pediatric Interest Group

University of Pennsylvania Medical Students (2013-present)

Teaching Attending:

              Core clerkship in Pediatrics

              Clerkship in Pediatric Infectious Diseases

Cornfeld Society (Pediatric Interest Group)

Washington University Graduate Students (1992-2005)

Lecturer:

                       Special Topics in Microbial Pathogenesis (course #L41 5217)

                       Molecular Microbiology and Pathogenesis (course #L41 5392)

Qualifying Exam Committee:

                       Rebecca Stith, Michelle Michalski, Mara Lippa, Brian Cobb, Avelina Espinosa, Natasha Ruiz, Evan Saulino, Michelle Barnhart, Tracie Hudson, Fred Sauer, Paula Revell, Jenny Lovett, Joshua Madden, Althea Capul, Travis Jewitt, Jessica Sexton, Benjamin Buscher, Elizabeth Fossman, Matt Lawlor, Gregory Anderson, Stacey Meyers, Michael Meehl, Joseph Ippolito, Charles Rexer, Carr Vincent, Chris Marion, Richard Weart, Jason Rosch, Paul Davis, Darby Mahan, Ashley Nenninger, Ting Tao, Sarah Witowski, Buck Samuel, Colin Kietzman, Amy Lee, Diane Alexander

Ph.D. Thesis Committee:

                       Janice Dobrowolski, David Provence, George Fogg, Carmella Gibson, Kathy Kolakovich, David Hendrixson, Suzanne Dawid, Danielle Hung, Evan Saulino, Gabriel Soto, William Lyon, Rebecca Lyon, Paula Revell, Juan Martinez, Fred Sauer, Doran Fink, Michelle Barnhart, Kristin Nelson, Darcy Gill, Yvonne Lee, Amy Zoch Buscher, Neil Surana, Gregory Anderson, Hyun-Jeong Ra, Heidi Rayala, Matt Lawlor, Lloyd Robinson, Michael Meehl, Mythili Suntharalingam, Shane Cotter, Carr Vincent, Andrew Kau, Eric Miller, Jennifer Loughman, Jason Rosch, Darby Mahan, Jason Cathelyn, Shirly Mildner, Jun Liu, Ashley Nenninger, Scott Handley, Kelly Wright, Marisa Ponpuak

Research Rotation Mentor:

                       David Hendrixson, Mike Robek, Avelina Espinosa, Tracie Hudson, David Brooks, David Beck, Aleksandra Jegorow, Doran Fink, Dawn Wetzel, Sami Barmada, Amy Zoch, Matt Lawlor, Stacey Meyers, Greg Anderson, Neil Surana, Erin Brosnahan, Benjamin Buscher, Morgann Reilly, Luke Starnes, Colin Kietzman, Thomas Kehl-Fie, Amanda Sheets, Thomas Hannan, Amy Lee, Simren Mehta, Shana Dew, John Beyer

Ph.D. Thesis Advisor:

1994-1999              David R. Hendrixson  (Ph.D. program)

1996-1999              Suzanne Dawid  (M.D., Ph.D. program)

1998-2002              Doran Fink (M.D., Ph.D. program)

1999-2004              Amy Zoch (Ph.D. program)

2000-2004              Neil Surana (M.D., Ph.D. program)

2002-2005              Morgann Reilly (Ph.D. program)

2002-2004              Shane Cotter (M.D., Ph.D. program)

2002-2005              Luke Starnes, (Ph.D. program)

2003-2008              Thomas Kehl-Fie (Ph.D. program)

2004-2005              Amanda Sheets (Ph.D. program)

Duke University Graduate Students (2005-2013)

Lecturer:

              Microbial Pathogenesis (course #MGM 282)

Qualifying Exam Committee:

              Cong Jin, Christian Kunder, Benjamin Mudrak, Bidong Song, Kristen Smith, Matthew Kan, Emily Snavely

Ph.D. Thesis Committee:

              Amanda Sheets, Cong Jin, Christian Kunder, Benjamin Mudrak, Jordan Cocchiaro, Mark Vignola, Nicole Spahich, Bidong Song, Stacey Prow, Tiffany Prest, Eric Porsch, Kimberly Starr, Matthew Kan, Kristen Smith, Emily Snavely, Katherine Rempe

Research Rotation Mentor:

              Marc Frahm, Nicole Spahich, Tiffany Prest, Stacy Prow, Alisha Holtzhausen, Maria Happel, Eric Porsch, Ashley Trama, Kristen Jurcic, Kimberly Starr, Christopher Ward, Katherine Rempe, Bradley Kern, Emily Snavely, Victoria Carpenter

Ph.D. Thesis Advisor:

                            2005-2009              Amanda Sheets (Ph.D. program)

                            2006-2011              Nicole Spahich (Ph.D. program)

                            2008-2012              Eric Porsch (Ph.D. program)             

                            2011-2016              Kimberly Starr (Ph.D. program)

2012-2013              Bradley Kern (Ph.D. program)

                            2012-2016              Katherine Rempe (Ph.D. program)

University of Pennsylvania Graduate Students (2013-present)

Qualifying Exam Committee:

Jeff Kubiak, Elinor Willis, Valeria Reyes-Ruiz, Tzvi Pollock

Ph.D. Thesis Committee:

Bradley Kern, Jeff Kubiak, Vanessa Munoz, Valeria Reyes-Ruiz, Nadia Kadry, Alexandra Perry, Nina Montoya, Daniel Akuma, Daniel Morreale, Kevin Hernandez, Jenny Zhang, Alex Smith, Ying Yang

Research Rotation Mentor:

Valeria Reyes-Ruiz, Vanessa Munoz, Nadia Kadry, Alexandra Perry, Nina Montoya, Daniel Morreale, Kevin Hernandez, Orlaith Keenan, Taylor Yount, Valeria Vigo, Emily O’Rourke

Post-Baccalaureate Advisor:

                            Miguel Rodriguez Anavitate

Ph.D. Thesis Advisor:

                            2013-2018              Bradley Kern (Ph.D. program)

                            2015-2019              Vanessa Munoz (Ph.D. program)

                            2016-2021              Nadia Kadry (Ph.D. program)

                            2016-2021              Alexandra Perry (Ph.D. program)

                            2018-pres              Nina Montoya (Ph.D. program)

                            2020-pres              Kevin Hernandez (Ph.D. program)

                            2020-pres              Dan Morreale (Ph.D. program)

                            2021-pres              Taylor Yount (Ph.D. program)

                            2022-pres              Valeria Vigo (Ph.D. program)

Other Graduate Students

Ph.D. Thesis Committee:

                            Michael Johnson (University of North Carolina-Chapel Hill)

St. Louis Children's Hospital Pediatric Residents (1992-2005)

Teaching Attending:

                       General Pediatrics

                       Elective in Pediatric Infectious Diseases

Residents Report

Duke University Medical Center Pediatric and Medicine/Pediatric Residents (2005-2013)

Teaching Attending:

              General Pediatrics

              Elective in Pediatric Infectious Diseases

Morning Report

Intern Report

The Children’s Hospital of Philadelphia Pediatric and Medicine/Pediatric Residents (2013-Present)

Teaching Attending:

              General Pediatrics

Morning Report

Advanced Skill in Clinical Research

Washington University Post-doctoral Laboratory Trainees (1992-2005)

1993-1995              Maria L. de la Morena, M.D. (present position: Pediatric practice, New York, NY)

1995-1999              Graham P. Krasan, M.D. (present position: Clinical Professor of Pediatrics, Wayne State University, Beaumont Children’s Hospital)

1996-1998              Venkatarama K. Rao, M.D., Ph.D. (present position: Medical director, Division of Tuberculosis Control, Virginia Department of Health; Field Medical Officer, Division of Tuberculosis Elimination, Centers for Disease Control and Prevention)

1999-2002              Gail Hardy, Ph.D. (present position: Associate Scientist, University of Indiana, Department of Biology)

2000-2003              Sven Laarmann, Ph.D. (present position:  Staff Scientist, Carl Zeiss MicroImaging, Göttingen, Germany)

2002-2004                   Michael Koenig, M.D. (present position: Staff Pulmonologist, Akron Children’s Hospital)

2003-2004              Hye-Jeong Yeo, Ph.D. (present position: Professor, University of Houston, Department of Biochemistry)

2003-2005              Deborah Cholon, Ph.D. (present position: Research Associate, University of North Carolina-Chapel Hill)

2004-2005              Eric Martens, Ph.D. (present position: Associate Professor,                                           University of Michigan School of Medicine, Department of Microbiology and Immunology)

Duke University Post-doctoral Laboratory Trainees (2005-present)

2005-2007              Deborah Cholon, Ph.D. (present position: Research Associate, University of North Carolina-Chapel Hill)

2006-2009              Jana Radin, Ph.D. (present position: Research Scientist, University of Illinois School of Medicine)

2006-2009              Roma Kenjale, Ph.D. (present position: Medical Scientist, Syneos Health)

2009-2017              Jessica McCann, Ph.D. (present position: Senior Research Associate, Duke University)

2012-2013              Eric Porsch, Ph.D. (present position: Research Scientist, Children’s Hospital of Philadelphia)

Washington University Undergraduates (1992-2005)

1994-1996              Anita Padmanabhan

1994-1996              Vinitha Kumar

1995-1996              Claudia Schill

1997-1999              Katherine Burmeister

2003-2005              Nicholas Piotrowski

Duke University Undergraduates (2005-Present)

              2009-2011              Sneha Shah

Other Undergraduates

2002                                 Darcey Moschenross

              2006-2007              Elizabeth Grass

              2010-2013              Emily Grass

              2015                            Maria Sermania

              2020                            Miguel Rodriguez

High School Students

2002                                 Sherri Williams (Washington University Young Scientist Program)

Areas of Research Interest:

Host-bacterial interactions

Haemophilus influenzae pathogenicity

Haemophilus influenzae vaccine development

Bacterial protein secretion

Innate immune mechanisms

Kingella kingae pathogenicity

Bacterial surface polysaccharides

Haemophilus cryptic genospecies pathogenicity

Relationship between Haemophilus influenzae colonization and asthma

External Support:

Active

(St. Geme, PI) 1R01 AI121015-01A1                                                                      06/01/16-05/31/22

NIH/NIAID

“Virulence mechanisms in the emerging pathogen Kingella kingae”

The major goals of this project are to elucidate the interrelationship between type IV pili, a trimeric autotransporter adhesin called Knh, and the polysaccharide capsule as determinants of K. kingae adherence; to examine the role of pili, Knh, and capsule in a rhesus macaque monkey colonization model; and to characterize the pathogenic and immunologic properties of the four different K. kingae polysaccharide capsules. 

Role: PI

(St. Geme, PI) K12 HD43494                            4/1/13-11/30/22             

NIH/NICHD

“CHOP Pediatric Scholars Program”

The goal of this project is to provide pediatric physician-scientists who are junior faculty members with mentorship and resources to increase their research skills and to facilitate their development as independent investigators.

Role: PI

(St. Geme, PI) T32 HD43021                            5/1/15-4/30/25                           

NIH/NICHD                                         

CHOP Institutional Training in Pediatric Research         

The goal of this project is to enhance the development of physician-scientists by providing mentorship and research training for fellows in pediatric subspecialties.

Role: PI

Pending

(St. Geme, PI) 1R01AI172841                                                                                    09/01/22-08/31/27

NIH/NIAID

“Pathogenicity of the emerging pathogen Kingella kingae”

The major goals of this project are to elucidate how the K. kingae type 1 and type 2 exopolysaccharides are synthesized and anchored to the bacterial surface, to elucidate the pathogenic properties of the K. kingae type 1 and type 2 exopolysaccharides, and to elucidate the immunogenicity and protective efficacy of the K. kingae exopolysaccharides. 

Role: PI

(priority score 10, 1st percentile, awaiting notice of award)

(St. Geme, PI) 1R01 AI170597                                                       

NIH/NIAID

“Nontypeable Haemophilus influenzae adhesin-based vaccine”

This project will address the hypothesis that a multi-valent vaccine containing the nontypeable H. influenzae (NTHi) Hap, HMW1, HMW2, and Hia adhesins will stimulate both antibody and IL-17A responses and provide high-level protection against nasopharyngeal colonization by all strains of NTHi. The goals of the project are to elucidate whether addition of HMW1/HMW2 to Hap augments protective immunity in mice, whether addition of Hia to Hap augments protective immunity in mice, and whether sequential immunization with protein and mRNA stimulates an enhanced immune response against Hap, HMW1/HMW2, and Hia and produces increased protection in mice.

Role: PI

Past support since 2000

Research Agreement (St. Geme and Barenkamp, PI’s)              1/1/97-12/31/00

Connaught Laboratories

Vaccine potential of the Haemophilus influenzae HMW1/HMW2 and Hia adhesins

The major goal of this project was to define domains of the HMW and Hia proteins that are immunogenic and stimulate protective immunity.

9640107N (St. Geme, PI)                            01/01/97-12/31/01

American Heart Association

“Molecular characterization of a novel H. influenzae serine protease”

The major goals of this project were to characterize the influence of Hap on Haemophilus interactions with human respiratory epithelium and to define the mechanism by which lactoferrin inhibits Hap activity.

#1-FY99-284 (St. Geme, PI)                            06/01/99-05/31/02

March of Dimes

“Molecular analysis of the Haemophilus influenzae adherence and penetration protein”

The major goal of this project was to characterize Hap autoproteolysis and protease activity.

Research Agreement (St. Geme, PI)                            06/27/96-12/31/02

Wyeth-Lederle Vaccines

“Vaccine potential of the Haemophilus influenzae Hap protein”

The major goal of this project was to define domains of Hap that are immunogenic and stimulate protective immunity.

1 R01 AI49322 (St. Geme, PI)                            09/15/02-12/31/08             

NIH/NIAID                           

“Haemophilus Hap-mediated microcolony formation”

The major goals of this project were to characterize the relationship between respiratory viral infection and Hap-mediated microcolony formation and to examine the ability of microcolonies to resist host immune mechanisms.

R01 AI44167 (St. Geme, PI)                            12/15/98-04/30/10             

NIH/NIAID                           

“Biology of the H. influenzae Hia and Hsf adhesins”

The major goals of this project were to elucidate the relationship between structure and function in the Hia and Hsf passenger domains and outer membrane translocator domains, and to elucidate the interaction between Hia and Hsf and host epithelial cells.

Supplement (St. Geme, PI)                            07/17/09-06/30/11             

NIH/NIDCD                           

“Biology of the HMW1 and HMW2 adhesins of Haemophilus influenzae”

The major goals of this project were to define the structural determinants of HMW1C binding of UDP-hexose molecules.

6-FY08-2008 (St. Geme, PI)                            06/01/08-05/31/11             

March of Dimes

“Virulence determinants of the Haemophilus Crytpic Genospecies”

The major goal of this grant was to characterize the molecular determinants of the interaction between the Haemophilus cryptic genospecies Cha adhesin and host epithelial cells.

1UL1 RR024128 (Califf, PI)                                                                      10/01/06-06/30/11                           

NIH/NCRR

Duke CTSI

The focus of the Duke Clinical and Translational Sciences Institute (Duke CTSI) was to reorganize the Duke research enterprise, building on those elements that are world class and focusing new funding on novel structures that have been identified as critical to overcoming barriers to success in this new environment.

1T32 HD43029-04 (St. Geme, PI)                            07/01/02-07/30/12                        

NIH/NICHD                                                                   (PI – 7/1/05)

“Duke Research Training Program for Pediatricians”

The major goal of this program relates to the lack of understanding of the processes underlying pediatric illnesses, resulting in a heavy burden on the health of children and their families.  Our program is addressing this issue by selecting pediatric subspecialty fellows with promise as investigators and placing these individuals in mentored research environments to develop skills in either laboratory investigation or clinical research.

5K12 HD43494 (St. Geme, PI)                            04/11/03-11/30/17                      

NIH/NICHD                            (PI – 7/1/05)

Center for Molecular & Cellular Studies of Pediatric Disease

The major goals of this program are to improve our understanding of the processes underlying pediatric disease and to develop more effective approaches to treatment and prevention of childhood illness.  In order to achieve these goals, we are training and mentoring young investigators who are junior faculty members in the Department of Pediatrics.  These individuals devote at least 75% of their time to research. 

U54 AI057157 (Sparling, PI)                            3/15/09 - 02/28/14             

NIH-NIAID                                                                                   

Prime award              UNC-Chapel Hill                           

Southeast Regional Center of Excellence in Bioterrorism and Emerging Infections

PI, Duke University Administrative Core

(St. Geme, PI) 1R56 AI103125-01                                                                                    09/13/13-9/12/15

NIH-NIAID                                                       

“Molecular basis of virulence in the emerging pathogen Kingella kingae”

The major goal of this project is to identify the genetic determinants of the biosynthesis and export of the Kingella kingae polysaccharide capsule.

(St. Geme, PI) R01 DC02873                            06/01/95-02/28/16             

NIH/NIDCD                           

“Biology of the HMW1 and HMW2 adhesins of Haemophilus influenzae”

The major goals of this project were to elucidate the molecular details of HMW1 and HMW2 glycosylation, processing, secretion, and adhesive activity.

Patents:

U.S. Patent No. 5,869,065 "High molecular weight surface proteins of non-typeable Haemophilus"

U.S. Patent No. 8,296,791 "Haemophilus influenzae Adherence and Penetration Protein"

U.S. Patent No. 6,200,57 "Haemophilus adhesion proteins"

Clinical Activity:

Washington University (1992-2005)

Pediatric Infectious Diseases Attending, St. Louis Children's Hospital, inpatient consultation service 1-1 1/2 months/year, clinic 1 day/week

General Pediatrics Attending, St. Louis Children's Hospital, 1 month/year

Pediatric Infectious Diseases Consultant, St. Louis Shriners' Hospital for Crippled Children, Missouri Baptist Medical Center

Duke University Medical Center (2005-2013)

Pediatric Infectious Diseases Attending, Duke University Hospital

General Pediatrics Attending, Duke University Hospital

The Children’s Hospital of Philadelphia (2013-present)

Pediatric Infectious Diseases Attending

General Pediatrics Attending