Matthew M. Laughon, MD, MPH
Disclosures: Nothing to disclose - 05/25/2022
SUGGESTED CATEGORIES FOR

                           

Matthew M. Laughon, MD, MPH

Curriculum Vitae

 

 

Personal information

                           

Business Address:             

CB# 7596, 4th Floor, UNC Hospitals

Chapel Hill, NC  27599-7596

Phone: (984) 974-7851

Mobile: (919) 824-6373

Email: matt_laughon@med.unc.edu

 

 

Education

 

2004                            MPH, Epidemiology

The University of North Carolina at Chapel Hill

School of Public Health

Chapel Hill, NC

 

2001-2004             Neonatal-Perinatal Medicine Subspecialty Residency (Fellowship)

The University of North Carolina at Chapel Hill

Chapel Hill, NC

 

1998-2001              Pediatrics Internship/Residency

The University of North Carolina at Chapel Hill

Chapel Hill, NC

 

1998                            Doctor of Medicine

University of Virginia School of Medicine

Charlottesville, VA

 

1994                            Bachelor of Science, magna cum laude

Major: Biology

Davidson College

Davidson, NC

 

Certification/Licensure:

1999-present              North Carolina State Board of Medical Examiners license #82490

2006, 2015               Neonatal/Perinatal Medicine: Board Certified

2001                            Pediatrics: Board Certified

 

Professional Experience -- Employment History 

 

2015-present              Professor, with Tenure

The University of North Carolina at Chapel Hill

Department of Pediatrics

Division of Neonatal-Perinatal Medicine

Chapel Hill, NC

 

2010-2015              Associate Professor, with Tenure

The University of North Carolina at Chapel Hill

Department of Pediatrics

Division of Neonatal-Perinatal Medicine

Chapel Hill, NC

 

2004-2010              Assistant Professor

The University of North Carolina at Chapel Hill

Department of Pediatrics

Division of Neonatal-Perinatal Medicine

Chapel Hill, NC

 

2004-present              Clinical Affiliate

Department of Medicine

Pediatrics-Neonatology

Moore Regional Hospital

Pinehurst, NC

 

Honors

 

2003-2004              K30 Scholar-Clinical Research Curriculum: NIH institutional grant program designed to aid individuals interested in clinical research in development of research ideas and grant writing,

1990-1994              Samuel H. Bell honor scholar, Davidson College

1993                            Phi Beta Kappa

 

Bibliography

 

* Note: First author a trainee: Faculty Member, Subspecialty Resident (Fellow), Resident, or Medical Student.

 

Books and Chapters

 

  1. Jain L and Suresh GK, editors. Clinical Guidelines in Neonatology. Laughon M, Section Editor Cardiovascular Disorders, Section 5. 2019. pp 305-333.
  2. England A*, Hill K, and Laughon M. Management of PDA in premature infants after discharge, Malcolm W, editor. 2014. Chapter 9.  pp 88-103.
  3. Aliaga S* and Laughon M.  The risks and benefits of management strategies of the patent ductus arteriosus in preterm infants. Invited book chapter, “Controversies around treatment of the open duct”. Poets C, editor. 2011.  pp 115-127.
  4. Moya F and Laughon M. Common Problems of the Newborn. Editors Reece EA, Hobbins JC, Gant Jr NF. Handbook of Clinical Obstetrics: the Fetus & Mother. Blackwell Publishing Ltd. 2008. 526-539.

 

Refereed Papers/Articles

Original Research

1.                  Blakely ML, Tyson JE, Lally KP, Hintz SR, Eggleston B, Stevenson DK, Besner GE, Das A, Ohls RK, Truog WE, Nelin LD, Poindexter BB, Pedroza C, Walsh MC, Stoll BJ, Geller R, Kennedy KA, Dimmitt RA, Carlo WA, Cotten CM, Laptook AR, Van Meurs KP, Calkins KL, Sokol GM, Sanchez PJ, Wyckoff MH, Patel RM, Frantz ID 3rd, Shankaran S, D'Angio CT, Yoder BA, Bell EF, Watterberg KL, Martin CA, Harmon CM, Rice H, Kurkchubasche AG, Sylvester K, Dunn JCY, Markel TA, Diesen DL, Bhatia AM, Flake A, Chwals WJ, Brown R, Bass KD, St Peter SD, Shanti CM, Pegoli W Jr, Skarda D, Shilyansky J, Lemon DG, Mosquera RA, Peralta-Carcelen M, Goldstein RF, Vohr BR, Purdy IB, Hines AC, Maitre NL, Heyne RJ, DeMauro SB, McGowan EC, Yolton K, Kilbride HW, Natarajan G, Yost K, Winter S, Colaizy TT, Laughon MM, Lakshminrusimha S, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health, Human Development Neonatal Research Network. Initial Laparotomy Versus Peritoneal Drainage in Extremely Low Birthweight Infants With Surgical Necrotizing Enterocolitis or Isolated Intestinal Perforation: A Multicenter Randomized Clinical Trial. Ann Surg. 2021 Oct 1;274(4):e370-e380.

2.                  Stark A, Smith PB, Hornik CP, Zimmerman KO, Hornik CD, Pradeep S, Clark RH, Benjamin DK Jr, Laughon M, Greenberg RG. Medication Use in the Neonatal Intensive Care Unit and Changes from 2010 to 2018. J Pediatr. 2021 Sep 2:S0022-3476(21)00860-X.

3.                  Lane MD*, Kishnani S, Udemadu O, Danquah SE, Treadway RM 3rd, Langman A, Balevic S, Jackson WM, Laughon M, Hornik CP, Greenberg RG, Clark RH, Zimmerman KO. Comparative efficacy and safety of late surfactant preparations: a retrospective study. J Perinatol. 2021 Jul 20:1-6.

4.                  Baud O, Laughon M, Lehert P. Survival without Bronchopulmonary Dysplasia of Extremely Preterm Infants: A Predictive Model at Birth. Neonatology. 2021 May.

5.                     Rysavy MA*, Li L, Tyson JE, Jensen EA, Das A, Ambalavanan N, Laughon MM, Greenberg RG, Patel RM, Pedroza C, Bell EF; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Should Vitamin A Injections to Prevent Bronchopulmonary Dysplasia or Death Be Reserved for High-Risk Infants?: Reanalysis of the NICHD Neonatal Research Network Randomized Trial. J Pediatr. 2021 May 15:S0022-3476(21)00445-5.

6.                     Miller LE*, Laughon MM, Clark RH, Zimmerman KO, Hornik CP, Aleem S, Brian Smith P, Greenberg RG. Vasoactive medications in extremely low gestational age neonates during the first postnatal week. J Perinatol. 2021 Mar 23.

7.                     Bamat NA*, Nelin TD, Eichenwald EC, Kirpalani H, Laughon MM, Jackson WM, Jensen EA, Gibbs KA, Lorch SA. Loop Diuretics in Severe Bronchopulmonary Dysplasia: Cumulative Use and Associations with Mortality and Age at Discharge. J Pediatr. 2021 Apr;231:43-49.e3.

8.                     Schneider S*, Bailey M, Spears T, Esther CR Jr, Laughon MM, Hornik CP, Jackson W. Safety of sildenafil in premature infants with severe bronchopulmonary dysplasia (SILDI-SAFE): a multicenter, randomized, placebo-controlled, sequential dose-escalating, double-masked, safety study. BMC Pediatr. 2020 Dec 14;20(1):559.

9.                  Dorismond C*, Hunter SE, McNaull PP, Zimmerman KO, Benjamin DK, Greenberg RG, Corey KM, Laughon MM, Jackson WM. Wide range of perioperative drugs and doses used in inguinal hernia repairs for premature infants. J Perinatol. 2020 Oct 23.

10.              Green CA*, Westreich D, Laughon MM, Stamilio DM, Strauss RA, Reese J, Shelton EL, Venkatesh KK. Association of chorioamnionitis and patent ductus arteriosus in a national U.S. cohort. J Perinatol. 2020 Oct 22.

11.              Thompson EJ*, Benjamin DK, Greenberg RG, Kumar KR, Zimmerman KO, Laughon M, Clark RH, Smith PB, Hornik CP. Pharmacoepidemiology of Furosemide in the Neonatal Intensive Care Unit. Neonatology. 2020 Oct 7:1-5.

12.              Salerno SN*, Liao Y, Jackson W, Greenberg RG, McKinzie CJ, McCallister A, Benjamin DK, Laughon MM, Sanderson K, Clark RH, Gonzalez D. Association between Nephrotoxic Drug Combinations and Acute Kidney Injury in the Neonatal Intensive Care Unit. J Pediatr. 2020 Aug 17

13.              Clark RH, Sousa J, Laughon MM, Tolia VN. Gastroschisis prevalence substantially decreased from 2009 through 2018 after a 3-fold increase from 1997 to 2008. J Pediatr Surg. 2020 Mar 24.

14.              Jackson W*, Taylor G, Bamat NA, Zimmerman K, Clark R, Benjamin DK, Laughon MM, Greenberg RG, Hornik CP.  Outcomes associated with surfactant in more mature and larger premature infants with respiratory distress syndrome. J Perinatol. 2020 Feb 20.

15.              Ji D, Smith PB, Clark RH, Zimmerman KO, Laughon M, Ku L, Greenberg RG. Wide variation in caffeine discontinuation timing in premature infants. J Perinatol. 2020 Feb;40(2):288-293.

16.              Zimmerman KO*, Wu H, Laughon M, Greenberg RG, Walczak R, Schulman SR, Smith PB, Hornik CP, Cohen-Wolkowiez M, Watt KM. Dexmedetomidine Pharmacokinetics and a New Dosing Paradigm in Infants Supported With Cardiopulmonary Bypass.  Anesth Analg. 2019 Dec;129(6):1519-1528.

17.              Thébaud B, Goss KN, Laughon M, Whitsett JA, Abman SH, Steinhorn RH, Aschner JL, Davis PG, McGrath-Morrow SA, Soll RF, Jobe AH. Bronchopulmonary dysplasia. Nat Rev Dis Primers. 2019 Nov 14;5(1):78.

18.              Thompson EJ*, Wu H, Melloni C, Balevic S, Sullivan JE, Laughon M, Clark KM, Kalra R, Mendley S, Payne EH, Erinjeri J, Gelber CE, Harper B, Cohen-Wolkowiez M, Hornik CP; Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee. Population Pharmacokinetics of Doxycycline in Children. Antimicrob Agents Chemother. 2019 Sep 23.

19.              Gonski S*, Hupp SR, Cotten CM, Clark RH, Laughon M, Watt K, Hornik CP, Kumar K, Smith PB, Greenberg RG. Risk of development of treated retinopathy of prematurity in very low birth weight infants. J Perinatol. 2019 Sep 6

20.              Gonzalez D*, Laughon MM, Smith PB, Ge S, Ambalavanan N, Atz A, Sokol GM, Hornik CD, Stewart D, Mundakel G, Poindexter BB, Gaedigk R, Mills M, Cohen-Wolkowiez M, Martz K, Hornik CP; Best Pharmaceuticals for Children Act - Pediatric Trials Network Steering Committee. Population Pharmacokinetics of Sildenafil in Extremely Premature Infants. Br J Clin Pharmacol. 2019 Sep 2.

 

21.              Bamat NA, Kirpalani H, Feudtner C, Jensen EA, Laughon MM, Zhang H, Monk HM, Passarella M, Lorch SA. Medication use in infants with severe bronchopulmonary dysplasia admitted to United States children's hospitals. J Perinatol. 2019 Jun 21.

22.              Puia-Dumitrescu M*, Smith PB, Zhao J, Soriano A, Payne EH, Harper B, Bendel-Stenzel E, Moya F, Chhabra R, Ku L, Laughon M, Wade KC; Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committee. Dosing and Safety of Off-label Use of Caffeine Citrate in Premature Infants. J Pediatr. J Pediatr. 2019 Aug;211:27-32.e1.

23.              Jensen EA, Dysart K, Gantz MG, McDonald S, Bamat NA, Keszler M, Kirpalani H, Laughon MM, Poindexter BB, Duncan AF, Yoder BA, Eichenwald E, DeMauro SB; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. The Diagnosis of Bronchopulmonary Dysplasia in Very Preterm Infants: An Evidence-Based Approach. Am J Respir Crit Care Med. 2019 Sep 15;200(6):751-759

24.              Hornik CP, Atz AM, Bendel C, Chan F, Downes K, Grundmeier R, Fogel B, Gipson D, Laughon M, Miller M, Smith M, Livingston C, Kluchar C, Heath A, Jarrett C, McKerlie B, Patel H, Hunter C; Best Pharmaceuticals for Children Act–Pediatric Trials Network. Creation of a Multicenter Pediatric Inpatient Data Repository Derived from Electronic Health Records. Appl Clin Inform. 2019 Mar;10(2):307-315.

25.              Smith PB, Cotten CM, Hudak ML, Sullivan JE, Poindexter BB, Cohen-Wolkowiez M, Boakye-Agyeman F, Lewandowski A, Anand R, Benjamin DK Jr, Laughon MM; Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee. Rifampin Pharmacokinetics and Safety in Preterm and Term Infants. Antimicrob Agents Chemother. 2019 May 24;63(6)

26.              Venkatesh KK*, Jackson W, Hughes BL, Laughon MM, Thorp JM, Stamilio DM. Association of chorioamnionitis and its duration with neonatal morbidity and mortality. J Perinatol. 2019 Feb 5.

27.              Watt KM, Hornik CP, Balevic SJ, Mundakel G, Cotten CM, Harper B, Benjamin DK, Anand R, Laughon M, Smith PB, Cohen-Wolkowiez M; Best Pharmaceuticals for Children Act - Pediatric Trials Network Steering Committee. Pharmacokinetics of ticarcillin-clavulanate in premature infants. Br J Clin Pharmacol. 2019 Feb 2.

28.              Taylor G*, Jackson W, Hornik CP, Koss A, Mantena S, Homsley K, Gattis B, Kudumu-Clavell M, Clark R, Smith PB, Laughon MM. Surfactant Administration in Preterm Infants: Drug Development Opportunities.J Pediatr. 2018 Dec 21.

29.              Tolia VN, Bahr TM, Bennett MM, Martin G, Greenberg RG, Laughon MM, Clark RH. The Association of Hydrocortisone Dosage on Mortality in Infants Born Extremely Premature. J Pediatr. 2018 Dec 21.

30.              Greenberg RG, Gayam S, Savage D, Tong A, Gorham D, Sholomon A, Clark RH, Benjamin DK, Laughon M, Smith PB; Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee. Furosemide Exposure and Prevention of Bronchopulmonary Dysplasia in Premature Infants. J Pediatr. 2018 Dec 20.

31.              Jackson W*, Taylor G, Selewski D, Smith PB, Tolleson-Rinehart S, Laughon MM. Association between furosemide in premature infants and sensorineural hearing loss and nephrocalcinosis: a systematic review. Matern Health Neonatol Perinatol. 2018 Nov 19;4:23.

32.              McCrary AW*, Barker PCA, Torok RD, Spears TG, Li JS, Hornik CP, Laughon MM.  Agreement of an echocardiogram-based diagnosis of pulmonary hypertension in infants at risk for bronchopulmonary dysplasia among masked reviewers. J Perinatol. 2019 Feb;39(2):248-255.

33.              Hanvey IB*, Aliaga S, Laughon MM, Testoni D, Smith PB, Bauserman M. Trial Characteristics That Affect Parental Consent in Neonatal Drug Trials. Am J Perinatol. 2018 Oct 31.

34.              Phelps DL, Watterberg KL, Nolen TL, Cole CA, Cotten CM, Oh W, Poindexter BB, Zaterka-Baxter KM, Das A, Lacy CB, Scorsone AM, Walsh MC, Bell EF, Kennedy KA, Schibler K, Sokol GM, Laughon MM, Lakshminrusimha S, Truog WE, Garg M, Carlo WA, Laptook AR, Van Meurs KP, Carlton DP, Graf A, DeMauro SB, Brion LP, Shankaran S, Orge FH, Olson RJ, Mintz-Hittner H, Yang MB, Haider KM, Wallace DK, Chung M, Hug D, Tsui I, Cogen MS, Donahue JP, Gaynon M, Hutchinson AK, Bremer DL, Quinn G, He YG, Lucas WR Jr, Winter TW, Kicklighter SD, Kumar K, Chess PR, Colaizy TT, Hibbs AM, Ambalavanan N, Harmon HM, McGowan EC, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Effects of Myo-inositol on Type 1 Retinopathy of Prematurity Among Preterm Infants <28 Weeks' Gestational Age: A Randomized Clinical Trial. JAMA. 2018 Oct 23;320(16):1649-1658.

35.              Wang LA*, Smith PB, Laughon M, Goldberg RN, Ku LC, Zimmerman KO, Balevic S, Clark RH, Benjamin DK, Greenberg RG; Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee. Prolonged furosemide exposure and risk of abnormal newborn hearing screen in premature infants. Early Hum Dev. 2018 Oct;125:26-30.

36.              Kumar KR*, Clark DA, Kim EM, Perry JD, Wright K, Thomas SA, Thompson EJ, Greenberg RG, Smith PB, Benjamin DK Jr, Laughon MM, Clark RH, Hornik CP. Association of Atrial Septal Defects and Bronchopulmonary Dysplasia in Premature Infants. J Pediatr. 2018 Aug 29.

37.              Jackson WM*, O'Shea TM, Allred EN, Laughon MM, Gower WA, Leviton A. Risk factors for chronic lung disease and asthma differ among children born extremely preterm. Pediatr Pulmonol. 2018 Nov;53(11):1533-1540.

38.              Zimmerman KO*, Wu H, Laughon M, Greenberg RG, Walczak R, Schulman SR, Smith PB, Hornik CP, Cohen-Wolkowiez M, Watt KM. Dexmedetomidine Pharmacokinetics and a New Dosing Paradigm in Infants Supported With Cardiopulmonary Bypass. Anesth Analg. 2018 Aug 22.

39.              Thompson EJ*, Perez K, Hornik CP, Smith PB, Clark RH, Laughon M; Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee. Sildenafil Exposure in the Neonatal Intensive Care Unit.Am J Perinatol. 2018 Aug 6.

40.              Ge S, Beechinor RJ, Hornik CP, Standing JF, Zimmerman K, Cohen-Wolkowiez M, Laughon MM, Clark R, Gonzalez D. External Evaluation of a Gentamicin Infant Population Pharmacokinetic Model Using Data from a National Electronic Health Record Database. Antimicrob Agents Chemother. 2018 Jun 18.

41.              Heling AZ*, Laughon MM, Price WA. Effect of Routine, Screening Head Ultrasounds on Clinical Interventions for Premature Infants.  Am J Perinatol. 2018 Aug;35(10):959-963.

42.              Thompson EJ*, Greenberg RG, Kumar K, Laughon M, Smith PB, Clark RH, Crowell A, Shaw L, Harrison L, Scales G, Bell N, Hornik CP. Association between Furosemide Exposure and Patent Ductus Arteriosus in Hospitalized Infants of Very Low Birth Weight. J Pediatr. 2018 Aug;199:231-236.

43.              Dallefeld SH*, Atz AM, Yogev R, Sullivan JE, Al-Uzri A, Mendley SR, Laughon M, Hornik CP, Melloni C, Harper B, Lewandowski A, Mitchell J, Wu H, Green TP, Cohen-Wolkowiez M. A pharmacokinetic model for amiodarone in infants developed from an opportunistic sampling trial and published literature data. J Pharmacokinet Pharmacodyn. 2018 Jun;45(3):419-430.

44.              Le J, Poindexter B, Sullivan JE, Laughon M, Delmore P, Blackford M, Yogev R, James LP, Melloni C, Harper B, Mitchell J, Benjamin DK Jr, Boakye-Agyeman F, Cohen-Wolkowiez M. Comparative Analysis of Ampicillin Plasma and Dried Blood Spot Pharmacokinetics in Neonates. Ther Drug Monit. 2018 Feb;40(1):103-108.

45.              Hornik CP, Onufrak NJ, Smith PB, Cohen-Wolkowiez M, Laughon MM, Clark RH, Gonzalez D. Association between oral sildenafil dosing, predicted exposure, and systemic hypotension in hospitalised infants. Cardiol Young. 2018 Jan;28(1):85-92.

46.              Steinhorn R, Davis JM, Göpel W, Jobe A, Abman S, Laughon M, Bancalari E, Aschner J, Ballard R, Greenough A, Storari L, Thomson M, Ariagno RL, Fabbri L, Turner MA; International Neonatal Consortium. Chronic Pulmonary Insufficiency of Prematurity: Developing Optimal Endpoints for Drug Development. J Pediatr. 2017 Dec;191:15-21.e1.

47.              Schueller M, Greenberg RG, Smith PB, Laughon MM, Clark RH, Hornik CP. In-Hospital Outcomes Following Extracorporeal Membrane Oxygenation in a Retrospective Cohort of Infants. Am J Perinatol. 2017 Nov;34(13):1347-1353.

48.              Thompson EJ*, Greenberg RG, Kumar K, Laughon M, Smith PB, Clark RH, Crowell A, Shaw L, Harrison L, Scales G, Bell N, Hornik CP. Association between Furosemide Exposure and Patent Ductus Arteriosus in Hospitalized Infants of Very Low Birth Weight. J Pediatr. 2018 May 8.

49.              Salerno SN*, Bernhardt J, Laughon M, Jhaveri R, Massaro M, Gonzalez D. Pharmacokinetics of Ceftaroline in a Preterm Infant With Methicillin-Resistant Staphylococcus Aureus Pneumonia. J Pediatric Infect Dis Soc. 2017 Oct 16.

50.              Lee JH, Greenberg RG, Quek BH, Clark RH, Laughon MM, Smith PB, Hornik CP. Association between early echocardiography, therapy for patent ductus arteriosus, and outcomes in very low birth weight infants. Cardiol Young. 2017 Nov;27(9):1732-1739.

51.              Shah M, Phillips MR, Klein M, Marzinsky A, Rice C, Laughon M, Lee S. A Single Institution Study of Umbilical Vein Complications and Necrotizing Enterocolitis in Premature Infants. Am Surg. 2017 Sep 1;83(9):364-366.

52.              Jensen EA*, Dysart KC, Gantz MG, Carper B, Higgins RD, Keszler M, Laughon MM, Poindexter BB, Stoll BJ, Walsh MC, Schmidt B; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.. Association between Use of Prophylactic Indomethacin and the Risk for Bronchopulmonary Dysplasia in Extremely Preterm Infants. J Pediatr. 2017 July; 34-40.

53.              Jackson W*, Hornik CP, Messina JA, Guglielmo K, Watwe A, Delancy G, Valdez A, MacArthur T, Peter-Wohl S, Smith PB, Tolia VN, Laughon MM. In-hospital outcomes of premature infants with severe bronchopulmonary dysplasia. J Perinatol. 2017 July; 37(7):853-856.

54.              Downey LC*, Cotten CM, Hornik CP, Laughon MM, Tolia VN, Clark RH, Smith PB. Association of in utero magnesium exposure and spontaneous intestinal perforations in extremely low birth weight infants. J Perinatol. 2017 Jan 26.

55.              Schueller M, Greenberg RG, Smith PB, Laughon MM, Clark RH, Hornik CP. In-Hospital Outcomes Following Extracorporeal Membrane Oxygenation in a Retrospective Cohort of Infants. Am J Perinatol. 2017 May 25.

56.              Greenberg RG*, Wu H, Laughon M, Capparelli E, Rowe S, Zimmerman KO, Smith PB, Cohen-Wolkowiez M. Population Pharmacokinetics of Dexmedetomidine in Infants. J Clin Pharmacol. 2017 Apr 25.

57.              Hornik CP, Onufrak NJ, Smith PB, Cohen-Wolkowiez M, Laughon MM, Clark RH, Gonzalez D. Association between oral sildenafil dosing, predicted exposure, and systemic hypotension in hospitalised infants. Cardiol Young. 2017 Aug 8:1-8.

58.              Virkud YV*, Hornik CP, Benjamin DK, Laughon MM, Clark RH, Greenberg RG, Smith PB. Respiratory Support for Very Low Birth Weight Infants Receiving Dexamethasone. J Pediatr. 2017 Jan 18.

59.              Lemyre B, Laughon M, Bose C, Davis PG.  Early nasal intermittent positive pressure ventilation (NIPPV) versus early nasal continuous positive airway pressure (NCPAP) for preterm infants. Cochrane Database Syst Rev. 2016 Dec 15.

60.              Zimmerman KO*, Smith PB, Benjamin DK, Laughon M, Clark R, Traube C, Stürmer T, Hornik CP. Sedation, Analgesia, and Paralysis during Mechanical Ventilation of Premature Infants. J Pediatr. 2017 Jan;180:99-104.

61.              Allman R, Sousa J, Walker MW, Laughon MM, Spitzer AR, Clark RH. The epidemiology, prevalence and hospital outcomes of infants with gastroschisis. J Perinatol. 2016 Oct;36(10):901-5.

62.              Thakkar N*, Gonzalez D, Cohen-Wolkowiez M, Massaro MM, Bernhardt J, Zane NR, Laughon MM. An opportunistic study evaluating pharmacokinetics of sildenafil for the treatment of pulmonary hypertension in infants. J Perinatol. 2016 Sep;36(9):744-7.

63.              Momper JD, Capparelli EV, Wade KC, Kantak A, Dhanireddy R, Cummings JJ, Nedrelow JH, Hudak ML, Mundakel GT, Natarajan G, Gao J, Laughon M, Smith PB, Benjamin DK Jr. Population Pharmacokinetics of Fluconazole in Premature Infants with Birth Weights Less than 750 Grams. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5539-45.

64.              Zimmerman KO*, Smith PB, Benjamin DK, Laughon M, Clark R, Traube C, Stürmer T, Hornik CP. Sedation, Analgesia, and Paralysis during Mechanical Ventilation of Premature Infants. J Pediatr. 2016 Aug 10.

65.              Aliaga S, Zhang J, Long DL, Herring AH, Laughon M, Boggess K, Reddy UM, Grantz KL. Center Variation in the Delivery of Indicated Late Preterm Births. Am J Perinatol. 2016 Apr 27.

66.              Hornik CP, Sherwood AL, Cotten CM, Laughon MM, Clark RH, Smith PB. Daily mortality of infants born at less than 30 weeks' gestation. Early Hum Dev. 2016 May;96:27-30.

67.              England A*, Wade K, Smith PB, Berezny K, Laughon M; Best Pharmaceuticals for Children Act — Pediatric Trials Network Administrative Core Committee. Optimizing operational efficiencies in early phase trials: The Pediatric Trials Network experience. Contemp Clin Trials. 2016 Mar;47:376-82.

68.              Lee JH, Smith PB, Quek MB, Laughon MM, Clark RH, Hornik CP. Risk Factors and In-Hospital Outcomes following Tracheostomy in Infants. J Pediatr. 2016 Jun;173:39-44.e1

69.              Gonzalez D*, Delmore P, Bloom BT, Cotten CM, Poindexter BB, McGowan E, Shattuck K, Bradford KK, Smith PB, Cohen-Wolkowiez M, Morris M, Yin W, Benjamin DK Jr, Laughon MM. Clindamycin Pharmacokinetics and Safety in Preterm and Term Infants. Antimicrob Agents Chemother. 2016 Apr 22;60(5):2888-94.

70.              Gulack BC*, Laughon MM, Clark RH, Burgess T, Robinson S, Muhammad A, Zhang A, Davis A, Morton R, Chu VH, Arnold CJ, Hornik CP, Smith PB. Enteral Feeding with Human Milk Decreases Time to Discharge in Infants following Gastroschisis Repair. J Pediatr. 2015 Dec 15.

71.              Kelly MS*, Benjamin DK, Puopolo KM, Laughon MM, Clark RH, Mukhopadhyay S, Benjamin DK Jr, Smith PB, Permar SR. Postnatal Cytomegalovirus Infection and the Risk for Bronchopulmonary Dysplasia. JAMA Pediatr. 2015 Dec 7;169 (12):e153785.

72.              Askenazi DJ, Morgan C, Goldstein SL, Selewski DT, Moxey-Mims MM, Kimmel PL, Star RA, Higgins R, Laughon M Strategies to improve the understanding of long-term renal consequences after neonatal acute kidney injury. Pediatr Res. 2015 Nov 23.

73.              Greenberg RG*, Cochran KM, Smith PB, Edson BS, Schulman J, Lee HC, Govindaswami B, Pantoja A, Hardy D, Curran J, Lin D, Kuo S, Noguchi A, Ittmann P, Duncan S, Gupta M, Picarillo A, Karna P, Cohen M, Giuliano M, Carroll S, Page B, Guzman-Cottrill J, Walker MW, Garland J, Ancona JK, Ellsbury DL, Laughon MM, McCaffrey MJ. Effect of Catheter Dwell Time on Risk of Central Line-Associated Bloodstream Infection in Infants. Pediatrics. 2015 Dec;136 (6):1080-6.

74.              Batton B, Li L, Newman NS, Das A, Watterberg KL, Yoder BA, Faix RG, Laughon MM, Stoll BJ, Higgins RD, Walsh MC; Eunice Kennedy Shriver National Institute of Child Health & Human Development Neonatal Research Network. Early blood pressure, antihypotensive therapy and outcomes at 18-22 months' corrected age in extremely preterm infants. Arch Dis Child Fetal Neonatal Ed. 2015 Nov 13.

75.              Samiee-Zafarghandy S, van den Anker JN, Laughon MM, Clark RH, Smith PB, Hornik CP. Sildenafil and retinopathy of prematurity risk in very low birth weight infants. J Perinatol. 2016 Feb;36(2):137-40.

76.              Lee JH*, Hornik CP, Testoni D, Laughon MM, Cotten CM, Maldonado RS, Belcastro MR, Clark RH, Smith PB. Insulin, Hyperglycemia, and Severe Retinopathy of Prematurity in Extremely Low-Birth-Weight Infants. Am J Perinatol. 2015 Oct 20.

77.              Gulack BC*, Laughon MM, Clark RH, Sankar MN, Hornik CP, Brian Smith P. Comparative effectiveness and safety of indomethacin versus ibuprofen for the treatment of patent ductus arteriosus. Early Hum Dev. 2015 Dec;91(12):725-9.

78.              Pineda LC, Hornik CP, Seed PC, Cotten CM, Laughon MM, Bidegain M, Clark RH, Smith PB. Association between positive urine cultures and necrotizing enterocolitis in a large cohort of hospitalized infants. Early Hum Dev. 2015 Jul 27;91 (10):583-586.

79.              Zimmerman KO*, Hornik CP, Ku L, Watt K, Laughon MM, Bidegain M, Clark RH, Smith PB. Sedatives and Analgesics Given to Infants in Neonatal Intensive Care Units at the End of Life. J Pediatr. 2015 Aug;167 (2):299-304.e3.

80.              Malowitz JR*, Hornik CP, Laughon MM, Testoni D, Cotten CM, Clark RH, Smith PB. Management Practice and Mortality for Infants with Congenital Diaphragmatic Hernia. Am J Perinatol. 2015 Feb 25.

81.              Autmizguine J*, Hornik CP, Benjamin DK Jr, Laughon MM, Clark RH, Cotten CM, Cohen-Wolkowiez M, Benjamin DK, Smith PB; Best Pharmaceuticals for Children Act—Pediatric Trials Network Administrative Core Committee. Anaerobic antimicrobial therapy after necrotizing enterocolitis in VLBW infants.Pediatrics. 2015 Jan;135 (1):e117-25.

82.              Price WA, Aliaga SR, Massie SE, DeWalt DA, Laughon MM, Malcolm WF, Van Meurs K, Klein JM, El-Ferzli G, Magnus BE, Tolleson-Rinehart S. Development and Validation of the Proxy-Reported Pulmonary Outcomes Scale for Premature Infants. Am J Perinatol. 2015 Feb 25.

83.              Shankaran S, Laptook AR, Pappas A, McDonald SA, Das A, Tyson JE, Poindexter BB, Schibler K, Bell EF, Heyne RJ, Pedroza C, Bara R, Van Meurs KP, Grisby C, Huitema CM, Garg M, Ehrenkranz RA, Shepherd EG, Chalak LF, Hamrick SE, Khan AM, Reynolds AM, Laughon MM, Truog WE, Dysart KC, Carlo WA, Walsh MC, Watterberg KL, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Effect of depth and duration of cooling on deaths in the NICU among neonates with hypoxic ischemic encephalopathy: a randomized clinical trial. JAMA. 2014 Dec 24-31;312 (24):2629-39.

84.              Ambalavanan N, Carlo WA, Wrage LA, Das A, Laughon M, Cotten CM, Kennedy KA, Laptook AR, Shankaran S, Walsh MC, Higgins RD; For the SUPPORT Study Group of the NICHD Neonatal Research Network. PaCO2 in Surfactant, Positive Pressure, and Oxygenation Randomised Trial (SUPPORT). Arch Dis Child Fetal Neonatal Ed. 2014 Nov 25.

85.              Dasnadi S*, Aliaga S, Laughon M, Warner DD, Price WA. Factors Influencing the Accuracy of Noninvasive Blood Pressure Measurements in NICU Infants. Am J Perinatol. 2014 Oct 26.

86.              Beam KS*, Aliaga S, Ahlfeld SK, Cohen-Wolkowiez M, Smith PB, Laughon MM. A systematic review of randomized controlled trials for the prevention of bronchopulmonary dysplasia in infants. J Perinatol. 2014 Sep;34(9):705-10.

87.              Sriram S, Condie J, Schreiber MD, Batton DG, Shah B, Bose C, Laughon M, Van Marter LJ, Allred EN, Leviton A. Early blood gas predictors of bronchopulmonary dysplasia in extremely low gestational age newborns. Int J Pediatr. 2014;2014:210218.

88.              Corey KM*, Hornik CP, Laughon MM, McHutchison K, Clark RH, Smith PB. Frequency of anomalies and hospital outcomes in infants with gastroschisis and omphalocele. Early Hum Dev. 2014 Aug;90(8):421-4. Laughon MM, Chantala K, Aliaga S, Herring AH, Hornik CP, Hughes R, Clark RH, Smith PB. Diuretic Exposure in Premature Infants from 1997 to 2011. Am J Perinatol. 2014 May 6.

89.              Beam KS*, Laughon MM, Hornik CP, Cohen-Wolkowiez M, Clark RH, Benjamin DK Jr, Smith PB. Predictors of positive cerebrospinal fluid cultures in infants with bacteremia. Pediatr Infect Dis J. 2014 Apr;33(4):360-5.

90.              Tremoulet A, Le J, Poindexter B, Sullivan JE, Laughon M, Delmore P, Salgado A, Ian-U Chong S, Melloni C, Gao J, Benjamin DK Jr, Capparelli EV, Cohen-Wolkowiez M; on behalf of the Administrative Core Committee of the Best Pharmaceuticals for Children Act-Pediatric Trials Network. Characterization of the Population Pharmacokinetics of Ampicillin in Neonates Using an Opportunistic Study Design. Antimicrob Agents Chemother. 2014 Jun;58(6):3013-3020.

91.              Batton B, Li L, Newman NS, Das A, Watterberg KL, Yoder BA, Faix RG, Laughon MM, Stoll BJ, Higgins RD, Walsh MC; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Evolving blood pressure dynamics for extremely preterm infants. J Perinatol. 2014 Apr;34(4):301-5.

92.              Dobson NR, Patel RM*, Smith PB, Kuehn DR, Clark J, Vyas-Read S, Herring A, Laughon MM, Carlton D, Hunt CE. Trends in Caffeine Use and Association between Clinical Outcomes and Timing of Therapy in Very Low Birth Weight Infants. J Pediatr. 2014 May;164(5):992-998.e3.

93.              Aliaga S*, Clark RH, Laughon M, Walsh TJ, Hope WW, Benjamin DK, Kaufman D, Arrieta A, Benjamin DK Jr, Smith PB. Changes in the incidence of candidiasis in neonatal intensive care units. Pediatrics. 2014 Feb;133(2):236-42.

94.              Hsieh EM*, Hornik CP, Clark RH, Laughon MM, Benjamin DK Jr, Smith PB; on Behalf of the Best Pharmaceuticals for Children Act—Pediatric Trials Network. Medication Use in the Neonatal Intensive Care Unit. Am J Perinatol. 2013 Dec 17.

95.              Onland W, Debray TP, Laughon MM, Miedema M, Cools F, Askie LM, Asselin JM, Calvert SA, Courtney SE, Dani C, Durand DJ, Marlow N, Peacock JL, Pillow JJ, Soll RF, Thome UH, Truffert P, Schreiber MD, Van Reempts P, Vendettuoli V, Vento G, van Kaam AH, Moons KG, Offringa M. Clinical prediction models for bronchopulmonary dysplasia: a systematic review and external validation study. BMC Pediatr. 2013 Dec 17;13:207.

96.              Laughon MM, Avant D, Tripathi N, Hornik CP, Cohen-Wolkowiez M, Clark RH, Smith PB, Rodriguez W. Drug labeling and exposure in neonates.  JAMA Pediatr. 2014 Feb;168 (2):130-6.

97.              Tunks RD, Barker PC, Benjamin DK Jr, Cohen-Wolkowiez M, Fleming GA, Laughon M, Li JS, Hill KD. Sildenafil Exposure and Hemodynamic Effect After Fontan Surgery. Pediatr Crit Care Med. 2013 Nov 6.

98.              Hill KD*, Tunks RD, Barker PC, Benjamin DK Jr, Cohen-Wolkowiez M, Fleming GA, Laughon M, Li JS. Sildenafil exposure and hemodynamic effect after stage II single-ventricle surgery. Pediatr Crit Care Med. 2013 Jul;14 (6):593-600.

99.              Trembath A*, Hornik CP, Clark R, Smith PB, Daniels J, Laughon M; Best Pharmaceuticals for Children Act—Pediatric Trials Network. Comparative effectiveness of surfactant preparations in premature infants. J Pediatr. 2013 Oct;163 (4):955-60.e1.

100.          Alleman BW, Bell EF, Li L, Dagle JM, Smith PB, Ambalavanan N, Laughon MM, Stoll BJ, Goldberg RN, Carlo WA, Murray JC, Cotten CM, Shankaran S, Walsh MC, Laptook AR, Ellsbury DL, Hale EC, Newman NS, Wallace DD, Das A, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Individual and center-level factors affecting mortality among extremely low birth weight infants. Pediatrics. 2013 Jul;132 (1):e175-84.

101.          Batton B, Li L, Newman NS, Das A, Watterberg KL, Yoder BA, Faix RG, Laughon MM, Stoll BJ, Van Meurs KP, Carlo WA, Poindexter BB, Bell EF, Sánchez PJ, Ehrenkranz RA, Goldberg RN, Laptook AR, Kennedy KA, Frantz ID 3rd, Shankaran S, Schibler K, Higgins RD, Walsh MC; Eunice Kennedy Shriver National Institute of Child Health & Human Development Neonatal Research Network. Use of antihypotensive therapies in extremely preterm infants. Pediatrics. 2013 Jun;131(6):e1865-73.

102.          Bose CL, Laughon MM, Allred EN, O'Shea TM, Van Marter LJ, Ehrenkranz RA, Fichorova RN, Leviton A; ELGAN Study Investigators. Systemic inflammation associated with mechanical ventilation among extremely preterm infants. Cytokine. 2013 Jan;61(1):315-22.

103.          Aliaga SR*, Smith PB, Price WA, Ivester TS, Boggess K, Tolleson-Rinehart S, McCaffrey MJ, Laughon MM. Regional variation in late preterm births in North Carolina. Matern Child Health J. 2013 Jan;17(1):33-41.

104.          Bauserman MS*, Laughon MM, Hornik CP, Smith PB, Benjamin DK Jr, Clark RH, Engmann C, Cohen-Wolkowiez M. Group B Streptococcus and Escherichia coli Infections in the Intensive Care Nursery in the Era of Intrapartum Antibiotic Prophylaxis. Pediatr Infect Dis J. 2012 Sep 24.

105.          Cohen-Wolkowiez M, Poindexter B, Bidegain M, Weitkamp JH, Schelonka RL, Randolph DA, Ward RM, Wade K, Valencia G, Burchfield D, Arrieta A, Mehta V, Walsh M, Kantak A, Rasmussen M, Sullivan JE, Finer N, Rich W, Brozanski BS, van den Anker J, Blumer J, Laughon M, Watt KM, Kearns GL, Capparelli EV, Martz K, Berezny K, Benjamin DK Jr, Smith PB; Meropenem Study Team. Safety and effectiveness of meropenem in infants with suspected or complicated intra-abdominal infections. Clin Infect Dis. 2012 Dec;55(11):1495-502. Downey LC*, Benjamin DK Jr, Clark RH, Watt KM, Hornik CP, Laughon MM, Cohen-Wolkowiez M, Smith PB. Urinary tract infection concordance with positive blood and cerebrospinal fluid cultures in the neonatal intensive care unit. J Perinatol. 2012 Aug 30.

106.          Downey LC*, Benjamin DK Jr, Clark RH, Watt KM, Hornik CP, Laughon MM, Cohen-Wolkowiez M, Smith PB. Urinary tract infection concordance with positive blood and cerebrospinal fluid cultures in the neonatal intensive care unit. J Perinatol. 2012 Aug 30. PMCID: 3549035.

107.          Turner K*, Manzoni P, Benjamin DK, Cohen-Wolkowiez M, Smith PB, Laughon MM. Fluconazole pharmacokinetics and safety in premature infants. Curr Med Chem. 2012;19(27):4617-20.

108.          Smith PB, Ambalavanan N, Li L, Cotten CM, Laughon M, Walsh MC, Das A, Bell EF, Carlo WA, Stoll BJ, Shankaran S, Laptook AR, Higgins RD, Goldberg RN; Generic Database Subcommittee; Eunice Kennedy Shriver National Institute of Child Health Human Development Neonatal Research Network. Approach to infants born at 22 to 24 weeks' gestation: relationship to outcomes of more-mature infants. Pediatrics. 2012 Jun;129(6):e1508-16.

109.          Batton BJ, Li L, Newman NS, Das A, Watterberg KL, Yoder BA, Faix RG, Laughon MM, Van Meurs KP, Carlo WA, Higgins RD, Walsh MC; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Feasibility study of early blood pressure management in extremely preterm infants. J Pediatr. 2012 Jul;161(1):65-9.e1.

110.          Watt KM*, Massaro MM, Smith B, Cohen-Wolkowiez M, Benjamin DK Jr, Laughon MM. Pharmacokinetics of Moxifloxacin in an Infant With Mycoplasma hominis Meningitis. Pediatr Infect Dis J. 2011 Oct 19.

111.          Laughon MM, Benjamin DK Jr, Capparelli EV, Kearns GL, Berezny K, Paul IM, Wade K, Barrett J, Smith PB, Cohen-Wolkowiez M. Innovative clinical trial design for pediatric therapeutics. Expert Rev Clin Pharmacol. 2011 Sep;4(5):643-652.

112.          Massie SE, Tolleson-Rinehart S, DeWalt DA, Laughon MM, Powell LM, Price WA. Development of a proxy-reported pulmonary outcome scale for preterm infants with bronchopulmonary dysplasia. Health Qual Life Outcomes. 2011 Jul 26;9:55.

113.          Jean-Baptiste N*, Benjamin DK Jr, Cohen-Wolkowiez M, Fowler VG Jr, Laughon M, Clark RH, Smith PB. Coagulase-negative staphylococcal infections in the neonatal intensive care unit. Infect Control Hosp Epidemiol. 2011 Jul;32(7):679-86.

114.          Laughon M, Bose C, Allred EN, O’Shea TM, Ehrenkranz RA, Van Marter LJ, Leviton A; for the ELGAN Study Investigators. Patterns of blood protein concentrations of ELGANs classified by three patterns of respiratory disease in the first two postnatal weeks. Pediatr Res. 2011 Jun 3. PMCID: PMC309030.

115.          Clark RH, Gordon P, Walker WM, Laughon M, Smith PB, Spitzer AR. Characteristics of patients who die of necrotizing enterocolitis. J Perinatol. 2011 May 19.

116.          Laughon MM, Langer JC, Bose CL, Smith PB, Ambalavanan N, Kennedy KA, Stoll BJ, Buchter S, Laptook AR, Ehrenkranz RA, Cotten CM, Wilson-Costello DE, Shankaran S, Van Meurs KP, Davis AS, Gantz MG, Finer NN, Yoder BA, Faix RG, Carlo WA, Schibler KR, Newman NS, Rich W, Das A, Higgins RD, Walsh MC; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Prediction of bronchopulmonary dysplasia by postnatal age in extremely premature infants. Am J Respir Crit Care Med. 2011 Jun 15;183(12):1715-22. PMCID pending

116.1.1.1.   NOTE: an electronic, free version of the NICHD Neonatal Research Network bronchopulmonary dysplasia estimator is available at https://neonatal.rti.org/index.cfm?fuseaction=BPDCalculator.start; this has been accessed >50,000 times

117.          Laughon M, Bose C, Allred EN, O'Shea TM, Ehrenkranz RA, Van Marter LJ, Leviton A; for the ELGAN Study Investigators. Antecedents of chronic lung disease following three patterns of early respiratory disease in preterm infants. Arch Dis Child Fetal Neonatal Ed. 2011 Mar;96(2):F114-F120.

118.          Van Marter LJ, Kuban KC, Allred E, Bose C, Dammann O, O'Shea M, Laughon M, Ehrenkranz RA, Schreiber MD, Karna P, Leviton A; ELGAN Study Investigators. Does bronchopulmonary dysplasia contribute to the occurrence of cerebral palsy among infants born before 28 weeks of gestation? Arch Dis Child Fetal Neonatal Ed. 2011 Jan;96(1):F20-9.

119.          Logan JW*, O'Shea TM, Allred EN, Laughon MM, Bose CL, Dammann O, Batton DG, Kuban KC, Paneth N, Leviton A. Early postnatal hypotension is not associated with indicators of white matter damage or cerebral palsy in extremely low gestational age newborns. J Perinatol. 2011 Jan 27.

120.          Greenberg RG, Benjamin DK Jr, Cohen-Wolkowiez M, Clark RH, Cotten CM, Laughon M, Smith PB. Repeat lumbar punctures in infants with meningitis in the neonatal intensive care unit. J Perinatol. 2010 Dec 16.

121.          Courtwright AM*, Laughon MM, Doron MW. Length of life and treatment intensity in infants diagnosed prenatally or postnatally with congenital anomalies considered to be lethal. J Perinatol. 2010 Dec 16.

122.          Bose C, Laughon M, Allred EN, Van Marter LJ, Oʼshea TM, Ehrenkranz RA, Fichorova R, Leviton A; for the ELGAN Study Investigators. Blood protein concentrations in the first two postnatal weeks that predict bronchopulmonary dysplasia among infants born before the 28th week of gestation. Pediatr Res. 2010 Dec 9.

123.          Logan JW, O'Shea TM, Allred EN, Laughon MM, Bose CL, Dammann O, Batton DG, Engelke SC, Leviton A; for the ELGAN Study Investigators. Early postnatal hypotension and developmental delay at 24 months of age among extremely low gestational age newborns. Arch Dis Child Fetal Neonatal Ed. 2010 Dec 7.

124.          Laughon M, Smith PB, Bose C. Prevention of Chronic Lung Disease. Archives of Diseases in Childhood: Neonatal-Perinatal Edition Dec;14(6):374-82. Epub 2009 Sep 6.

125.          Bose C, Van Marter LJ, Laughon M, O’Shea M, Allred EN, Karna P, Ehrenkranz RA, Boggess K, Leviton A. Fetal growth restriction is followed by an increased risk of chronic lung disease among infants born before the 28th week of gestation. Pediatrics. 2009 Aug 17.

126.          Laughon M, O’Shea TM, Allred EN, Bose C, Kuban K, Van Marter LJ, Ehrenkranz RA, Leviton A. Chronic lung disease and the risk of developmental delay at two years of age in children without severe gross motor delays born before 28 weeks postmenstrual age. Pediatrics. 2009 Jul 20.

127.          Troy R*, Doron M, Laughon M, Tolleson-Rinehart S, Price W. Comparison of Non-Invasive and Central Arterial Blood Pressure Measurements in Extremely Low Birth Weight Infants. Journal of Perinatology, 2009 Nov;29(11):744-9.

128.          Laughon M, Allred EN, Bose C, O'Shea TM, Van Marter LJ, Ehrenkranz RA, Leviton A. Patterns of respiratory disease during the first 2 postnatal weeks in extremely premature infants. Pediatrics. 2009 Apr;123(4):1124-31.

129.          Laughon M, Bose C, Moya F, Aschner J, Donn SM, Morabito C, Cummings JJ, Segal R, Guardia C, Liu G. A pilot randomized, controlled trial of later treatment with a Peptide-containing, synthetic surfactant for the prevention of bronchopulmonary dysplasia. Pediatrics. 2009 Jan;123(1):89-96.

130.          Rojas MA, Lozano JM, Rojas MX, Laughon M, Bose CL, Rondon MA, Charry L, Bastidas JA, Perez LA, Rojas C, Ovalle O, Celis LA, Garcia-Harker J, Jaramillo ML. Very early surfactant without mandatory ventilation in premature infants treated with early continuous positive airway pressure: a randomized, controlled trial. Pediatrics. 2009 Jan;123(1):137-42.

131.          South AP*, Marshall DD, Bose CL, Laughon M. Growth and neurodevelopment at 16 to 24 months of age for infants born with gastroschisis. J Perinatol. 2008 Jul 10.

132.          Herrman K*, Bose C, Lewis K, Laughon M. Spontaneous Closure of the Patent Ductus Arteriosus in Very Low Birth Weight Infants Following Discharge from the Neonatal Unit. Arch Dis Ch. 2008 May 1.

133.          Laughon M, Bose C, Allred E, O'Shea TM, Van Marter LJ, Bednarek F, Leviton A. Factors associated with treatment for hypotension in extremely low gestational age newborns during the first postnatal week. Pediatrics. 2007 Feb;119(2):273-80.

134.          Laughon M, Bose C, Clark R. Treatment strategies to prevent or close a patent ductus arteriosus in preterm infants and outcomes. J Perinatol. 2007 Mar;27(3):164-70.

135.          Raval MV*, Laughon M, Bose CL, Phillips JD. Patent ductus arteriosus ligation in premature infants: who really benefits, and at what cost? J Pediatr Surg. 2007 Jan;42(1):69-75; discussion.

136.          Eng W*, LeGrys VA, Schechter MS, Laughon M, Barker PM. Sweat-testing in preterm and full-term infants less than 6 weeks of age. Pediatr Pulmonol. 2005 Jul;40(1):64-7.

137.          Laughon M, Meyer R, Bose C, Wall A, Otero E, Heerens A, Clark R. Rising birth prevalence of gastroschisis. J Perinatol. 2003 Jun;23(4):291-3.

138.          Mohr JJ, Randolph GD, Laughon M, Schaff E. Integrating improvement competencies into residency education: a pilot project from a pediatric continuity clinic. Ambul Pediatr. 2003 May-Jun;3(3):131-6.

139.          Faulkner DM, Sutton ST, Hesford JD, Faulkner BC, Major DA, Hellewell TB, Laughon M, Rodeheaver GT, Edlich RF. A new stable pluronic F68 gel carrier for antibiotics in contaminated wound treatment. Am J Emerg Med. 1997 Jan;15(1):20-4.

140.          Zemmel NJ, Park SM, Schweitzer J, O'Keefe JS, Laughon M, Edlich RF. Status of Voicetype Dictation for Windows for the emergency physician. J Emerg Med. 1996 Jul-Aug;14(4):511-5.

141.          Gerard MW, Laughon M, Colley JL, 3rd, Glasheen WP, Hoard MA, Edlich RF. Trends in temporomandibular joint surgery. Med Prog Technol. 1996;21(4):171-5.

 

Other Peer Reviewed Articles

  1. Steinhorn R, Davis JM, Göpel W, Jobe A, Abman S, Laughon M, Bancalari E, Aschner J, Ballard R, Greenough A, Storari L, Thomson M, Ariagno RL, Fabbri L, Turner MA; International Neonatal Consortium. Chronic Pulmonary Insufficiency of Prematurity: Developing Optimal Endpoints for Drug Development.J Pediatr. 2017 Dec;191:15-21.e1.
  2. Johnson JK*, Laughon MM. Antimicrobial Agent Dosing in Infants. Clin Ther. 2016 Sep;38(9):1948-60.
  3. Perez KM*, Laughon M. Sildenafil in Term and Premature Infants: A Systematic Review. Clin Ther. 2015 Nov 1;37(11):2598-2607.e1.
  4. Ericson JE*, Laughon MM. Chorioamnionitis: Implications for the Neonate. Clin Perinatol. 2015 Mar;42(1):155-165.
  5. Perez KM*, Laughon MM. What is new for patent ductus arteriosus management in premature infants in 2015? Curr Opin Pediatr. 2015 Feb 13.
  6. Smith PB, Laughon MM. Dissemination of Information from Pediatric Studies Conducted under BPCA and PREA. National Academies of Science Institute of Medicine, Appendix B 2013.
  7. Trembath A*, Laughon MM. Predictors of bronchopulmonary dysplasia. Clin Perinatol. 2012 Sep;39(3):585-601. doi: 10.1016/j.clp.2012.06.014.
  8. Laughon M, Bose C, Benitz WE. Patent ductus arteriosus management: what are the next steps? J Pediatr. 2010 Sep;157(3):355-7. Epub 2010 Jun 30.
  9. Bose CL, Laughon M, Dammann CE. Bronchopulmonary dysplasia and inflammatory biomarkers in the premature neonate. Arch Dis Child Fetal Neonatal Ed. 2008;93(6):F455-61.
  10. Bose CL, Laughon M. Patent ductus arteriosus: lack of evidence for common treatments. Arch Dis Child Fetal Neonatal Ed. 2007 Nov;92(6):F498-502.
  11. Bose CL, Laughon M. Treatment to prevent patency of the ductus arteriosus: beneficial or harmful? J Pediatr. 2006 Jun;148(6):713-4.
  12. Laughon M, Simmons MA, Bose CL. Patency of the ductus arteriosus in the premature infant: is it pathologic? Should it be treated? Curr Opin Pediatr. 2004 Apr;16(2):146-51.

 

Invited Editorials

1.                  Simmons MA, Laughon MM. 50 Years Ago in The Journal of Pediatrics: A Practical Classification of Newborn Infants by Weight and Gestational Age. J Pediatr. 2017 Aug;187:33.

2.                  Reese J, Laughon MM. The Patent Ductus Arteriosus Problem: Infants Who Still Need Treatment. J Pediatr. 2015 Nov;167(5):954-6.

3.                  Laughon MM. Vitamin a shortage and risk of bronchopulmonary dysplasia. JAMA Pediatr. 2014 Nov 1;168(11):995-6.

4.                  Laughon MM, Benjamin DK Jr. Mechanisms to provide safe and effective drugs for children. 2014. Pediatrics;134(2):e562-3.

5.                  Knight DB, Laughon M. Evidence for active closure of patent ductus arteriosus in very preterm infants. J Pediatr. 2008 Mar;152(3):446-7; author reply 7-8.

6.                  Bose CL, Laughon M. Corticosteroids and chronic lung disease: time for another randomized, controlled trial? Pediatrics. 2005 Mar;115(3):794.

Listed in Acknowledgements

  1. Maharaj AR, Wu H, Zimmerman KO, Muller WJ, Sullivan JE, Sherwin CMT, Autmizguine J, Rathore MH, Hornik CD, Al-Uzri A, Payne EH, Benjamin DK Jr, Hornik CP; Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee. Pharmacokinetics of Ceftazidime in Children and Adolescents with Obesity. Paediatr Drugs. 2021.
  2. Ganguly S, Edginton AN, Gerhart JG, Cohen-Wolkowiez M, Greenberg RG, Gonzalez D; Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee. Physiologically Based Pharmacokinetic Modeling of Meropenem in Preterm and Term Infants. Clin Pharmacokinet. 2021.
  3. Le J, Greenberg RG, Benjamin DK, Yoo Y, Zimmerman KO, Cohen-Wolkowiez M, Wade KC; Administrative Core Committee of the Best Pharmaceuticals for Children Act–Pediatric Trials Network. Prolonged Post-Discontinuation Antibiotic Exposure in Very Low Birth Weight Neonates at Risk for Early-Onset Sepsis. J Pediatric Infect Dis Soc. 2021 May 28;10(5):615-621.
  4. Kumbhat N, Eggleston B, Davis AS, DeMauro SB, Van Meurs KP, Foglia EE, Lakshminrusimha S, Walsh MC, Watterberg KL, Wyckoff MH, Das A, Handley SC; Generic Database Subcommittee of the National Institute of Child Health and Human Development Neonatal Research Network. Umbilical Cord Milking vs Delayed Cord Clamping and Associations with In-Hospital Outcomes among Extremely Premature Infants. J Pediatr. 2021 May;232:87-94.e4.
  5. Kirpalani H, Bell EF, Hintz SR, Tan S, Schmidt B, Chaudhary AS, Johnson KJ, Crawford MM, Newman JE, Vohr BR, Carlo WA, D'Angio CT, Kennedy KA, Ohls RK, Poindexter BB, Schibler K, Whyte RK, Widness JA, Zupancic JAF, Wyckoff MH, Truog WE, Walsh MC, Chock VY, Laptook AR, Sokol GM, Yoder BA, Patel RM, Cotten CM, Carmen MF, Devaskar U, Chawla S, Seabrook R, Higgins RD, Das A; Eunice Kennedy Shriver NICHD Neonatal Research Network. Higher or Lower Hemoglobin Transfusion Thresholds for Preterm Infants. N Engl J Med. 2020 Dec 31;383(27):2639-2651.
  6. Laptook AR, Shankaran S, Barnes P, Rollins N, Do BT, Parikh NA, Hamrick S, Hintz SR, Tyson JE, Bell EF, Ambalavanan N, Goldberg RN, Pappas A, Huitema C, Pedroza C, Chaudhary AS, Hensman AM, Das A, Wyckoff M, Khan A, Walsh MC, Watterberg KL, Faix R, Truog W, Guillet R, Sokol GM, Poindexter BB, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Limitations of Conventional Magnetic Resonance Imaging as a Predictor of Death or Disability Following Neonatal Hypoxic-Ischemic Encephalopathy in the Late Hypothermia Trial. J Pediatr. 2021 Mar;230:106-111.e6.
  7. Dworetz AR, Natarajan G, Langer J, Kinlaw K, James JR, Bidegain M, Das A, Poindexter B, Bell EF, Cotten CM, Kirpalani H, Shankaran S, Stoll BJ; Eunice Kennedy Shriver National Institute of Child Health; Human Development Neonatal Research Network. Arch Dis Child Fetal Neonatal Ed. 2020 Oct 20:fetalneonatal-2020-318855.Harmon HM, Jensen EA, Tan S, Chaudhary AS, Slaughter JL, Bell EF, Wyckoff MH, Hensman AM, Sokol GM, DeMauro SB. Withholding or withdrawing life-sustaining treatment in extremely low gestational age neonates; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Timing of postnatal steroids for bronchopulmonary dysplasia: association with pulmonary and neurodevelopmental outcomes.  J Perinatol. 2020 Apr;40(4):616-627.
  8. Brumbaugh JE, Bell EF, Grey SF, DeMauro SB, Vohr BR, Harmon HM, Bann CM, Rysavy MA, Logan JW, Colaizy TT, Peralta-Carcelen MA, McGowan EC, Duncan AF, Stoll BJ, Das A, Hintz SR; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Behavior Profiles at 2 Years for Children Born Extremely Preterm with Bronchopulmonary Dysplasia. J Pediatr. 2020 Apr;219:152-159.e5
  9. Shenoi RP, Timm N; COMMITTEE ON DRUGS; COMMITTEE ON PEDIATRIC EMERGENCY MEDICINE. Drugs Used to Treat Pediatric Emergencies.  Pediatrics. 2020 Jan;145(1).
  10. Shankaran S, Bell EF, Laptook AR, Saha S, Newman NS, Kazzi SNJ, Barks J, Stoll BJ, Bara R, Gabrio J, Childs K, Das A, Higgins RD, Carlo WA, Sánchez PJ, Carlton DP, Pavageau L, Malcolm WF, D'Angio CT, Ohls RK, Poindexter BB, Sokol GM, Van Meurs KP, Colaizy TT, Khmour A, Puopolo KM, Garg M, Walsh MC; Eunice Kennedy Shriver National Institute of Child Health, and Human Development Neonatal Research Network. Weaning of Moderately Preterm Infants from the Incubator to the Crib: A Randomized Clinical Trial. J Pediatr. 2018 Oct 15.
  11. Shakhnovich V, Brian Smith P, Guptill JT, James LP, Collier DN, Wu H, Livingston CE, Zhao J, Kearns GL, Cohen-Wolkowiez M; Best Pharmaceuticals for Children Act–Pediatric Trials Network. A Population-Based Pharmacokinetic Model Approach to Pantoprazole Dosing for Obese Children and Adolescents. Paediatr Drugs. 2018 Oct;20(5):483-495.
  12. Shakhnovich V, Smith PB, Guptill JT, James LP, Collier DN, Wu H, Livingston CE, Zhao J, Kearns GL; Best Pharmaceuticals for Children Act – Pediatric Trials Network. Obese Children Require Lower Doses of Pantoprazole Than Nonobese Peers to Achieve Equal Systemic Drug Exposures. J Pediatr. 2018 Feb;193:102-108.e1
  13. Sarkar S, Shankaran S, Barks J, Do BT, Laptook AR, Das A, Ambalavanan N, Van Meurs KP, Bell EF, Sanchez PJ, Hintz SR, Wyckoff MH, Stoll BJ, Carlo WA; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Outcome of Preterm Infants with Transient Cystic Periventricular Leukomalacia on Serial Cranial Imaging Up to Term Equivalent Age. J Pediatr. 2018 Apr;195:59-65.e3
  14. Natarajan G, Shankaran S, Saha S, Laptook A, Das A, Higgins R, Stoll BJ, Bell EF, Carlo WA, D'Angio C, DeMauro SB, Sanchez P, Van Meurs K, Vohr B, Newman N, Hale E, Walsh M; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Antecedents and Outcomes of Abnormal Cranial Imaging in Moderately Preterm Infants. J Pediatr. 2018 Apr;195:66-72.e3
  15. Bajaj M, Natarajan G, Shankaran S, Wyckoff M, Laptook AR, Bell EF, Stoll BJ, Carlo WA, Vohr BR, Saha S, Van Meurs KP, Sanchez PJ, D'Angio CT, Higgins RD, Das A, Newman N, Walsh MC; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Delivery Room Resuscitation and Short-Term Outcomes in Moderately Preterm Infants.J Pediatr. 2018 Apr;195:33-38.e2.
  16. Laptook AR, Bell EF, Shankaran S, Boghossian NS, Wyckoff MH, Kandefer S, Walsh M, Saha S, Higgins R; Generic and Moderate Preterm Subcommittees of the NICHD Neonatal Research Network. Admission Temperature and Associated Mortality and Morbidity among Moderately and Extremely Preterm Infants.J Pediatr. 2018 Jan;192:53-59.e2.
  17. James J, Munson D, DeMauro SB, Langer JC, Dworetz AR, Natarajan G, Bidegain M, Fortney CA, Seabrook R, Vohr BR, Tyson JE, Bell EF, Poindexter BB, Shankaran S, Higgins RD, Das A, Stoll BJ, Kirpalani H; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Outcomes of Preterm Infants following Discussions about Withdrawal or Withholding of Life Support. J Pediatr. 2017 Jun 21.
  18. Younge N, Goldstein RF, Bann CM, Hintz SR, Patel RM, Smith PB, Bell EF, Rysavy MA, Duncan AF, Vohr BR, Das A, Goldberg RN, Higgins RD, Cotten CM; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Survival and Neurodevelopmental Outcomes among Periviable Infants. N Engl J Med. 2017 Feb 16;376(7):617-628.
  19. Gonzalez D, Chamberlain JM, Guptill JT, Cohen-Wolkowiez M, Harper B, Zhao J, Capparelli EV; Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee. Population Pharmacokinetics and Exploratory Pharmacodynamics of Lorazepam in Pediatric Status Epilepticus. Clin Pharmacokinet. 2016 Dec 9.
  20. Ku LC, Zimmerman K, Benjamin DK, Clark RH, Hornik CP, Smith PB; Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee. Safety of Enalapril in Infants Admitted to the Neonatal Intensive Care Unit. Pediatr Cardiol. 2016 Nov 8.
  21. Ericson JE, Kaufman DA, Kicklighter SD, Bhatia J, Testoni D, Gao J, Smith PB, Prather KO, Benjamin DK Jr; Fluconazole Prophylaxis Study Team on behalf of the Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee. Fluconazole Prophylaxis for the Prevention of Candidiasis in Premature Infants: A Meta-analysis Using Patient-level Data. Clin Infect Dis. 2016 Sep 1;63(5):604-10.
  22. Harskamp-van Ginkel MW, Hill KD, Becker K, Testoni D, Cohen-Wolkowiez M, Gonzalez D, Barrett JS, Benjamin DK Jr, Siegel DA, Banks P, Watt KM; Best Pharmaceuticals for Children Act–Pediatric Trials Network Administrative Core Committee. Drug Dosing and Pharmacokinetics in Children With Obesity: A Systematic Review. JAMA Pediatr. 2015 Jul;169(7):678-85.
  23. Trachtman H, Frymoyer A, Lewandowski A, Greenbaum LA, Feig DI, Gipson DS, Warady BA, Goebel JW, Schwartz GJ, Lewis K, Anand R, Patel UD; Best Pharmaceuticals for Children Act-Pediatric Trials Network Administrative Core Committee. Pharmacokinetics, Pharmacodynamics, and Safety of Lisinopril in Pediatric Kidney Transplant Patients: Implications for Starting Dose Selection. Clin Pharmacol Ther. 2015 Jul;98(1):25-33.
  24. Gonzalez D, Melloni C, Poindexter BB, Yogev R, Atz AM, Sullivan JE, Mendley SR, Delmore P, Delinsky A, Zimmerman K, Lewandowski A, Harper B, Lewis KC, Benjamin DK Jr, Cohen-Wolkowiez M; Best Pharmaceuticals for Children Act--Pediatric Trials Network Administrative Core Committee. Simultaneous determination of trimethoprim and sulfamethoxazole in dried plasma and urine spots. Bioanalysis. 2015;7(9):1137-49.
  25. Testoni D, Hornik CP, Neely ML, Yang Q, McMahon AW, Clark RH, Smith PB; Best Pharmaceuticals for Children Act — Pediatric Trials Network Administrative Core Committee. Safety of octreotide in hospitalized infants. Early Hum Dev. 2015 Jul;91(7):387-92.
  26. Ericson JE, Arnold C, Cheeseman J, Cho J, Kaneko S, Wilson E, Clark RH, Benjamin DK Jr, Chu V, Smith PB, Hornik CP; Best Pharmaceuticals for Children Act–Pediatric Trials Network Administrative Core Committee. Use and Safety of Erythromycin and Metoclopramide in Hospitalized Infants. J Pediatr Gastroenterol Nutr. 2015 Sep;61(3):334-9.
  27. Hoffman L, Bann C, Higgins R, Vohr B; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Developmental outcomes of extremely preterm infants born to adolescent mothers. Pediatrics. 2015 Jun;135(6):1082-92.
  28. Samiee-Zafarghandy S, Raman SR, van den Anker JN, McHutchison K, Hornik CP, Clark RH, Brian Smith P; Best Pharmaceuticals for Children Act—Pediatric Trials Network Administrative Core Committee. Safety of milrinone use in neonatal intensive care units. Early Hum Dev. 2015 Jan;91(1):31-5.
  29. De Jesus LC, Sood BG, Shankaran S, Kendrick D, Das A, Bell EF, Stoll BJ, Laptook AR, Walsh MC, Carlo WA, Sanchez PJ, Van Meurs KP, Bara R, Hale EC, Newman NS, Ball MB, Higgins RD; Eunice Kennedy Shriver National Institute of Health and Human Development Neonatal Research Network. Antenatal magnesium sulfate exposure and acute cardiorespiratory events in preterm infants. Am J Obstet Gynecol. 2015 Jan;212(1):94.e1-7.
  30. Shankaran S, Lin A, Maller-Kesselman J, Zhang H, O'Shea TM, Bada HS, Kaiser JR, Lifton RP, Bauer CR, Ment LR; Gene Targets for Intraventricular Hemorrhage Study. Maternal race, demography, and health care disparities impact risk for intraventricular hemorrhage in preterm neonates. J Pediatr. 2014 May;164(5):1005-1011.e3.
  31. Adén U, Lin A, Carlo W, Leviton A, Murray JC, Hallman M, Lifton RP, Zhang H, Ment LR; Gene Targets for Intraventricular Hemorrhage Study Group. Candidate gene analysis: severe intraventricular hemorrhage in inborn preterm neonates. J Pediatr. 2013 Nov;163(5):1503-6.e1.
  32. Sampson MR, Bloom BT, Lenfestey RW, Harper B, Kashuba AD, Anand R, Benjamin DK Jr, Capparelli E, Cohen-Wolkowiez M, Smith PB; Best Pharmaceuticals for Children Act–Pediatric Trials Network. Population pharmacokinetics of intravenous acyclovir in preterm and term infants. Pediatr Infect Dis J. 2014 Jan;33(1):42-9
  33. Adén U, Lin A, Carlo W, Leviton A, Murray JC, Hallman M, Lifton RP, Zhang H, Ment LR; Gene Targets for Intraventricular Hemorrhage Study Group. Candidate gene analysis: severe intraventricular hemorrhage in inborn preterm neonates. J Pediatr. 2013 Nov;163(5):1503-6.e1
  34. Abdel-Rahman SM, Paul IM, James LP, Lewandowski A; Best Pharmaceuticals for Children Act-Pediatric Trials Network. Evaluation of the Mercy TAPE: performance against the standard for pediatric weight estimation. Ann Emerg Med. 2013 Oct;62(4):332-339.e6
  35. Cohen-Wolkowiez M, Sampson M, Bloom BT, Arrieta A, Wynn JL, Martz K, Harper B, Kearns GL, Capparelli EV, Siegel D, Benjamin DK Jr, Smith PB; Best Pharmaceuticals for Children Act–Pediatric Trials Network. Determining population and developmental pharmacokinetics of metronidazole using plasma and dried blood spot samples from premature infants.  Pediatr Infect Dis J. 2013 Sep;32(9):956-61.
  36. Wu JM, Viswanathan M, Ivy JS; North Carolina Research Collaborative on Mode of Delivery (NCRC-MOD). A conceptual framework for future research on mode of delivery. Matern Child Health J. 2012 Oct;16(7):1447-54.

Abstracts (Note: PAS no longer publishes abstracts from 2017 forward; mean ~6/year)

  1. Wang L, Clark R, Smith PB. Laughon M, Ku L, Greenberg R.  Long-Term Furosemide Exposure and Abnormal Hearing Screen in Premature Infants. 4151.403.               PAS 2016.
  2. Greenberg R, Wu H, Laughon M, Capparelli E, Benjamin, Jr DK, Smith PB, Cohen-Wolkowiez M. Population Pharmacokinetics (PK) of Dexmedetomidine in Infants. 4630.5. PAS 2016.
  3. England M*, Greenberg R, Clark R, Laughon M, Cohen-Wolkowiez M, Benjamin, Jr D, Smith PB.  Dosing of Antimicrobials in the Neonatal Intensive Care Unit: Does Clinical Practice Reflect Published Recommendations? 2720A.4. PAS 2016.
  4. Jensen E*, Dysart K, Gantz M, Higgins R, Kendrick D, Keszler M, Laughon M, Poindexter B, Stoll B, Walsh M, Schmidt B. Prophylactic Indomethacin Is Not Associated with a Reduced Risk of BPD in Extremely Preterm Infants. 2780.1. PAS 2015.
  5. Momper J*, Capparelli EV, Wade KC, Natarajan G, Gao J, Laughon M, Smith PB, Benjamin Jr DK. Population Pharmacokinetics of Fluconazole in Extremely Low Birth Weight Infants. 2790.1. PAS 2015.
  6. Zimmerman KO*, Smith PB, Benjamin DK, Laughon M, Clark R, Hornik, CP. Increased Use of Sedatives and Analgesics During Mechanical Ventilation of Premature Infants. PAS 2015. 2924.578.              
  7. Gipson D, Kirkendall E, Gumbs B, Quinn T, Herreshoff E, Jones C, Laughon M, Nicholas S, Thomas S, Zajicek A, Haber M, Stephen Hirschfeld. Development of International Pediatric Adverse Event Terminology. 4168.511. PAS 2015.
  8. Hanvey I*, Aliaga S, Bauserman M, Smith PB, Laughon M.  Parental Consent in Neonatal Drug Trials. 4192.684. PAS 2015.
  9. Hupp S*, Greenberg R, Cotten M, Clark R, Laughon M, Hornik C, Watt K, Smith PB. Risk of Development of Severe Retinopathy of Prematurity in Very Low Birth Weight Infants. Publication 3848.790. PAS 2014.
  10. Zimmerman KO*, Hornik CP, Watt KM, Clark RH, Laughon MM, Smith PB. Sedatives and Analgesics Given To Dying Infants in Neonatal Intensive Care Units Publication.2385.2. PAS 2014.
  11. Gostelow M*, Tripathi N, Benjamin Jr DB, Hornik CP, Cohen-Wolkowiez M, Clark R, Laughon MM, Smith PB. Analysis of the BPCA Priority List: Are Drug Priorities Reflective of Clinical Need in Hospitalized Infants? Publication 2180.4. PAS 2014.
  12. Batton B, Li L, Newman N, Das A, Watterberg K, Yoder B, Faix R, Laughon M, Stoll B, Higgins R, Walsh M. Early Blood Pressure Patterns, Anti-Hypotensive Therapy & Neurodevelopment in Infants ≤26 Weeks Gestation. Publication #1175.5. PAS 2014.
  13. Malowitz JR*, Hornik CP, Laughon MM, Cotten CM, Clark RH, Smith PB. Management Practice and Mortality in Congenital Diaphragmatic Hernia (CDH). Publication #2926.531. PAS 2013.
  14. Lee JH*, Hornik CP, Testoni D, Laughon MM, Cotten CM, Belcastro MR, Clark R, Smith PB. Hyperglycemia and Risk of Severe Retinopathy of Prematurity (ROP) in Extremely Low Birth Weight Infants. Publication #3180.8. PAS 2013.
  15. Virkud Y*, Hornik CP, Benjamin DK, Laughon MM, Clark RH, Smith PB. Respiratory Support in Very Low Birth Weight (VLBW) Infants Receiving Dexamethasone. Publication #1549.672. PAS 2013.
  16. Patel R, Clark J, Aliaga S, Vyas-Read S, Herring AH, Yoder BA, Clark R, Carlton DP, Smith PB, Laughon MM. Trends in Caffeine Use and Association between Clinical Outcomes and Timing of Therapy in Very Low Birth Weight Infants. Publication #1549.668. PAS 2013.
  17. Swan KN*, Ahlfeld SK, Smith PB, Laughon MM. Review of Randomized Controlled Trials (RCTs) for the Prevention of Bronchopulmonary Dysplasia (BPD). Publication #1547.651. PAS 2013.
  18. Batton BJ, Li L, Newman N, Thomas S, Das A, Watterberg KL, Yoder, BA, Faiz RG, Laughon MM, Stoll B, Higgins RD, Walsh MC. Prospective Observational Study of Blood Pressure Management in Infants 23-26 Weeks Gestation. Publication #1150.2. PAS 2012.
  19. Perez KM*, Chantala K, Herring AH, Smith BP, Clark RH, BejCohen-Wolkowiez M, Laughon M. Sildenafil exposure in the neonatal intensive care unit. Publication # 1533.559. PAS 2012.
  20. Massie SE, Tolleson-Rinehart S, Laughon MM, Powell LM, DeWalt DA, Magnus BE, Thissen D, Price WA. Proxy-reported pulmonary outcomes scale for preterm infants with bronchopulmonary dysplasia. Publication #1533.561. PAS 2012.
  21. Trembath A*, Hornik C, Clark C, Clark R, Smith P, Beitzel M, Laughon M. Comparative effectiveness of three surfactant preparations in premature infants. Publication # 1535.617. PAS 2012.
  22. Aliaga S*, Clark RH, Laughon M, Benjamin DK, Benjamin Jr DK, Smith PB. Decreasing incidence of neonatal invasive candidiasis. Publication #3645.1. PAS 2012.
  23. Batton BJ, Li L, Newman N, Thomas S, Das A, Watterberg KL, Yoder, BA, Faiz RG, Laughon MM, Stoll B, Higgins RD, Walsh MC. Blood pressure values in the first 24 hours for infants 23-26 weeks gestation. Publication #3853.668. PAS 2012.
  24. Aliaga A*, Laughon SK, Long DL, Herring AH, Laughon M, Boggess K, Reddy U, Zhang J. Publication #4524.275. PAS 2012.
  25. Aliaga S*, Boggess K, Ivester T, Price W, Laughon M. Neonatal practice variation influences outcomes for late preterm birth. Publication #4526.373. PAS 2012.
  26. Smith PB, Sherwood A, Cotten CM, Hornik C, Laughon M, Clark R. Mortality of infants less than 30 weeks gestation by day of life. Publication# 4526.405. PAS 2012.
  27. Dasnadi S*, Aliaga S, Laughon M, Marshall DD, Tolleson-Rinehart S, Price W. Comparison of invasive and non-invasive blood pressure measurements in infants. Publication #4528.451. PAS 2012.
  28. Downey CL*, Asher SB, Cotten CM, Hornik CP, Laughon MM, Clark RH, Smith PB. Association of in utero magnesium exposure with spontaneous intestinal perforations in very low birth weight infants. Publication #4530.518. PAS 2012
  29. Condie J*, Sriram S, Schreiber MD, Batton D, Shah B, Bose C, Laughon M, Van Marter L, Allred E, Leviton A, the ELGAN Study Investigators. Early Blood Gas Predictors of Subsequent Respiratory Morbidities in Extremely Low Gestational Age Newborns. Publication #4532.466. PAS 2011. 
  30. S. Aliaga*, P. B. Smith, R. Clark, M. Cohen-Wolkowiez, K. Wade, S. Massie, S. Tolleson-Rinehart, D. K. Benjamin, M. Laughon. Assessment of Off-Label Prescribing Practices of Meropenem in Young Infants. Publication #4521.278. PAS 2011.
  31. Laughon M, Bose C, Allred EN, O’Shea TM, Ehrenkranz RA, Van Marter LJ, Leviton A. Antecedents of chronic lung disease following three patterns of early respiratory disease in preterm infants. Publication #3728.276. PAS 2010.
  32. Bauserman M*, Laughon M, Smith PB, Benjamin DK, Clark R, Engmann C, Cohen-Wolokowiez M. The Epidemiology of Group B Streptococcus and Escherichia coli infections in infants in the era of Intrapartum Antibiotic Prophylaxis.  Publication #2630.2.  PAS 2010.
  33. Aliaga S*, Smith PB, Price W, Ivester T, Tolleson-Rinehart S, McCaffrey M, Laughon M. Regional Variation in Late Preterm Births in North Carolina. Presented at Southeastern Conference on Perinatal Research, Key Largo, Fla., Feb 2010.
  34. Laughon M, Langer J, Wilson D. Walsh M. on behalf of the NICHD Neonatal Research Network. Predictive Models of Bronchopulmonary Dysplasia by Postnatal Day in Preterm Infants. Publication #3450.7. PAS 2009.
  35. Logan JW, O'Shea TM, Allred E, Laughon M, Bose C, Dammann O, Batton D, Leviton A. Early Postnatal Hypotension and Developmental Delay at 24 Months of Age among Extremely Low Gestational Age Newborns. Publication # 4354.425. PAS 2009.
  36. Troy R*, Doron M, Laughon M, Tolleson-Rhinehart, Price W. Reliability of Non-Invasive Blood Pressure Measurements in Extremely Low Birthweight Infants. American Academy of Pediatrics National Conference and Exhibition 2008.
  37. Laughon M, Allred E, O’Shea M, Van Marter LJ, Peden D, Bose C. Pulmonary Deterioration among Extremely Low Gestational Age Newborns (ELGANs): Risk Factors and Relationship to Chronic Lung Disease (CLD). Publication # 7935.9. PAS 2007.
  38. Bose C, Laughon M, Moya F, Aschner J, Donn S, Segal R, Guardia C, Liu G. Late treatment with a peptide-containing, synthetic surfactant for the prevention of bronchopulmonary dysplasia (BPD).  Publication # 6090.4. PAS 2007.
  39. Herrman K*, Bose C, Laughon M.  Spontaneous Closure of the Patent Ductus Arteriosus (PDA) in Very Low Birth Weight Infants with PDAs at Discharge. Publication # 8438.1. PAS 2007.
  40. Cartwright A*, Laughon M, Doron M.  Outcomes of Fetuses and Infants with Lethal Congenital Anomalies: Does Prenatal Diagnosis Make a Difference? Publication # 5145.7. PAS 2007.
  41. South A*, Marshall D, Laughon M.  Growth and Development of Infants with Gastroschisis at 16 to 24 Months. Publication # 5911.45.  PAS 2007.
  42. Laughon M, Bose C, Clark R. Outcomes After Therapies Designed To Prevent or Close the PDA in Preterm Infants. Publication # 5534.196. PAS 2006.
  43. Laughon M, Bose C, Allred E. Van Marter LJ. O’Shea TM. Bednarek F. Leviton A.  Center Variation of Treatment Among Extremely Low Gestational Age Newborns During the First Postnatal Week. Publication # 4856.256. PAS 2006.
  44. Laughon M, Meyer R, Bose C, Wall A, Otero E, Heerens A, Clark R. Rising birth prevalence of gastroschisis. CDC Birth Defects Conference.  Fall 2003.

Teaching activities

 

Mentor or Co-mentor for Faculty

2020-present              Zach Willis, MD

              Assistant Professor of Pediatrics, UNC

 

2020-present              Matthew Loop, PhD

Assistant Professor of Pharmacology, UNC

 

2020-present              Morika Williams, PhD

              Assistant Professor of Medicine, UNC

 

2020-present              Dana McCarty, DPT

              Assistant Professor of Health Sciences, UNC

 

2019-present                Genevieve Taylor, MP, MPH

                               Assistant Professor of Pediatrics, UNC

 

2018-present                 Wesley Jackson, MD, MPH

                               Assistant Professor of Pediatrics, UNC

 

2018-present              Nicolas Bamat, MD, MPH

              Assistant Professor of Pediatrics, CHOP

 

2015-present              Rachel Greenberg, MD

              Associate Professor of Pediatrics, Duke

 

2014-present              Daniel Gonzalez, PharmD, PhD

              Associate Professor of Pharmacology, with Tenure, UNC

 

2012-present              Melissa Bauserman, MD, MPH

              Associate Professor of Pediatrics, UNC

 

2010-present              Sofia Aliaga, MD, MPH

              Associate Professor of Pediatrics, UNC

 

2015-2018              Lawrence Ku, MD

              Assistant Professor of Pediatrics, Duke

              Current role: Assistant Professor, Mercy Health NICU, Michigan

 

2013-2015              Kevin Watt, MD

              Associate Professor of Pediatrics, Duke

              Current role: Professor of Pediatrics, Utah

 

2013-2015              Kevin Hill, MD

              Associate Professor of Pediatrics, Duke

 

Mentor or Co-mentor for Subspecialty Residents, Doctoral Candidates, or Post-docs

2020-present              Lana Zhang, MD

  • Dexamethasone pharmacokinetics

 

2019-2022              Christopher Zimmerman, MD

  • Anti-hypertensive pharmacokinetics
  • Current position: Adjunct UNC Faculy, Women’s Hospital Greensboro

 

2018-2021                Dennis Leung, MD; PICU fellow

  • Gabapentin in the NICU and PICU
  • Current position: Neuro critical care fellow, Johns Hopkins

 

2016-2019              Genevieve Taylor, MD; NICU fellow

  • Surfactant in late preterm infants
  • Current position: Assistant Professor, UNC

 

2015-2018              Wesley Jackson, MD; NICU fellow

  • Sildenafil in premature infants
  • Severe BPD in premature infants
  • Current Position: Assistant Professor, UNC

 

2014-2016              Jessica Ericson, MD (Duke); Peds ID fellow

  • Chorioamnionitis
  • Current position: Assistant Professor, Hershey Medical Center

 

2013-2015              Susan Hupp, MD (Duke); PICU fellow

  • Risk factors for retinopathy of prematurity
  • Current Position: Assistant Professor, UT Southwestern

 

2012-2015              Nicole Zane, PharmD, PhD

  • PBPK of sildenafil in premature infants
  • Current Position: Research Scientist, CHOP

 

2012-2015              Yamini Verkud, MD (Duke); AIR fellow

  • Dexamethasone and risk of BPD

 

2012-2013              Daniel Gonzalez, PharmD, PhD

  • PK of sildenafil in premature infants
  • Current Position: Assistant Professor, UNC School of Pharmacy

 

2010-2012              Kevin Watt, MD (Duke); PICU fellow

  • Moxifloxacin in premature infants
  • Current Position: Assistant Professor, Duke

 

2009-2012              Andrea Trembath, MD; NICU fellow

  • Examining the use of surfactant in the Pediatrix database
  • Current position: Associate Professor, UNC

 

2009-2012                   Melissa Bauserman, MD; NICU fellow

  • Examining the epidemiology of E. coli and GBS serious bacterial infections in the Pediatrix database
  • Current position: Associate Professor, UNC

 

2008-2011                   Lynn Johnson, MD

  • Correlating magnesium concentration in cord blood with the level of resuscitation in infants enrolled in the Maternal Fetal Medicine Unit Beneficial Effect of Antenatal Magnesium (BEAM) RCT
  • Current Position: Attending Neonatologist, Richmond, VA

 

2008-2011              Gina Abelli Geis, MD

  • Effect of a neonatal hospice program
  • Current position, Associate Professor, SUNY Albany

 

2007-2010              Sofia Aliaga, MD, MPH

  • Late preterm birth (34-36 weeks) in NC
  • Current position: Associate Professor, UNC

 

2006-2009                   Rachel Troy, MD             

  • Invasive vs. non-invasive blood pressure monitoring in preterm infants
  • Current position: Attending Neonatologist at INOVA Fairfax, Fairfax, VA

 

2005-2008              Andrew South, MD, MPH

  • Neurodevelopmental and gastrointestinal outcomes at 12-24 months of infants with gastroschisis
  • Current position: Associate Professor at Akron Children’s

 

2005-2008              Kristy Herrman, MD

  • Natural history of a patent ductus arteriosus diagnosed at discharge in preterm infants
  • Current position: Attending Neonatologist at Dell Children’s Hospital, Austin, TX

 

Research Mentor for Residents

2010              Krystle Perez, MD

  • Sildenafil use in the Pediatrix Data Warehouse

 

2008              Kristi Lewis, MD

  • Natural history of a patent ductus arteriosus diagnosed at discharge in preterm infants

 

2004              Warren Eng, MD

  • Examined sweat testing in term and preterm infants

 

Research Mentor for Graduate Students

2010              Laurie Stockton, MPH (Epidemiology, UNC Gillings School of Public Health)

  • Cochrane review on intravenous indomethacin for symptomatic PDA in preterm infants

 

Research Mentor for Medical Students

2021                               Zach Stern

  • Positive health outcomes in premature infants

 

2021                               Haejung Yoon

  • Epidemiology of congenital cytomegalovirus and pharmacoepidemiology of ganciclovir and valganciclovir

 

2014                               Blair Hanvey

  • Informed consent

 

2012              Kristyn Swan

  • Doris Duke Fellowship (Laughon, Mentor)
  • Randomized trials of therapeutics for bronchopulmonary dysplasia review
  • Concordance between CSF and blood cultures in hospitalized infants

 

2009              Kelly Salter

  • Performed a Cochrane review on prophylactic nasal intermittent positive pressure ventilation vs. nasal continuous positive airway pressure in preterm infants
  • Grant listed to UNC School of Medicine website as exemplary proposal

 

2006              Ashley Fairbrother

  • Correlated weight loss with serum sodium at 24 hours postnatal age in infants < 1500 grams birth weight
  • Presented at UNC Medical Student Research Day in January of 2007

 

Research Mentor for High School Students

2013              Kimlynn Ngo

              NC School for Science and Math

  • Factors affecting informed consent in premature infant trials

 

 

 

Laughon Clinical Research Conference

I conduct a clinical research conference every other week on Wednesdays from 1-2 PM. In these conferences, trainees present works in progress, we review data/tables/figures for abstracts and manuscripts, and review other topics such as NIH funding mechanisms. We also review aims pages for grant submissions. This is attended by neonatal-perinatal fellows, PICU fellows, Maternal-fetal medicine (OB/GYN) fellows, and UNC medical students, PhDs from the UNC school of pharmacy, and neonatologists at Harvard and CHOP.

 

Lectures for Subspecialty Residents

Neonatal-Perinatal

2021                                          Respiratory Distress Syndrome

2020                                          Meconium Aspiration Syndrome

2015, 13, 11, 08, 05              Apnea of Prematurity

2009, 2005                            Liver Disease of the Newborn

2006                                          Management of Patent Ductus Arteriosus I

2006                                          Management of Patent Ductus Arteriosus II

2006                                          Surfaxin: a new synthetic surfactant              

             

Pediatric Pulmonary

2008                                          Treatments for Bronchopulmonary Dysplasia

 

All Subspecialty Residents

2007                                               How to Prepare for a Journal Club

2005                                             How to Read the Literature

 

Lectures for Pediatric and Medicine/Pediatric Residents: Monthly curriculum

2015, 13, 05                            Fluid therapy

2012                                          Blood Gases

2011                                          Hypoxic-ischemic encephalopathy

2010, 05                            Diagnostic Tests

2009                                          Respiratory Distress syndrome

2008                                          Pulmonary Hypertension of the Newborn

2007                                          How to Read a Paper

2007                                          Respiratory Distress Syndrome

2007                                          Basic Statistics

2007                                          Neonatal Nutrition

             

Lectures for Medical Students

2016, 14, 08, 06              Pediatric Interest Group

2008, 09, 10                            Congenital Diaphragmatic Hernia

2007                                          Respiratory Distress Syndrome

2007                                          Pediatric Interest Group

2006                                          Respiratory Distress Syndrome

2005                                          Acute Care Pediatrics: Neonatal Ventilation             

 

Other Lectures

2006                                          Surfaxin: a new synthetic surfactant

                                          Carolina Air Care (Transport Education Meeting)

2005                                          Surfaxin: a new synthetic surfactant

                                          UNC Center for Maternal and Infant Health

2005                                          Development of Chronic Lung Disease of Prematurity

                                          UNC K30/Clinical Research Curriculum

 

Visiting Professor

03/2021              University of New Mexico, Albuquerque, NM

02/2021              The University of Alabama at Birmingham, Birmingham, AL

02/2021              Women and Infants (Brown), Providence, RI

01/2021              SUNY Rochester, Rochester, NY

10/2020              Stanford University, Palo Alto, CA

09/2020              Case Western Reserve University, Cleveland, OH

03/2019              Cincinnati Childrens, Cincinnati, OH

05/2018              UTSW Children’s Hospital (Parkland), Dallas, TX

03/2018              Nationwide Children’s Hospital, Columbus, OH

02/2018              Tufts University Floating Hospital for Children, Boston, MA

06/2017              New Hanover Neonatology Associates, Wilimington, NC

10/2014              University of Louisville, Kosair Children’s Hospital, Louisville, KY

09/2014              University of Florida-Jacksonville, Jacksonville, FL

12/2013              Columbia University, New York, NY

10/2013              Karolinska Institute, Stockholm, Sweden

05/2013              University of Ottawa, Ottawa, CA

10/2012              Emory University, Atlanta, GA

03/2012              Children’s Mercy, Kansas City, MO

01/2012              The University of Alabama at Birmingham, Birmingham, AL

 

Invited Presentations

Title

Conference

Location

Date

PDA Management

Argentinian Neonatal Conference

Buenos Aires, Argentina

11/2021

Pediatric Trial Network

AAP NCE

Orlando, FL

11/2018

Therapeutic Update

AAP NCE

Orlando, FL

11/2018

Furosemide in premature infants

Hot Topics

Washington, DC

12/2017

Late onset sepsis

Arab Neonatology Conference

Dubai, UAE

05/2017

Early onset sepsis

Arab Neonatology Conference

Dubai, UAE

05/2017

Late onset sepsis

NeoPREP

Atlanta, GA

01/2016

Early onset sepsis

NeoPREP

Atlanta, GA

01/2016

BPD Prevention

Hot Topics in Neonatology

Washington, DC

12/2015

Development of the BPD estimator

University of Miami NEO conference

Miami, FL

11/2014

Evidence based use of medications in ELBW infants

University of Miami NEO conference

Miami, FL

11/2014

Innovative clinical trial design in neonatology

Neonatal Pharmacology

Boston, MA

05/2014

Medication controversies in ELBW Infants

The NEO Conference

Orlando, FL

02/2014

Controversies in the Treatment of Patent Ductus Arteriosus

PDA Consensus Conference

Austin, TX

05/2013

Controversies in the Treatment of Patent Ductus Arteriosus

EBNEO

Istanbul, Turkey

03/2013

Bronchopulmonary dysplasia prediction

Hot Topics in Neonatology

Washington, DC

12/2012

Pediatric Trials Network

Hot Topics in Neonatology

Washington, DC

12/2012

Controversies in the Treatment of Patent Ductus Arteriosus in Preterm Infants

Heart conditions of the neonate

San Antonio, TX

09/2011

Dissemination of a new meropenem dose in infants

Best Pharmaceuticals for Children’s Act conference

Washington, DC

11/2010

Conservative approach to the Patent Ductus Arteriosus in Preterm Infants

PDA symposium

Stuttgart, Germany

09/2010

Late surfactant therapy in preterm infants

Dialogues in Neonatal-Perinatal Medicine

Durham, NC

04/2010

Patent ductus arteriosus

The NEO conference

Orlando, FL

02/2009

Blood pressure in preterm infants

5th Annual Prematurity Conference

Chicago, IL

11/2008

Controversies in the Treatment of Patent Ductus Arteriosus in Preterm Infants

National Association of Neonatal Nurses

Washington, DC

06/2008

Controversies in the Treatment of Patent Ductus Arteriosus in Preterm Infants

Grand Rounds, Dell Children’s Hospital

Austin, TX

04/2008

What is Hypotension in the Newborn and How do We Treat It?

Newborn Day

Hickory, NC

04/2008

What is “normal blood pressure” in the preterm infant?

Hot Topics in Neonatology

Washington, DC

12/2007

Patent ductus arteriosus

Newborn Day

Charleston, WV

04/2006

Diagnostic Testing

Grand Rounds, New Hanover Regional Medical Center

Wilmington, NC

08/2005

Patent ductus arteriosus

North Carolina Neonatologist Association

Durham, NC

04/2005

 

UNC Neonatal-Perinatal Research Symposium

June 2021: I organized an international symposium to identify best practices for patent ductus arteriosus trials. This was CME conference and there were 100 attendees. Faculty included Ronald Clyman (UCSF), Willem-Pieter de Boode (Australia), Koert De Waal (Belgium), Tarah Colaizy (Iowa), Aisling Smith (Ireland), Samir Gupta (England).

https://www.med.unc.edu/pediatrics/npm/research/laughon-research/research_symposium/

 

Clinical Service

Daily Rounds

Each year, I spent a total of 6-12 weeks on service attending in the Newborn Critical Care Center.  I teach on formal rounds approximately 2.5 to 3 hours/day.

 

Night Rounds

Each night that I am on call (in house) in the hospital (approximately once per month), I teach nurse practitioners and residents on formal rounds for approximately 1.5 hours per night. In addition, I teach nurse practitioners and residents about admissions (approximately 1 hour per admission; average number of admissions per night=2) and when there is a sick patient (up to 8-10 hours of direct bedside supervision of procedures and teaching about acute physiology).

 

Direct Supervision of the Critically Ill Neonate

I directly supervise and teach subspecialty residents, residents, and nurse practitioners about the critically ill neonate including: stabilizing and management of extremely low gestational age newborns (22-27 weeks gestational age), pre- and post-operative care of infants receiving surgery (e.g., gastrostomy tube, tracheostomy tube, intestinal procedures), and infants requiring advance ventilation techniques (e.g. high frequency oscillatory ventilation, high frequency jet ventilation).

 

Direct Supervision of Procedures

I directly supervise and teach the following procedures for fellows, residents, and interns: intubation, thoracostomy tube placement, central line placement (i.e. umbilical arterial catheter and umbilical venous catheters), thoracentesis, pericardiocentesis, pleurocentesis, etc.

 

Direct Supervision of Delivery Room Care

I directly supervise and teach subspecialty residents (fellows), residents, and interns of delivery room care and resuscitation ranging from routine newborn care to intubation, chest compressions, emergency central line placement, and the administration of cardiac stimulating medications such as epinephrine.

 

Supervision of the Pediatric Transport Team

I directly supervise the UNC Air Care Pediatric Transport Team when I am the Medical Control Officer.  The UNC Air Care team consists of a nurse and a respiratory therapist.

 

Fellow Activities

I review and critique condolence letters written by fellows to NCCC families whose infants died in our NICU. I review and critique the death summaries written by NPM Fellows for Morbidity and Mortality conference. 

 

 

Grants and Contracts

 

Active:

R61HL147833                                                                                                   8/19-7/24

NHLBI                                                                                                                               $7,500,000

Sildenafil in Premature Infants with Severe Bronchopulmonary Dysplasia: This is a 120 participant, 30 site trial to assess the safety, preliminary effectiveness, and PK of sildenafil in premature infants with severe bronchopulmonary dysplasia.

MPI: Laughon (other MPI Hornik, Duke)

15% effort

 

Mentorship of Early-Career Clinicians in BPD Drug Therapies              8/19-7/24

NHLBI K24HL143283                                                                                                  $612,520

Provides salary support for mentoring clinicians to develop clinical pharmacology expertise in drug therapies for bronchopulmonary dysplasia.

PI: Laughon

25% effort

 

Sildenafil safety in premature infants                                                                      9/18-9/22

FDA R01FD006099                                                                                                  $1,200,000

Sildenafil PK and preliminary effectiveness in premature infants at risk of BPD: This is a 25 center, 120 participant dose-ranging trial of sildenafil to prevent bronchopulmonary dysplasia. This is co-funded with PTN.

PI: Laughon

25% effort

 

Safety of sildenafil in premature infants at risk of BPD                            9/15-9/22

NICHD: HHSN275201000003I                                                                      $3,000,000

This is a 25 center, 120 participant dose-ranging safety trial of sildenafil in premature infants at risk of bronchopulmonary dysplasia.

PI: Benjamin

Role: Protocol Chair

5% Effort

 

NICHD Pediatric Trials Network                                           6/18-5/25