William E Truog, MD
Disclosures: Nothing to disclose
OMB No. 0925-0046, Biographical Sketch Format Page

 

OMB No. 0925-0001 and 0925-0002 (Rev. 09/17 Approved Through 03/31/2020)

BIOGRAPHICAL SKETCH

Provide the following information for the Senior/key personnel and other significant contributors.
Follow this format for each person.  DO NOT EXCEED FIVE PAGES.

NAME: Truog, William E.

eRA COMMONS USER NAME (credential, e.g., agency login): wetruog

POSITION TITLE: Sosland Family Endowed Chair in Neonatal Research, Professor of Pediatrics, University of Missouri-Kansas City School of Medicine

EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)

INSTITUTION AND LOCATION

DEGREE

(if applicable)

 

Completion Date

MM/YYYY

 

FIELD OF STUDY

 

 

 

 

 

Carleton College, Northfield, Minnesota

BA (cum laude)

1969

Biology

University of Chicago-Pritzker School of Medicine, Chicago, IL

MD

1973

Medicine

University of Washington/Children’s Hospital and Medical Center, Seattle, Washington

Residency/Chief Residency /Fellowship

1973-1978

Pediatrics and Neonatal-Perinatal Medicine

 

 

A.              Personal Statement

My professional goal is to identify and test potentially efficacious and safe therapies and practices for term and preterm infants at high-risk for death or disability, particularly from pulmonary disorders. I have experience and some expertise in conception, design, performance, interpretation, and publication of clinical and translational research in neonatal medicine.

 

B.              Positions and Honors

Faculty Positions

1978-1993              Assistant Professor (1978-1982), Associate Professor (1982-1987), Professor (1987-1993), Department of Pediatrics, Division of Neonatal and Respiratory Diseases, University of Washington, Seattle

1993-              Professor of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri

2003-2011                            Adjunct Professor, Molecular and Integrative Physiology, University of Kansas School of Medicine, Kansas City, Kansas

2009-2016                            Associate Chair, Department of Pediatrics, University of Missouri-Kansas City School of Medicine             

2008-                            Director, Center for Infant Pulmonary Disorders, Children’s Mercy-Kansas City, Kansas City, Missouri

2009-2018                            Director, Office of Faculty Development, Children’s Mercy-Kansas City, Kansas City, Missouri

 

Other Experience and Professional Memberships

1993-2007              Neonatal-Perinatal Medicine Fellowship Program Director, Children's Mercy Hospitals and Clinics, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri

2000-2003              Chairman of Organization of Neonatal-Perinatal Training Program Directors Council

2008,2010              Member, Special Emphasis Review Panels, NHLBI and NICHD

2010-2013              Editorial Board, NeoReviews

2014-2017              Section of Neonatal Pediatrics, AAP representative to Planning Committee for annual PAS Meeting

2012-              BPD Collaborative, Site PI and Steering Committee Member

 

Honors

 

1993-2008              First “Children’s Mercy Hospital Physician Scientist” Award, Children's Mercy-Kansas City,                         Kansas City, Missouri

1999-              Recipient, Kraemer Pediatric Research Excellence Award, Children’s             

                            Mercy Hospital

2001-                Named as Sosland Family Endowed Chair in Neonatal Research

                Children’s Mercy Hospitals, Kansas City, Missouri

2003-              Named to Who’s Who in America, Marquis Publications Board

2005-                Selected to Best Doctors in America 2005-2015

2006-                Named to Who's Who in American Education

2008                Founder’s Award, Midwest Society for Pediatric Research

2008-              American Men and Women of Science

2011-2016              Kansas City Super Doctors

 

C.              Contributions to Science
 

  1. Miscellaneous clinical trials/reviews

.

    1. Rosterman JL, Pallotto EK, Truog WE, Escobar H, Meinert KA, et al. The impact of neurally adjusted ventilatory assist mode on respiratory severity score and energy expenditure in infants:  a randomized crossover trial. J Perinatol. 2018;38:59-63.
    2. Abman SH, Collaco JM, Shepherd EG, Keszler M, Cuevas-Guaman M, Welty SE, Truog WE, et al. Interdisciplinary care of children with severe bronchopulmonary dysplasia. J Pediatr. 2017;181:12-28.
    3. Watterberg KL, Fernandez E, Walsh MC, Truog WE, Stoll BJ, et al. Barriers to enrollment in a randomized controlled trial of hydrocortisone for cardiovascular insufficiency in term and later preterm newborn infants. J Perinatol. 2017;37:1220-1223.
    4. Cuna A, Govindarajan S, Oschman A, Dai H, Brophy K, Norberg M, Truog WE. A comparison of 7-day versus 10-day course of low dose dexamethasone for chronically ventilated preterm infants. J Perinatol. 2017;37:301-305.

 

  1. Trial of late surfactant
    1. Keller RL, Eichenwald EC, Hibbs AM, Rogers EE, Wai KC, Black DM, Ballard PL, Asselin JM, Truog WE, et al. The randomized controlled trial of late surfactant: effects on respiratory outcomes at 1-year corrected age. J Pediatr. 2017;183:19-25.
    2. Wai KC, Kohn MA, Ballard RA, Truog WE, Black DM, et al. Early cumulative supplemental oxygen predicts bronchopulmonary dysplasia in high risk extremely low gestational age newborns. J Pediatr. 2016;177:102.
    3. Ballard RA, Keller RL, Black DM, Ballard PL, Merill JD, Eichenwald EC, Truog WE, et al.

Randomized trial of late surfactant treatment (TOLSURF) in ventilated preterm infants receiving

inhaled nitric oxide. J Pediatr. 2016;168:23-29.

    1. Lewis T, Truog W, Norberg M, Ballard Pl, et al. Genetic variation in CRHR1 is associated with short-term respiratory response to corticosteroids in preterm infants at risk for bronchopulmonary dysplasia. Pediatr Res. 2018 (epub ahead of print)

 

  1. Use of databases to better understand pulmonary outcomes
    1. Cuna A, Liu C, Govindarajan S, Queen M, Dai H, Truog WE. Usefulness of an online risk estimator for bronchopulmonary dysplasia in predicting corticosteroid treatment in infants born preterm. J Pediatr. 2018;197:23-28..
    2. Cuna A, Lewis T, Oschman A, Dai HY, Brophy K, Norberg M, Nyp M, Truog WE. outcomes of infants who failed to extubate despite systemic corticosteroids. Am J Perinatol. 2017;34:1558-1463.
    3. Murthy K, Porta NFM, Lagatta JM, Zaniletti I, Truog WE, et al. Inter center variation in death or tracheostomy placement in infants with severe bronchopulmonary dysplasia. J Perinatol. 2017;37:723-727.
    4. Truog WE, Nyp MF, Taylor J, Gratny LL, Escobar H, et al. Infants born at <29 weeks: pulmonary

outcomes from a hybrid perinatal system. J Perinatol. 2014: 34:59-63.

    1. Nyp MF, Taylor JB, Norberg M, Truog WE. Impaired growth at birth and bronchopulmonary

dysplasia classification: beyond small for gestational age. Am J Perinatol. 2015;32:75-82.

 

  1. Contributions of the NRN (named author)
    1. Walsh MC, Bell EF, Kandefer S, Saha S, Carlo WA, D’Angio CT, Laptook AR, Sanchez PJ, Stoll BJ, Shankaran S, Van Meurs KP, Cook N, Higgins RD, Das A, Newman NS, Schibler K, Schmidt B, Cotten CM, Poindexter BB, Wattergerg KL, Truog WE. Neonatal outcomes of moderately preterm infants compared to extremely preterm infants. Pediatr Res. 2017;82:297-304.
    2. Shankaran S, Laptook AR, Pappas A, McDonald SA, Das A, et al. Effect of depth and duration of cooling on deaths in the NICU among neonates with hypoxic ischemic encephalopathy: a

randomized clinical trial. JAMA. 2014;312:2629-2639.

    1. Truog WE, Nelin LD, Das A, Kendrick DE, Bell EF, et al. Inhaled nitric oxide usage in preterm

infants in the NICHD Neonatal Research Network: inter-site variation and propensity evaluation. J Perinatol. 2014:34-842-846.

    1. Stoll BJ, Hansen NI, Bell EF, Walsh MC, Shankaran S, Laptook AR, Sanchez PJ, Van Meurs KP, Wyckoff M, Das Abhik, Hale EC, Ball MB, Newman NS, Schibler K, Poindexter B, Kennedy K, Cotton CM, Watterberg KL, D’Angio CT, DeMauro SB, Truog WE, Devaskar U, Higgins RD; for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Trends in care practices, morbidity, and mortality of extremely preterm neonates, 1993-2012. JAMA.2015;314:1039-1051.
    2. Truog WE, Guest editor “The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Neonatal Research Network (NRN): Highlights of Neonatal Research. Semin Perinatol.2016: Issue 40; entire issue.
    3. Phelps DL, Watterberg KL, Nolen TL, Cole CA, Cotten CM, Oh W, Poindexter BB, Zaterka-Baxter KM, Das A, Lacy CB, Scorsone AM, Walsh MC, Bell EF, Kennedy KA, Schibler K, Sokol GM, Laughon MM, Lakshminrusimha S, Truog WE, Garg M, Carlo WA, Laptook AR, Van Meurs KP, Carlton DP, Graf A, DeMauro SB, Brion LP, Shankaran S, Orge FH, Olson RJ, Mintz-Hittner H, Yang MB, Haider KM, Wallace DK, Chung M, Hug D, Tsui I, Cogen MS, Donahue JP, Gaynon M, Hutchinson AK, Bremer DL, Quinn G, He YG, Lucas WR Jr, Winter TW, Kicklighter SD, Kumar K, Chess PR, Colaizy TT, Hibbs AM, Ambalavanan N, Harmon HM, McGowan EC, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Effects of Myo-inositol on Type 1 Retinopathy of Prematurity Among Preterm Infants <28 Weeks' Gestational Age: A Randomized Clinical Trial. JAMA 2018;320;1649-1658.

 

D.              Additional Information: Research Support and/or Scholastic Performance (total of ~170 peer reviewed publications)

 

Ongoing Research Support

 

NICHD NRN U-10 HD068284 Children’s Mercy Hospital/Truman Medical                                                         04/11 03/21

Centers and the University of Missouri-Kansas City School of Medicine: A

New Addition for the Next Five Years (2011-2016)

PI: WE Truog

 

Administrative continuation                                                                                                                                                                                      04/16 – 03/21

 

Local

 

  1. Sosland Endowed Chair Endowment and Cooper Connor Endowed Fund                            

in support of the Children’s Mercy Center for Infant Pulmonary Disorders